meg: that's great. the three of you seem super passionate about your brand, but what's the largest order you've ever done? pantelis: um, 7,000 bars. meg: 7,000 is less than two ships. pantelis: okay. meg: so, when i think about that, i think, "okay, maybe not a fit for global fulfillment and distribution based on the conversation we've had." damom, look!get sare you okay?? head home this holiday with the one you love. visit your local mercedes-benz dealer today for exceptional lease and financing offers at the mercedes-benz winter event. see yourself. welcome back to the mirror. and know you're not alone because this is not just a mirror. it's an unstoppable community. come on jessie one more. it's a race across time zones. come on you two, lets go. a gift for the whole family. so join in now and see your best self in the mirror. ♪ when they're sick, they get comfortable all kinds of places. they also spread all kinds of germs, from cold and flu to strep and more. nothing kills more cold and flu virus

let's go to meg tirrell for who will be first in line to be vaccinated meg? >> john, this is a really big day. the cdc advisory committee is going to take its first official vote this afternoon for who is going to be at the tippy top of the list once they are cleared by the fda this is an outside group of advisers this began just now at 2:00 and they're going to be discussing this allocation and these priorities until just before 5:00 when they are going to take that vote. really this is phase 1a, just who will get those first doses of course at the beginning, supply of these vaccines will be incredibly limited the first shipment of pfizer's vaccine will be 6.4 million doses. and pfizer and moderna's together will have enough doses for 20 million in december and 25 to 30 million per month starting next year for that reason they have to choose who is at the top of the list the cdc has laid out essentially four groups who are really priorities for them. in that is of course health care personnel. there are 21 million americans in that group. adults over 65, the

first, cnbc's meg tirrell. meg, how significant will it be to have not one, but two vaccines out there >> well, shep, it's a scientific feat that has never been accomplished before in history work only began on these vaccines in mid-january when the genetic sequence of this new virus was published. now not one, but two vaccines have shattered every record for the pace of development. >> when this is over, which it will be over, we're going to look back and say it was science that got us out of this, pure science. >> now, after the fda's decision, an advisory group to the cdc meets this weekend to vote on whether to recommend moderna's vaccine. with its supply combined with pfizer's, as many as 20 million americans could receive their first shot by the end of the year that would almost cover everyone in the top priority groups, health care workers and residents of long-term care facilities that same cdc group will also vote this weekend on who should be next in line. one framework that's discussed would give pri

hi, meg? >> kelly, just got an update from operation warp speed on how all of of this is going across the country. the distribution has gone incredibly well with pfizer overall. the first boxes of vaccines were packed up and started to get shipped out from pfizer's plant in kalamazoo, michigan h.yunderstand now from general perna say 50,000 vaccines have been packed. the general is saying the vaccines should arrive in every location by 2:00 p.m. local time. tomorrow we're expecting 425 locations to get their vaccines, 66 on wednesday and an additional 581 from thursday and beyond for a total of 2.9 million doses from pfizer and biontech going out this week. the general was asked on this briefing what could go wrong with all of the deliveries here, and he was very candid. he note there had could be address mix-ups, that their technology is delicate and needs to be formatted perfectly. he said on the end of the spectrum scary things like transportation accidents could happen and the weather that

meg, thank you meg tirrell. >>> coming up, stressed out. m & t bank ceo on why they had to raise tirhe buffer on the latest stress test what that means when we're back in 90 seconds. we want both - we want a hybrid. so do banks. that's why they're going hybrid with ibm. a hybrid cloud approach helps them personalize experiences with watson ai while helping keep data secure. ♪ ♪ from banking to manufacturing, businesses are going with a smarter hybrid cloud, using the tools, platform and expertise of ibm. ♪ ♪ key corp region financial and fifth third bank on the heels of last week's stress test results with the fed announcing it will allow share buy banks to resume in q1 of 2021. one bank seeing attention is m & t bank some analysts calling them a negative standout. joining us now to talk about that and a whole lot more, in a cnbc exclusive, rene jones great to have you here again what's the takeaway? why are analysts saying m & t didn't do as well because of some of your real estate exposure to the rest of the banks? >> thanks, sara

