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Topics: Adherence, Medication, Treatment, Outcome, Myocardial infarction
Introduction : Quality of life is a set of situations that contribute to people's well-being. In pregnant women, it is necessary to explore the emotional, social and physical aspects. Few studies in the Latin American population explore the quality of life of pregnant women. The objective was to establish the frequency of deterioration of the physical, psychological, social and environmental quality of life and to identify the associated factors in pregnant women residing in cities of the...
Topics: Quality of life, Pregnancy, Women health, Mental health, Prenatal care, Obstetrics, Maternal health
Pierre Robin sequence (PRS) is an inherited disorder that affects one in between 8,500 and 14,000 people and is characterized by a triad of clinical signs. These include micrognathia, glossoptosis and obstruction of the upper airway, typically associated with palatal cleft. PRS has also been associated with various ocular complications, including high congenital myopia, congenital glaucoma, and retinal detachment. Because of the clinical importance of PRS, it is critical to illustrate the...
Topics: Keratoconus, Pierre Robin syndrome, Cornea, Corneal topography
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Topics: Pigmented lesions, Melanonychia, Dermoscopy, Nevus, Melanoma, Pediatric
Introduction : Liver cancer is one of the most common malignant tumors in the world, and patients with liver cancer are often in the middle and late stages of cancer when they are diagnosed. Copper death is a newly discovered new cell death method. It is a copper-dependent and regulated cell death method. At the same time, Long noncoding RNAs (LncRNAs) also play an important regulatory role in the pathological process of tumors such as liver cancer. Materials and methods : First, the expression...
Topics: CuProtosis, Immunotherapy, Bioinformatics, LncRNA, Hepatocellular carcinoma
Introduction : Low levels of vitamin D have been linked to raised periodontal inflammation, a higher concentration of periodontopathogens, greater periodontal destruction, and more severe periodontitis. This study aimed to assess the influence of vitamin D and calcium levels on periodontitis. Material and methods : A search for studies on vitamin D, calcium, and periodontal disease was conducted in the following databases: PubMed (MEDLINE, Cochrane Library), Web of Science (WoS), and Scopus....
Topics: Calcium, Periodontitis, Risk, Vitamin D
Introduction : Chronic low back pain (cLBP) is associated with a dynamic interaction of multiple psychological factors that act as predictors of recovery time. Our goal was to quantify the association between pain intensity and psychological variables. Material and methods : A cross-sectional study using convenience sampling was conducted at Universidad Europea de Canarias (Spain) between January 24, 2022 and June 10, 2022. In addition, adults and children with cLBP older than 13 years with...
Topics: Chronic low back pain, Psychological factors, Quality of life
Introduction : Postoperative blood loss after prostate surgery is thought to be associated with an increase in urinary fibrinolytic activity. We investigated the effects of the local dilution of fibrinolytic agents with manual irrigation on postoperative bleeding after the transurethral resection of the prostate (TUR-P). Materials and methods : Between April 2017 and April 2021, 128 patients were prospectively randomised into two equal groups. Monopolar TUR-P was applied to all patients for...
Topics: Transurethral prostatectomy, Postoperative bleeding, Irrigation
Introduction : Glaucoma is a leading cause of irreversible blindness worldwide; several risk factors have been identified as major underlying causes for developing this condition. Optic disc hemorrhage has been identified as a risk factor for the development and progression of primary open-angle glaucoma, as well it has been related to playing an important role in normal-tension glaucoma. Material and methods : A cross-sectional study was conducted in Colombia among hypertensive and diabetic...
Topics: Open angle glaucoma, Optic disc hemorrhage, Systemic hypertension, Diabetes mellitus, Intraocular...
According to the global report on birth defects in 2021, it is estimated that 8 million children are born with birth defects of genetic origin annually. These birth defects vary in their degree of severity; where some types are mild and do not require treatment but others may necessitate lifelong medications or even cause instant death just after birth. That is why prenatal screening is doubtless necessary to detect such genetic defects before birth aiming to drop the tragedy of these children...
Topics: Non-invasive prenatal tests, Cell free fetal DNA, Chromosomal microarray, Chorionic villus...
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Topics: Myasthenia gravis, Thymoma, Ptosis
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Topics: Carcinoma stomach, Hemorrhoids, Cholelithiasis
Introduction : Spinal cord injury results in disability, limited participation in physical activities, and mental health problems which greatly affects the quality of life of the injured person. Engaging in physical activity is necessary for optimal recovery in individuals with spinal cord injury. Chronic spinal cord injury patients suffer from many secondary complications which become a challenge for the patient and the health care community to manage due to which recovery will be complex and...
Topics: Physical activity, Spinal cord injury, Depression
Introduction : Healthcare professionals (HCPs) play a key role in the prevention of catheter-associated urinary tract infections (CAUTI). This study aims to determine the compliance of healthcare personnel with urethral catheterisation standards and the factors affecting it. Materials and Methods : This study is a prospective survey and was conducted between February and March 2021 after ethical approval and patient consent. An internet-based, structured 39-item questionnaire was sent via email...
