2 pages. September 2022. Evidence-Based Resource Guide Series. Includes bibliography. Tailoring care, programs, and services to the cultural, social, gender, and other demographic contexts of individuals served yields positive outcomes. Communities and individuals benefit when they receive behavioral health services that are clinically proven effective, equitable, and culturally appropriate. This guide describes various types of cultural adaptations of EBPs for under- resourced populations and the multiple steps in the adaptation process. The guide also focuses on research supporting such adaptations. The guide does not focus on a sole behavioral health outcome or a specific under-resourced population. Instead, it details the adaptation process practitioners can tailor and implement for their individual programs. This guide is intended to be broad and provide information for practitioners across both the mental health and substance use disorder fields. On the care continuum, this guide focuses predominantly on adapting treatment EBPs, although the adaptation process that this guide describes is applicable to any EBP in behavioral health, including prevention, treatment, and recovery practices for substance use and mental health.