meg? >> this coming in in the last seconds or minutes it was voted 13-1 that the top group in prioritization for the vaccine should include health care workers and residents of long-term care facilities. there are about 3 million in that group and in the health care group there are 21 million and they are the front line of the pandemic since there will be such limited it vaccines to begin with, that's why they had to talk about it there should be 20 million doses available in the month of december so that won't completely carry that health care group and long-term care facilities, so you will have to decide from that so that is the top of the list health care workers and people living in long-term care facilities >> 20 million, that means 20 million times two. so 20 million can receive the two full-shot dose of the vaccine and after it is allocated on the federal level, then is it you have to state to allocate to hospitals and nursing homes and from there to the sub group? >> the way it is

meg, thanks. let's get to ylan mui now with the latest departments out of washington on a covid relief bill your power is okay where you are? you got your lights and everything, you look fine. >> my power is okay and hopefully this power lasts all the way throughmidnight becaus that is when the government runs out of money but congress has yet to reach a deal on another covid relief package. there is still no agreement on a comprehensive spending bill. and republicans and democrats don't even see eye to eye on whether to pass a stopgap understand funding measure or how long it should last. mitch mcconnell publicly predicted yesterday that congress would be in session this weekend and he even started setting up confirmation votes for judges to help fill the time until they reach a deal >> we must not slide into treating these talks like routine negotiations to be conducted at congress routine pace so we need to complete this work and we need to completeit righ away >> but the process for passing th

recognize meg tirrell for her many reports on the coronavirus pandemic. go the-to reporter and the best report on this subject on all of cable tv i found out yesterday from her tweets that she starts her day at 6:00 a.m. i also know she's on the job during the 7:00 p.m. hour, seen her on shep's show, that's a long 14-hour day if possible and appropriate you could forward this email to her supervisor and other higherups, too. they need to know that loyal cnbc viewers appreciate your hard work and excellent reporting so i figured i would do one better and read it out on air for you. >> reporter: that's, really nice you guys make the 14-hour day feel short. >> no, you are the best. are you a rock star. it's been a big year meg, thank you so much. >>> let's turn back to the market now where stocks are higher with the s&p on pace to break its longest losing streak in three months, wow bank of america though is warning that this market is flashing a sell signal because investors, they say, are going all in according to their december global fund manager survey,

cnbc's meg tirrell starts us off tonight. meg? tonight. meg? >> hey, shep >> hey, shep well, that second covid-19 vaccine showed 95% efficacy in preventing the disease is making its way through the fda. this one from moderna.m moderna. one of the key moments in this process happened today the agency one of the key moments in this process happened today the agency released pages of its own analysis of the vaccine's safety and how well it works one surprising finding, new results from moderna suggest the vaccine could not only prevent you from getting sick with symptoms but may also stop infection as well, meaning it could cut down could cut down on transmission of the virus and on safety, the fda noted there were no severe allergic reactions to the shot. important, as those were observed in two health care workers in the uk who received pfizer/biontech's vaccine last week the most common were pain at the injection site, fatigue and muscle pain. the injection site, fatigue and the advisers meet thursday and if they vote yes the fda could offer it

meg thank you for this report. we'll be seeing you in just a little bit with an interview with pfizer's ceo coming up at 8:00 a.m. this morning. becky? >>> in the meantime, senior white house staff members were scheduled to be among the first to receive the vaccine but president trump tweeted last night that people working in the white house should receive it somewhat later in the program. he said he asked for that adjustment to be made. officials said earlier that vaccinations would be offered soon to leaders in all three branchs of government, which caused a lot of concern among people, why weren't they waiting for their turn in line, follow the cdc guidelines. my take is if you want to prove you're essential personnel, why don't you do something in washington and pass some aid. aid for americans suffering right now. whether that would be people who could be evicted soon, people who aren't working and don't have extended jobless benefits, small businesses up against the break. if you want to prove you're essentia

cbs' meg oliver leads us off in new york city. good evening, meg. >> reporter: mar >> reporter: margaret, good evening. with just two days left in 2020, just over half the number of doses the trump administration said would arrive by the end of the year have shipped, something president-elect joe biden vows to change. >> this is going to be the greatest operational challenge we've ever faced as a nation. reporter: president-electct biden says his incoming biden says his incoming administration will move heaven and earth to get the vaccination effort back on track. >> it will take ramping up to one million shots a day. >> reporter: biden gave few details about how his administration will hit that mark, but said he will invoke the defense production act to accelerate needed supplies for vaccines. he called the recently passed $900 billion covid relief bill a down payment for controlling the pandemic. earlier today, vice president- elect kamala harris received her shot... uscheers and applause ) ...as thousands of vulnerable senior c