Topics: Urinary tract infection, Catheter, Health personnel, Knowledge, Prevention
The development of electrocardiography, one of the top scientific breakthroughs of the 20th century, occurred in the field of cardiology. The history of the ECG began long before its invention, with the advent of the study of electricity in the medical field. The idea of electrophysiology and Waller's initial recording of the ‘electrogram’ encouraged Willem Einthoven to develop new string galvanometers and turn this remarkable physiologic occurrence into a vital clinical recording tool. It...
Topics: Electrocardiography, Electrocardiogram, Electrophysiology, Cardiology, History
Introduction : Geriatric syndromes are associated with morbidity and poor quality of life (QOL). Urinary incontinence (UI) is one of the most prevalent geriatric syndromes. However, there is little research on the association of UI and UI-related QOL with other geriatric syndromes. The aim of this exploratory study were to examine the effect and coexistence of geriatric syndromes, admission type and surgical severity on UI-related QoL in patients hospitalized in the urology clinic. Materials...
Topics: Urinary incontinence, Geriatric syndrome, Quality of life, Urology
Introduction : Trastuzumab emtansine (T-DM1) is one of the effective treatment options in human epidermal growth factor receptor 2 (HER2) positive breast cancer patients. In this study, we aimed to find the effect of T-DM1 on survival, its tolerability and prognostic factors of T-DM1 treatment. Material and methods : The study was designed as a single-center, retrospective study that included patients treated in the oncology department of a university hospital in Turkey. HER2-positive patients...
Topics: Metastatic breast cancer, Trastuzumab emtansine, Survival, Adverse events
The introduction of the drug-eluting (DES) stent to percutaneous coronary intervention (PCI) had a significant impact on patient management of coronary artery disease and has been called the “third revolution” in interventional cardiology after the first 2 revolutions of balloon angioplasty and bare-metal stents. The promise of adaptive remodeling, restoration of vasomotion, late luminal enlargement, and retained potential for future coronary artery bypass grafting at the site of previous...
Topics: Bioresorbable scaffolds, Angioplasty, Coronary stents
Breast is an uncommon site of extra nodal lymphoma accounting for 2.2% of all extra nodal lymphomas. B cell lymphomas are more common than T cell types. The most common subtype is Diffuse Large B Cell Lymphoma. Breast lymphoma is very challenging to diagnose as it has nonspecific clinical and radiological features. We report a rare case of primary T cell lymphoma in a 20-year-old female. It was misdiagnosed as abscess on ultrasound and as suppurative mastitis on fine needle aspiration cytology...
Topics: ALCL, Breast, Extranodal, Non-Hodgkin lymphoma, T cell lymphoma
Introduction : Coronary artery ectasia (CAE) is one of the uncommon cardiovascular disorders with a clinical spectrum ranging from asymptomatic cases to myocardial infarction. Atherosclerosis plays a pivotal role in the pathogenesis of CAE. Recently, it has been determined that the atherogenic index of plasma (AIP) is a strong predictive marker for atherosclerosis. The aim of this study was to investigate whether there is a relationship between obstructive CAE and AIP in patients with non-ST...
Topics: Atherogenic index of plasma, Angiography, Coronary artery ectasia, Myocardial infarction
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Topics: Alzheimer, Cognition, Delirium
Introduction : Despite the increased survival rates follow up studies of preterm born children have documented increased prevalence of neurodevelopmental disabilities and cognitive deficits. By using psychiatric assessment, we aimed to evaluate cognitive functions by comparing preterm born babies according to the week of gestation by comparing the scores of the Wechsler Intelligence Scale for Children-Revised Form (WISC-R) in childhood. Material and methods : Children with a history of birth as...
Topics: Preterm, Cognitive functions, WISC-R Scores
Cardiac implantable electronic device (CIED) infections have been rising around the world. Many microorganisms can lead to this disease. Corynebacterium species are catalase-positive Gram-positive bacilli, also known as "diphtheroids" or "coryneform" bacteria, were once almost universally dismissed as contamination when recovered from patients, but they are now increasingly being linked to serious infections and have the ability to form biofilms and rarely cause CIED...
Topics: Corynebacterium, Endocarditis, Cardiac implantable electronic device
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Topics: Hemangioma, Infant, Child, Adolescent, Adrenergic Beta-antagonists
Introduction : Low back pain appears in approximately two thirds of the population at some point in life and when it exceeds more than 12 weeks, it evolves to chronic low back pain. Chronic low back pain is considered one of the most common causes of disability and absence from work. A therapeutic technique that can be used as a treatment for chronic low back pain is neural mobilization, capable of restoring compromised neurological structures, restoring movement by improving the elasticity of...
Topics: Backache, Nervous tissue, Physiotherapy, Manual therapy
Introduction : Plasmids carry and transport genes that assist their hosts to survive in many environments. Many studies have examined the conditions for plasmid persistence in bacterial populations. A limitation includes that a majority of the mathematical models for examining plasmid persistence only included bacteria from similar colonies. However, most bacterial cells inhabit complex communities where plasmids disseminate between varied bacterial host cells. Thus, there is a gap in knowledge...
Topics: Plasmid carriage, Plasmid persistence, Biofilm, Conjugation, HGT
Stress cardiomyopathy also called Takotsubo cardiomyopathy is characterized by transient regional systolic dysfunction of the left ventricle with electrocardiographic changes and an increase in troponin levels imitating myocardial infarction, but in the absence of angiographic evidence of obstructive coronary artery disease. Although the exact causal process has not been determined, it has been mentioned in connection with thyroid diseases. We describe a woman's case that experienced severe...
