Failures of heavy-duty vehicles during load hauling are major concern in road transportation. This is due to the magnitudes of accidents that sometimes result from the failures with loss of lives, destruction of goods or spillage with treat to environment, and road blockages. The failures are particularly detestable to the vehicle owners owing to the much loss they can incur including litigations they can face and compensations they can be obliged to make to affected innocent victims. In this paper, shell failure analysis of a semi-trailer tanker owned by an oil marketing company which resulted in much loss of its full-tank carried oil has been investigated. The information provided can be useful for forestalling recurrent failure problems with the company’s fleet of semi-trailers which had caused the company substantial losses in its annals. The shell was first examined visually to assess the nature and magnitude of the failure and where it occurred. Maintenance records of the vehicle was surveyed and collected samples from critical locations of the shell was analyzed with respect to chemical composition, metallographic structure, and corrosion behaviors. Visual inspections indicated that the shell failed by small brittle crack perforation along the seam of a previous weld repair. Surveys showed no clear standard maintenance records of the semi-trailer. Chemical analysis showed steel material of different composition at the failure location compared to the as-made shell carbon steel. Metallographic analyses showed that the failure location was heterogeneous compared to the as-made shell steel. Corrosion analyses showed greater corrosion rates at the failure location which presumably raised the location stresses amid dynamic effects from bad road conditions and caused the shell to crack-perforate along the weld seam of the location.