good evening, meg. >> reporter: margaret, good evening. this new strain of the virus is 50% more infectious than the highly contagious virus we've already been dealing with this year. already been dealing wit tonight, there is evidence this strain has already been spreading across the country. tonight, concern turns to reality. >> we were informed that this new variant, that we have identified obviously from the united kingdom, has been identified here in the state of california. >> reporter: that word from governor newsom, in a talk with dr. anthony fauci. >> well, governor, first of all i'm not surprised that you have a case, and likely more cases, in california. and we likely will be seeing reports from other states. >> reporter: two cases have also shown up in colorado. >> both of these cases are colorado national guard personnel who were deployed to support staffing at the good samaritan society nursing home. >> reporter: tonight, the c.d.c. saying there's no evidence that the new strain is deadlier or resistant to the vaccine, and th

>> brennan: meg oliver, thank you. tonight the c.d.c. says more than 12.4 million doses have been delivered to the states, but at least 11 states have administered fewer than 20% of the doses available to them. cbs's manuel bojorquez has more on the slow roll-out. >> reporter: today, the chief advisor for operation warp speed acknowledged the government will not come close to its goal of giving first doses of the vaccine to 20 million americans by year's end. >> we agreed that that number is lower than what we hoped for. >> reporter: in fact, the c.d.c. puts it at only 2.6 million vaccinated so far, a lag officials blame in part on the complicated logistics of getting the shots to residents at long- term care facilities. there are other challenges for distributors. >> it's been just 12 days, there there's two holidays and then they work through three major snow storms in the last two weeks. and still really a remarkable job. >> reporter: florida's governor bypassed c.d.c. guidelines and opened vaccinations to anyone over 65, citing conce

meg tirrell is here on how the country got a head start meg? >> reporter: they shower did, kelly. this is a world first, the first covid-19 vaccine being cleared by a government or completing phase three clinical trials. so as you said these doses will start to go out in the uk next week we're hearing about 800,000 doses in that first shipment that's of a total 40 million that pfizer and biontech have agreed to supply to the uk this year and next year operation warp speed here in the u.s. is holding a briefing right now, and the chief adviser to that effort was talking about this uk approval process really saying this is a gold standard agency who reviewed this and making a comment about how he hopes americans will take this clearance. here's what he said. >> they have not been part or involved in any of the politicization that surrounded the development of this vaccine, and i hope this will be another evidence for the american population that the data with these vaccines are clear, are transparent and demonstrate that they are effective and safe for use in the general population.

still up more than 65% from its ipo price of 102 and we're waiting pfizer and biontech let's get to meg tirrell for more on that story hi, meg. >> hi, kelly while we are expecting the fda to issue emergency use authorization, really at any point now after this positive vote from its advisory committee last night, here's the timeline of what we're looking for in the coming days. so the fda is working now essentially on that emergency use authorization. today and over the weekend an outside group of advisers to the cdc is meeting to discuss the vaccine and will vote to give its recommendation for that specific vaccine after the fda gives its green light and then within 24 hours of that emergency use authorization, it expected that 3 million doses are going to start to ship across the u.s how do we know the fda will act sunday with this eua it put out an unusual statement this morning saying it's informed pfizer that it will rapidly work toward finalization andish you issuance of an emerge authorization. yesterday the vote was 17 votes in favor, four votes again and one vote -- one person