Topics: Hyperthiroidism, Cardiomiopathy, Takotsubo syndrome, Graves’ disease, Thyroid diseases
Aluminum phosphide (ALP) is a highly toxic compound most commonly available as Celphos in Nepal. Suicidal ingestion is common in developing countries like Nepal as it is easily available and has a high mortality rate. Farmers to protect crops from rodents and pests use it. Here we present a case of a 24-year-old female with suicidal ingestion of one and a half-tablet of ALP presented with abdominal pain and vomiting. The patient developed metabolic acidosis, hyperkalemia, acute respiratory...
Topics: Aluminum phosphide, Suicidal ingestion, Metabolic acidosis, Acute respiratory distress, Magnesium...
Brucellosis is a zoonotic disease, seen globally, especially in developing countries and it can affect many organs. Urinary involvement of this disease is a very rare. Pyelonephritis, interstitial nephritis, glomerulonephritis, nephropathy are the reported urinary involvements. In this study, we aimed to report a case of Brucella pyelonephritis, who had complaints mimicking acute bacterial pyelonephritis, with a history of polycystic kidney disease and calculi in the left kidney
Topics: Brucella, Pyelonephtiyis, Brucellosis
A diverticulum is a limited saccular protrusion of the esophageal wall, communicating with its lumen. Anatomically, esophageal diverticula are classified into pharyngoesophageal, median, and epiphrenic. Treatment of esophageal diverticula is based on several basic pathophysiological principles. Small and asymptomatic diverticula do not require specific treatment. Large and symptomatic diverticula require surgical intervention, consisting of diverticulectomy combined with myotomy. Operations for...
Topics: Epiphrenic diverticula, Lewis operation, Eventration
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Topics: Graves’ ophtalmopathy, Graves’ disease, Hyperthyroidism
Peripartum cardiomyopathy (PPCM) is a rare but life-threatening condition defined by left ventricular dysfunction and heart failure (HF), occurring in late pregnancy or, more commonly, the early postpartum period. In African American women, women with pre-eclampsia, advanced maternal age, and numerous gestation pregnancies, there is a greater incidence. Although the pathophysiology of PPCM is still undetermined, the importance of vasculo-hormonal pathways has been suggested in research over the...
Topics: Cardiomiopathy, Heart failure, Pre-eclampsia, Pregnancy
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Topics: Residency, Research, Publishing
Introduction : During COVID-19 outbreaks, disproportionate use of antibiotics, high Intensive Care Units burden and longer in-hospital stays may have aggravated the emergency posed by carbapenem-resistant isolates. Therefore, we set out to determine whether the incidence of carbapenem-resistant isolates rose in a tertiary care center in Santa Fe, Argentina during the period with active cases of COVID-19. Material and methods : In this retrospectively designed analytic epidemiologic study, two...
Topics: Carbapenem-resistant Enterobacteriaceae, Antibiotic resistance, COVID-19, SARS-CoV-2, Outbreak
Introduction : SARS-CoV-2 continues to raise health and socio-economical concerns globally. The recent discovery of the B.1.1.529 (Omicron) variant with its critical mutations has heightened the debate about the need for a better global vaccination rollout to prevent the emergence of new SARS-CoV-2 strains. Optimizing vaccine rollout in Africa is crucial for the management of the pandemic and preventing the rise of new strains. To better direct efforts and interventions it is important to know...
Topics: SARS-CoV-2, Africa, COVID-19, Vaccine, Immunology, New strains, International relations
Introduction : With the increase of COVID-19 cases, an unusual manifestation for this type of virus began to appear anosmia and dysgeusia, which could indicate a neurologic alteration. In this context, it seems likely that subclinical manifestations of baroreflex involvement occur. The vegetative nervous system carries out the regulation of the baroreflex through the balance between sympathetic and parasympathetic activity. The objective of this study is to verify whether patients with COVID-19...
Topics: Dysautonomia, COVID-19, Heart rate variability
Introduction : The hand harbors different species of bacteria that may play a role in the transmission of infectious diseases. Therefore, this study was conducted to determine the bacterial profile of hands and assess the efficacy of the three most common methods of hand cleansing on the reduction of that bacteria. Materials and methods : Hand swaps were collected from 150 adults. The identity of bacteria was done by standard microbiological procedures. Each participant applied one of three...
Topics: Hand hygiene, Handwashing, Sanitizer, Hand wipes
Introduction : During COVID-19 pandemic, when social distancing becomes compulsory for all, a nation-wide school closure was implemented. The aim of this paper is to assess the impact of COVID-19 lockdown on children with ASD and their families in Tripoli, Libya. Materials and Methods : We conducted face-to-face interviews with parents of children with Autism Spectrum Disorder (ASD) during the period of the outbreak between June to December 2020. The Modified Check list of Autism in Toddlers...
Topics: Autism, COVID-19, Behaviour, Lockdown, Libya
Antibiotic resistance is a significant issue for the medical community, worldwide. Many bacteria develop drug resistance by utilizing multidrug resistant or MDR efflux pumps that can export antibiotics from bacterial cells. Antibiotics are expelled from bacteria by efflux pumps a part of the resistance nodulation division (RND) family. Types of RND efflux pumps include the AcrAB-TolC tripartite protein pump. There are an excessive number of antibiotic compounds that have been discovered;...
