63 pages. Includes bibliography. Evidence-based Resource Guide Series. Burnout is a complex issue resulting from chronic workplace stress that encompasses exhaustion, depersonalization, and reduced personal accomplishment. This guide highlights organization-level interventions to prevent and reduce burnout among behavioral health workers. It outlines broad lessons learned from previous studies investigating the complex causes and mediators of burnout, focusing on the domains of workload, control, reward, community, fairness, and values. It provides examples of organizations implementing organization-level strategies to address burnout with the healthcare landscape.