. >> thank you very much let's get to meg tirrell she has breaking news on pfizer. meg? >> hi, scott a state just coming out from pfizer about its covid-19 production they're saying they are trying to address public comments that allege there are issues of production and distribution of the company's vaccine. saying, quote, feis ser not having any issues with our vaccine, no shipments are on homemade or delayed. they say we have millions more doses sitting in our warehouse but have not received any additional instructions for doses. we've been hearing from states that their allotments may have been cut, four states saying 30%. florida's governor ron desantis said their next shipment is on hold and pfizer said they have no shipment issues if moderna's gets authorized, 5.9 million doses will go out next week. we've been hearing there should be enough vaccine for 20 million people within december operation warp speed has put that out there and an hes spokesperson tells me that is still the plan florida saying it's because of production issues and pfizer says that is not the

the catch the chinese telecom executive would have to admit to criminal wrongdoing something meg may be reluctant to do saying that she's maintained her innocence throughout the process meanwhile china has kept up the pressure on canada to release as soon as possible regardless of what the u.s. justice department has to say. without violating any canadian laws and has been under reasonably detain so far we express our strong indignation and condemnation on this account since the arrest china has punished canada through trade restrictions and allegedly through the arrest of 2 canadians it is a popular belief that michael covel former diplomat and michael spouse or an autopen or were arrested and charged with spying in china in retaliation for megs arrest in vancouver claiming that they suggesting that these are just going on. raising this spike charge a charge me. instantly to keep pressing the issue we're seeing. with the possibility of men being released there is hope that the process could open the door for the 2 imprisoned canadians as well according to the globe and mail source t

. >> meg, it's going to be a fascinating rollout. logistics are key. our meg tirrell on pfizer's historic day today. >>> the m&a announced change is all around us. shaped by technology and human ingenuity, we can make it work for you and your business. ♪ help the world believe in holiday magic.thing and this year was harder than ever. and yet, somehow, you all found a way to pull it off. it's not about the toys or the ornaments but about coming together. santa, santa, you're on mute! just wanted to say thanks. thanks for believing. >>> as we have been saying, a fizz busy day. a plethora of deals. the biggest announced on saturday the giant pharma deal $30 billion which is what it was worth when it was announced. astrazeneca's stock price might not be quite worth that but you can see shares of alexion are up and entering a definitive agreement in which astrazeneca will be buying alexi ooon. american depository shares and, again, we will keep an eye on those because they did appear to be down as much as 6%. no real overlap between th

meg tirrell has the latest developments meg, like joe said, there is a lot to analyze here. >> there sure is i mean this was a nine hour long meeting with finally that vote at the end of the day. ultimately it did come down to 17 yes votes, four no votes, one abstention off weoverwhelmingly positive. normally they explain their votes, but this one had run so long that they ended it abruptly and some sxwres xpressed frustrn because they couldn't explain their vote and this is the last step before the fda needs to make their decision and so at least for two of the panelists, it was about the question that was asked. essentially do the benefits of the pfizer/biontech vaccine outweigh risks for individuals 16 years or older. and it was the age question. dr. david kim from the department of health and human services who is one of the no votes told us, i would have voted yes most enthusiastically had the language been 18 years of age and older one of the questions really was pfizer had extended it down in the trial after it started the trial. and so there was debate about whether there wer

meg, thank you, appreciate it. we will of course follow this and be talking to you i'm sure all day long meantime, uber's autonomous shift. the company selling its self-driving unit. we're going to be joined exclusively by the ceos of both companies in a little bit. >>> live with the ceo of america's largest pension fund, to talk market euphoria, esg and so much else and another big story about why she's decided to work with the vatican on a more inclusive approach to capitalism stay tuned, you're watching "squawk box" right here on cnbc. >>> tesla announcing it plans to sell $5 billion in stock at market prices from its words, from time to time, that coming in an s.e.c. filing. it's the second stock sale announcement from tesla in three months and the third this year as the company takes advantage of the big surge in its stock price in 2020 andrew >> thanks, joe we heard earlier in the show about a new alliance of business leaders that will be working with the pope, and the vatican and aiming for more equity susta

meg tirrell, thank you. >>> as meg mentioned officials from the fda due to meet this thursday to review pfizer's coronavirus vaccine it developed with biontech and it could receive authorization almost immediately. this as the uk will begin their rollout of the pfizer vaccine tomorrow joining us now dr. jane henny who served as the fda commissioner from 1998 to 2001 these currently on the board of amerisource bergen what will you be looking for this week as we perhaps do paperwork tomorrow and await a decision by thursday >> it is going to be a very interesting week as this advisory board meets fda convenes, advisory set up -- there are people that represent a wide array of expertise to deal with the product in question in this case, a vaccine. there also are always emma member of industry and a consumer representative on these advisory committees. and what they are asked to do by the agency is two things one, listen to the company's presentation of their analysis of the data. and the fda has provided all of the raw data by the company as well they undertake the scientists and clinics a