Topics: Efflux pump, Antibiotic resistance, Bacterial metabolic pathways
Introduction : Urinary Tract infection (UTI) is considered as the most common infections disease among women. UTI may lead to a serious complication in both kidneys. In this study, we tried to determine whether the alternation in platelet count during UTI is related to specific Gram-type of bacteria causing the infection. This assists the medical staff in selection of suitable antimicrobial drug. Material and Methods : Data of all urine cultures from Gynecology Department/ Albaraa...
Topics: Urinary tract infection, Women, Platelet count, Bacteria, Gram-type
Introduction : Pressure ulcers (PU) are a major health problem, causing increased health costs as well as workload of health workers. In this study, we aimed to analyze the developments in PUs and to add perspective to future studies by examining the research articles published on PUs, which is an increasing health problem worldwide. Material and methods : Bibliometric analysis method was used in this study. The data was obtained by searching the Elsevier Scopus database with using the keywords...
Topics: Pressure ulcers, Bibliometric method, Scopus database
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Topics: Blood pressure, Atherothrombotic syndrome, Circadian rhythm
Introduction : Epicardial fat tissue (EFT) is a significant risk factor for cardiovascular diseases. This study aimed to investigate whether there is a relationship between the fibrosis-4 index (FIB-4 index) and EFT in newly-diagnosed hypertensive patients and explore the usability of the FIB-4 index in predicting non-dipper blood pressure (BP) pattern. Materials and methods : Our case–control study consisted of 210 patients in 3 groups according to BP values, namely normotensive, dipper, and...
Topics: Hypertension, Non-dipper, Fibrosis-4 index, Epicardial adipose tissue
Introduction : Treatment approach in COVID-19 infection consists of antiviral, immunomodulatory, and supportive treatments. Convalescent plasma, immune plasma or hyperimmune plasma refers to the plasma that consisting of high titer polyclonal antibodies against the virus and are amidst the immunomodulatory treatments. Although it has been reported that immune plasma treatment of COVID-19 reduces hospital stay and mortality, the efficacy of immune plasma with COVID-19 infection is not clear yet....
Topics: COVID-19, Immune plasma, Intensivecare unit, Mortality
Introduction : Obesity is a gradually more important multifactorial disease in both children and adults. Obese children and adolescents are at higher risk of becoming obese in adulthood, which is associated with an increased risk of mortality and morbidity. There is subclinical systemic inflammation in obesity. The study aimed to evaluate the hematological parameters as an indicator of inflammation in obese adolescents and to show the relationship of monocyte/HDL-cholesterol ratio, having a...
Topics: NLR, PLR, MLR, Monocyte/HDL-colesterol, Obesity, Adolescent
Introduction : Recent studies have shown that the intestinal microbiota can modulate certain systemic metabolic and immune responses, including liver graft function and the development of complications in patients after liver transplantation (LT). Akkermansia muciniphila (AKM) and Faecalibacterium prausnitzii (FAEP) are two of the most abundant gut commensal bacteria, with mucosa-protective and anti-inflammatory effects that are important for maintaining normal intestinal homeostasis and gut...
Topics: Akkermansia muciniphila, Faecalibacterium prausnitzii, Gut microbiota, Liver transplantation,...
Mucormycosis is rare in both immunocompromised and immunocompetent patients. A Chronic Myelomonocytic Leukaemia (CMML) is among the most aggressive and poorly understood chronic myeloid malignancies, and Mucormycosis is an uncommonly encountered clinical syndrome in immunocompromised hematology patients. Patients treated with mechanical ventilation are at a substantially higher risk for infection. Also, the patients who are using home respirator devices at high risk for mucormycosis. Patients...
Topics: Pulmonary, Mucormycosis, Home-ventilator device, Chronic myelomonocytic leukaemia
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Topics: Palatal tori, Oral torus, Oral bony exostosis, Adolescent woman
Introduction : Although infective endocarditis (IE) is rare disease, this disease has importance due to its high morbidity and mortality rates. The exact incidence is not known as it is not a reportable disease. Unlike developed countries, the disease affects the young more than the elderly in developing countries. Most of the time, the diagnosis cannot be made at the first examination and the disease is often overlooked. In order to reduce the mortality and morbidity of this disease, it is...
Topics: Infective endocarditis, Bibliometric analysis, Scopus database
Introduction : World Health Organization declared COVID-19 as a pandemic, and like any global health crisis at its beginning, need a commitment to take the necessary precautions due to its spread among people before and during the presence of vaccine or drug. This study aims to assess public opinion and practice of Libyan community in the context of the COVID-19 pandemic. Materials and methods : A cross-sectional online study was conducted among Libyans between Sep. 15th, and Oct. 29th, 2020...
Topics: Awareness, Coronavirus, COVID-19, Libyan people, Practice
Introduction : Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is spreading rapidly around the world caused serious respiratory disease leading to death, therefore vaccine is the effective way to control this pandemic. Scientists tried to produce safe and effective SARS-CoV-2 vaccines in record time and vaccination program started in December 2020. The aim of this study to determine the impact of SARS-CoV-2 vaccine on COVID-19 disease. Materials and methods : The COVID-19 cases...
Topics: Full vaccine, Total vaccine, COVID-19, SARS-CoV-2, mRNA vaccine, Vector vaccine, Inactivated virus...
Introduction : The spleen is located in the upper part of the abdominal cavity. As an organ, the spleen can have various shapes and size. Material and methods : The human spleen was studied in 273 cadavers (154 men and 119 women) who did not have diseases of the spleen. The shape of the spleen was analyzed based on splenic index, Michels classification. Results : The most common shape of the spleen in men is the elongated one. It was encountered in 79 (51.3%) cases out of 154. In women, the...
Topics: Spleen, Splenic shape, Dissection, Anatomy
Introduction : The pressure over health systems caused by the COVID-19 pandemic brought about the need to develop tools that would allow for the identification of those patients that require immediate attention. Our objective was to identify clinical and biochemical predictors of poor outcomes (PO) in a cohort of patients hospitalized due to COVID-19 in an Argentinean public hospital. Methods : Prospective cohort study conducted from March 3rd, 2020 to February 16th, 2021 in a tertiary care...
Topics: COVID-19, Pandemic, Mortality, Mechanical ventilation
Introduction : Early, high-quality cardiopulmonary resuscitation (CPR) increases survival rates in cardiac arrest. Although most cases occur at home and are witnessed, CPR is performed in few of these cases. For this reason, teaching CPR is especially important in relatives of patients with high cardiovascular risk. Therefore, the aim of this study was to demonstrate the effectiveness of the Family and Friends CPR course in the theoretical and practical learning of cardiopulmonary resuscitation...
Topics: Cardiopulmonary resuscitation, Cardiac arrest, Learning, Relatives, Cardiovascular diseases
Introduction : Inadequate exclusive breastfeeding is responsible for more than 236,000 child deaths each year and significantly increases the risk of death in infancy and childhood. While the COVID-19 Pandemic continues, this should not be a barrier for breastfeeding mothers to breastfeed their babies. This study aims to analyze the factors related to exclusive breastfeeding during the COVID-19 pandemic in the working area of the Poasia Health Center, Kendari City. Methods : This...
Topics: Exclusive breastfeeding, Parity, Family support, Helath worker support
Introduction : An ectopic pregnancy occurs when a fertilized egg attaches somewhere outside the uterus.There are many risk factors for ectopic pregnancy. This study will help us to prepare a list of risk factors associated with ectopic pregnancy in our state. In addition, it will help implement a risk-reduction counseling program before conception, which will help us screen high-risk patients and reduce and manage ectopic pregnancy. Materials and methods : The present study was conducted in our...
Topics: Ectopic pregnancy, Pelvic inflamatory disease, Risk factors
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Topics: Proton pump inhibitors, Prescription, Inadequate
Introduction : The relationship between inflammation and cancer has long been the focus of researchers' interest. There are many inflammatory markers studied for this purpose in the literature. In this context, we focused on the effects of platelet counts and platelet mass index (PMI) as inflammatory markers in the diagnosis of low-volume localized testicular cancer. Materials and methods : Thirty-eight patients with localized testicular cancer with a mean age of 30.84 ± 5.79 years and 38...
Topics: PMI, Testicular tumours, Biomarkers
Introduction : Laboratory examinations constitute a major factor in achieving the correct clinical diagnosis for patients. However, the ordering of unnecessary or inappropriate laboratory testing remains common, with consequent consumption of laboratory resources whether human or material. The present work evaluated the level of satisfaction of laboratory practitioners toward the appropriateness of laboratory tests ordered by physicians. Methods : This cross-sectional study involved a total of...
Topics: Inappropriate laboratory testing, Clinical laboratory professionals, Physicians
Introduction : This study was conducted to assess the traditional beliefs and practices in postpartum care among Indonesian and Filipino mothers to propose a program to improve maternal and child health. Methods : The study utilized a descriptive research design to Indonesian mother respondents (n=110) and Filipino mother-respondents (n=119) who were conveniently selected. Traditional beliefs focused on technological factors, religious and philosophical factors, kinship and social factors,...
Topics: Traditional, Culture, Postnatal care, Cultural diversity, Indonesia, Philippines
Introduction : Successful medical decisions are highly reliant on medical laboratory results; as such, laboratory results are essential to patient health management, and errors in those results may lead to serious complications and death. The aim of the present study was to assess the knowledge of medical laboratory practitioners in Saudi Arabia regarding factors that may influence medical laboratory testing results and the correct actions for troubleshooting. Methods : A total of 256...
Topics: Knowledge, Attitudes, Medical laboratory professionals, Non-pathological factors
Introduction : The use of tele-rehabilitation devices to aid physiotherapy has gained popularity in recent years. In particular, measuring limb range of motion with a wearable mobile sensor can facilitate rehabilitation therapies by providing more efficient progress monitoring and reducing clinicians’ workload. This study aimed to examine the test-retest reliability and validity of using a wearable mobile sensor to measure upper limb range of motion (ROM). Materials and methods : Participants...
Topics: Range of motion, Upper limb, Accelerometer, Goniometer
Introduction : Urinary tract infections (UTI) are one of the most common human bacterial infections encountered by physicians. The risk of resistant microbes is emerging as a result of the overuse of antibiotics treatments. The presence of pathogens with increased resistance to antimicrobial agents makes UTIs difficult to treat. This study was aimed at determining the prevalence of the pathogens that cause UTIs, as well as the antibiotic susceptibility of these isolates. Materials and methods :...
Topics: Antibiotic resistance pattern, Urinary tract infection, Urine culture
Introduction : There is a dearth of knowledge on the proportion that occult thyroid carcinoma constitutes amongst patients with thyroid cancer in our practice. This study was therefore conducted to review the cases of occult thyroid carcinoma with a focus on the presentation, management, and the outcome of care in a low resource tertiary hospital setting. Materials and Methods : We conducted a retrospective cross-sectional descriptive study of 62 patients who were managed for thyroid cancer...
Topics: Occult thyroid carcinoma, Papillary carcinoma, Thyroidectomy
Introduction : Biomechanical stimulation of cultured human osteoblast-like cells, which is based on controlled mechanical vibration, has been previously indicated, but the exact mechanical parameters that are effective for cells' proliferation enhancement are still elusive due to the lack of direct data recordings from the stimulated cells in culture. Therefore, we developed a low friction tunable system that enables recording of a narrow range of mechanical parameters, above the infrasonic...
Topics: Osteoblast, Mechanical stimulation, Vibration, Mechanotransduction
Introduction : Psychological stress is a common psychiatric disorder in medical students and sometimes is associated with depression. Students at university usually met a great pressure that they face in their study life and to the hard circumstances in the everyday life. The aim of this study is to estimate the prevalence of depression and stress among university medical students in Libya. Materials and methods : Data was collected by three different questionnaires: the first questionnaire is...
Topics: Anxiety, Depression, Libya, Medical students, Screening, Stress
Introduction : There are very few studies on the effects of regular blood transfusions on the hemodynamic organization of patients with Beta-Thalassemia Major (BTM). Ambulatory Blood Pressure Monitoring is method that evaluates fluctuations in day-night periods and life cycle changes. In this study, we aimed to investigate the effects of blood transfusion on hemodynamic parameters by the Ambulatory Blood Pressure Monitoring method on the day of transfusion in patients with a diagnosis of...
Topics: Non-dipper, Thalassemia, Transfusion, Blood pressure
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Topics: Left-sided gallbladder, Laparoscopic cholecystectomy, Anatomy
The anatomy of the first vertebra, namely atlas, has significant clinical implications. Atlas is situated between the occipital bone and the second cervical vertebra (axis) and is one of the main points of head movement. Most congenital anomalies of the vertebra are diagnosed incidentally during imaging investigations and can be associated with cervical spine anomalies. The neurological symptoms may include weakness in the four limbs, acute neurologic deficits such as transient quadriparesis,...
Topics: Developmental defect, First cervical vertebra, Anatomy
Persistent urogenital sinus (PUGS) is an uncommon developmental cloacal anomaly, with Incidence of 0.6 in 10000 female births. Herein we depict the case of a 22-year of age lady who presented with Infertility for 16 months with dyspareunia and was found to have Persistent urogenital sinus associated with other urogenital anomalies as unilateral rudimentary horn with ipsilateral renal agenesis and contralateral dermoid cyst. The patient was successfully treated with the excision of the sinus,...
Topics: Urogenital sinus, Renal agenesis, Rudimentary horn
Presentation of botulism in adults is extremely rare and symptoms can be easily confused for symptoms of acute stroke, Guillain-Barre, or myasthenia gravis. The purpose of this clinical case report is to ensure adult botulism will be included in the differential diagnoses for a patient with this presentation so swift and accurate care can be provided to ensure optimal patient outcome. A 41-year-old-female presented with complaints of sudden onset of difficulty speaking. The patient reports a...
Topics: Botulism, Botulism antitoxin, Differential diagnosis, Pharmaceutical preparations, Humans, Aftercare
Streptococcus agalactiae ( S. agalactiae ) is a microorganism that asymptomatically colonizes the female genital and gastrointestinal tracts of humans. It produces infections in extreme ages of life and in pregnant women. The case of an adult male is presented, with frequent heterosexual intercourse with different partners. He consulted for itching and burning in the penis' glans. His partner had marked vaginal dryness as a result of early ovarian failure. The patient had ulcerative,...
Topics: Streptococcus, Streptococcus agalactiae, Genitalia male, Penile diseases, Reproductive tract...
Recently, an upsurge in the incidence of several emerging infectious diseases is causing great challenges to the health professionals throughout the globe. Since early 2020, an outbreak of coronavirus disease 2019 (COVID-19), now a pandemic, is hitting the world severely. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causative agent of COVID-19, gain entry through the respiratory systems (nasopharyngeal) route causing infection. This disease is reported from all continents...
Topics: Coronavirus, COVID-19, Emerging infectious disease, Public health, RT-PCR, SARS-CoV-2
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Topics: SARS-CoV-2, Diagnosis, Hygiene
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Topics: Oncology, Clinical Oncology, Advances
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Topics: Telemedicine, COVID-19, Children, Pediatrics, Neurology
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Topics: Evidence-Based practice, Scientific studies, Medicine, Physycal therapy, Allied health
Change is a learning process modeling the attitudes and values of the involved staff to adapt and show the change in daily work life. Leading the change in medical schools or in the health care system is considered one of the assignments of successful leadership that can achieve an effective organizational change under complex conditions. This review aims to show an implementation view about how to manage the change in medical institutions and how to overcome obstacles, and how to face the...
Topics: Change, Management, Implementation, Medical institutions
During December 2019, a rapid increase in the number of SARS-CoV-2 (COVID-19) cases was reported worldwide. We investigated several factors for rapid increase in SARS-COV-2. Genomic sequence reveals that domestic and wild animals were likely ancestors and zoonotic source for SARS-CoVs, MERS-CoVs, and SARS-CoV-2; these viruses replicated in animals and humans during past several decades, exhibiting diverse mutations and self-limiting diseases except during outbreaks. SARS-CoV-2 has been...
Topics: SARS-CoV-2, RT-PCR, Antibody, Zoonotic, Animal transmission, Genomics, Asymptomatic fraction, Herd...
The relationship between the intra-abdominal pressure (IAP) and intracranial pressure (ICP) has been suspected for more than 100 years and was subsequently confirmed by numerous studies in both animals and humans which demonstrate the link and the positive correlation between IAP and ICP. There are mounting concerns that the pneumoperitoneum created during laparoscopic surgery to create space for instrument placement and to allow safe tissue dissection may result in an increase in the ICP...
Topics: Laparoscopy, Surgery, Ventriculoperitoneal shunts, Safety
The COVID-19 pandemic and the limited therapeutic arsenal available strain daily clinical practice. Guidelines have recently recommended routine anticoagulation of hospitalized COVID-19 patients. However, apart from the expert panels’ experience, the provenance of this recommendation is not clear, due to the scarce published evidence. We provide a narrative review with the objective of unraveling the rationale for this practice. First, we analyze the biochemical, histopathological and...
Topics: COVID-19, SARS-CoV-2, Thrombosis, Anticoagulation
Introduction : Diabetes mellitus is a chronic metabolic disorder that induces elevated plasma glucose levels. Diabetic patients are more susceptible to infections, especially fungal infections. There is a direct relationship between increased blood glucose levels and the number of Candida hyphae in the oral mucosa. This study aimed to evaluate oral candidiasis and the different Candida species found in patients with and without diabetes mellitus. Methods : A search for studies on oral...
Topics: Blood glucose, Oral candidiasis, Diabetes mellitus, Risk factors
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Topics: Skin diseases, Hyperpigmentation, Asymptomatic hyperpigmented macules, Acquired macular...
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Topics: Polycystic liver disease, Autosomal dominant polycystic liver disease, Liver cysts
Introduction : In mechanically ventilated patients, ventilator-associated pneumonia (VAP) is a major cause of prolonged hospitalization with increased morbidity and mortality. There is a lack of studies on the relationship between bacterial colonization of the ventilator circuit (VC) and VAP. This study aimed to investigate the role of bacterial colonization of VC in the development of VAP and identify antibiotic susceptibility trends for isolated strains. Methods : A prospective study of the...
Topics: Ventilator circuit, Bacterial colonization, Antibiotic resistance, Intensive care unit
Introduction : Tuberculosis infection caused by Mycobacterium tuberculosis is one of the most common infectious diseases, especially in countries such as Iran. The course of treatment and the number of drugs used vary depending on the severity of the disease and the parts of the body involved. The resistant tuberculosis to treatment has increased in recent years. Thus, this study was conducted to investigate the frequency distribution of response to treatment of patients with tuberculosis in...
Topics: Mycobacterium tuberculosis, Resistant tuberculosis, Treatment
Retinitis pigmentosa (RP) or hereditary retinal dystrophy is a rare disease that can be isolated (non-syndromic RP) or associated with other systemic signs (syndromic RP). Kidney damage is exceptionally reported in patients with RP, particularly in syndromic forms. Association with renal amyloidosis remains unusual with only one reported case of RP and hereditary gelsolin amyloidosis due to a G654A gelsolin mutation defining the new syndrome of Ardalan-Shoja-Kiuru. Apart from this publication,...
Topics: Retinitis pigmentosa, Light chain amyloidosis, AL amyloidosis, Primary amyloidosis
Introduction : Oral and dental (OD) disorders in children with Rubinstein-Taybi syndrome (RTS) are frequent but not well-known by dentists and pediatricians due to the syndrome being extremely rare. Objective : To describe the OD findings observed in a 5-year-old girl with RTS and to update the literature. Clinical case : The patient presented the following OD manifestations: prominent lower lip, narrow mouth opening, narrow and arched palate, history of angular cheilitis, micrognathia, poor...
Topics: Rubinstein-Taybi syndrome, Odontostomatology disorders, Pediatric dentistry, Disabled persons,...
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Topics: Pseudo prune belly syndrome, Abdominal wall laxity, Female
Varicella Zoster (shingles) virus is a double stranded DNA in the Herpesviridae family that can present as both chicken pox and as shingles. The virus enters through the respiratory system, replicating in the nasopharynx, and causes a viremia upon primary infection. Varicella Zoster spreads to other organs and often lies dormant in the dorsal root ganglion. Reactivation of the virus is more common in older or immunocompromised patients and often presents as a painful vesicular rash in a...
Topics: Varicella zoster virus, Shingles, Urinary dysfunction
Introduction : Conflicting evidences exist that ABO blood groups correlate with the susceptibility to COVID-19 and its clinical outcomes. This study aimed to pool available articles that assessed a possible relationship between COVID-19 and ABO blood groups. Materials and methods : A search was conducted in four databases comprising Pubmed/Medline, Google scholar, Journal storage (JSTOR) and African Journals Online (AJOL) for relevant studies available before 25th August 2020 and contained...
Topics: ABO blood group, Susceptibility, Severity, Mortality, COVID-19, SARS-COV-2
Central precocious puberty (CPP) is a rare disease. The mean annual incidence in girls is 0.8-1.1/100,000 and in boys 0-0.1/100,000. Intracranial arachnoid cysts (ICACs) are usually congenital and represent 1% of intracranial masses in newborns. Intraventricular location is rare. The objective of this work is to carry out a literature updated review of the coexistence of CPP and intraventricular arachnoid cyst (IVAC). ICACs are usually asymptomatic but can present with CPP in 10-40% of...
Topics: Central precocious puberty, Intraventricular arachnoid cyst, Children, Rare diseases, GnRH test,...
Neurological disorders present a major group of diseases with the global prevalence of 6.3%. They are responsible for 12% global mortality. Mast cells are one of the most abundantly present cell of the immune system in the connective tissue and the central nervous system is not an exception. In this article is presented a review of studies on mast cells regarding their physiological role in cental nervous system. We also disscuss their role in several conditions like: multiple sclerosis,...
Topics: Central nervous system, Neuroimmunology, Mast cells, Histamine
The Objective Structured Clinical Examination (OSCE) is considered a gold standard summative and formative assessment method wherein it is a comprehensive and standardized tool assessing the clinical competencies including psychomotor domain, attitudes, and behaviors that will be manifested in the real work of the medical graduates. Therefore, the implementation of OSCE depends on the design of a blueprint that consists of two axes; the first axis is the tested competencies according to the...
Topics: Objective structured clinical examination, Educational assessment, Medical education, Clinical...
Introduction : Allergic conjunctivitis is treated with oral anti-allergy agents or topical eye drops, but the response is often incomplete, and symptoms persist. We considered that topical treatment with an antihistamine ointment (diphenhydramine-Restamin Cream®) on the eyelids could be effective as supplemental therapy. This study investigates the efficacy and safety of Restamin Cream® for allergic conjunctivitis. Methods : In patients with allergic conjunctivitis, Restamin Cream® was...
Topics: Allergic, Conjunctivitis, Antihistamines, Asthma, Conjunctiva, Topical administration
Introduction : Progranulin or acrogranin is an 88-kDa glycoprotein identified by a biological screen for protein targets associated with high tumorigenicity. This work was aimed to investigate the digital expression of GP88, and HER2/neu as a predictive biomarker in human invasive ductal carcinoma (IDC) versus benign tumors and normal breast tissues, as well as its correlation with different pathological parameters. Methods : The immunohistochemical avidin-biotin complex protocol of the...
Topics: HER2/neu, GP88, Clinical pathological parameter, Invasive ductal carcinoma, Immunohistochemical...
Introduction : Phosphoinositides play a key role in the regulation of focal adhesions (FAs) turnover during cell adhesion and migration. However, their potential role in FA turnover at leading and trailing edge of cell are not yet fully understood. In this study, we investigate their spatial co-localisation with paxillin directly at leading and trailing edge of MDA-MB-231 breast cancer cell line. Materials and methods : Cell lines and cell culture experiments were done using MDA-MB-231human...
Topics: PtdIns(4, 5)P2, PtdIns(3, 4, 5)P3, Focal adhesions, Spatial co-localistion
Introduction : Diabetic peripheral neuropathy (DPN), a common and troublesome complication of diabetes mellitus (DM), leads to a higher risk of diabetic foot ulcers and lower limb amputation. This study aimed to assess the prevalence of DPN among patients of type 2 DM from rural North India and associated risk factors for the condition. Materials and Methods : A facility-based cross-sectional study was carried out among type 2 diabetic patients attending the Non-Communicable Diseases (NCD)...
Topics: Diabetes, Neuropathy, MNSI, Rural, North India
Introduction : Alternating and pulsed electromagnetic magnetic fields (AEMF and PEMF) of different amplitudes and frequencies can induce metabolic and proliferative effects in osteoblasts, but there is no clearly directed tendency of these effects. I hypothesize that there are extremely low triggering parameters of alternating electromagnetic field (EMF) intensity, i.e., above the background magnetic field on earth but below the lowest AEMF and PEMF that have been investigated to date (above...
Topics: Cell maturation, Cell proliferation, Electromagnetic field, Osteoblast, PEMF
Introduction : Dentin hypersensitivity (DH) is the most common concern faced by most dentists in their day-to-day clinical practice. It is characterized by short-term, acute pain of variable intensity, which occurs in response to thermal, tactile, osmotic or chemical stimuli that cannot be attributed to any other type of defect or dental decay. Casein phosphopeptide varnish is a newer material used to treat dentinal hypersensitivity as it reduces demineralization and promotes remineralization....
Topics: Casein phosphopeptide, Dentin hypersensitivity, Fluoride varnish, Visual analogue scale
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