cnbc's meg terrell with the news for us meg, what have you learned >> we're hearing this deal could be announced as soon as tomorrow 1 100 million additional doses of pfizer's vaccine the understanding is 70 million doses could be delivered in the second quarter that would be split evenly across april, may and june 30 million doses potentially in the third quarter, according to people familiar with the situation. and now "the new york times" which broke the news earlier reported the defense production act could potentially be used to speed those 30 million doses for delivery into the second quarter. so we will have to see when those can be delivered but this significantly adds to the supply for the united states of coronavirus vaccines. we know moderna has reached a deal with the u.s. for 200 million doses. this would add to the 100 million from pfizer already. that's enough for up to 200 million people by the middle of next year. we know that's not enough for everybody in america, they are counting on vaccines potentially from j & j and astrazeneca coming in next year. >> the potentia

meg terrell has that meg? >> carl, so this just coming out of a cdc briefing now and it was expected the cdc is now issuing new guidelines for how long people need to quarantine after possible exposure to covid-19. they still recommend 14 days as the absolute safest way to ensure that you're not going to spread covid-19, but they are now saying if people don't have symptoms, after ten days they could end their quarantine, or if they get a negative test and they have no symptoms, they could end the quarantine after seven days so this is updated guidance and really the goal is to try to help more people be able to quarantine for at least some period of time they have done the modelling on this and found that the risk is low at these time periods. they said after ten days the residual risk of being able to pass this along is about 1%. so the risk is not zero and they are still recommending 14 days if people can do it, but if ten or seven is preferable, getting a test at seven will allow you to end your quarantine

meg, thanks for now. always appreciate it meg tirrell for us pfizer up 3% and biontech as well is this a sell the news kind of event for vaccines names with big runs joining me is a senior analyst at bernstein ronny, great to have you back. are you recommending that people take some profits here >> so, what i'm basically saying is that what it looks like more than anything else is we have an earlier wave of vaccinations in the united states. most people think it will be around mid-year and it now looks that we've had a significant amount of vaccination in the first quarter and once you pass roughly 50%, we can see the epidemic plummet so the argument is that the stock that they should perform on thisnews are the stock that are part of the reopening trades so like the hotels, airlines and my colleagues just upgraded this morning. less so if the drug companies which are probably more funds for the trade. the stocks are seeing a little bit of pressure from the nominees that the biden administration is puttin

breaking news on moderna meg tirrell has got it for us. hey, meg >> hey, wilf well, the u.s. government has exercised its option to purchase an additional 100 million doses of moderna's covid-19 vaccine for delivery in the second quarter of next year now of course the government had already purchased 100 million doses. moderna says that 20 million of those doses will be delivered by the end of december, 2020, as expected the balance will be delivered in the first quarter of 2021. and then this additional 100 million doses would come in the second quarter by june of 2021 of course all of this contingent on this vaccine getting emergency use authorization from the fda, which could come after its meeting on thursday of next week guys, of course the context of this is the stories that have been swirling about pfizer having offered its second quarter allotment of its vaccine to the u.s. government before then selling it to other governments and concern that we would reach a gap in availability of vaccine next year so the government striking this deal with moderna now saying that t

meg tirrell, tell us the truth well, hey, andrew. so this "wall street journal" story really explaining a change that happened between september and november for 2020 supply of its covid-19 vaccine as recently as september they were forecasting 140 million doses could be available this year, and then as of november, they reduced that to 50 million doses. they're still projecting 1.3 billion doses being available globally explaining it was an issue with their raw materials but pfizer saying it's confident in its ability to ship, you know, 50 million in 2020, and 1.3 billion in 2021. similarly, moncef slaoui from operation warp speed telling us there's no change to pfizer's commitment and he hasn't been informed of issues this isn't a current problem but explaining something that happened at least a month ago. now, we are a week away from potentially seeing the first doses going out in the united states, depending on how quickly the fda acts, and operation warp speed has said that the initial doses available from pfizer in the first ba

meg tirrell with a closer look at the regulatory process. meg? >> sara, we could just be hours away from the second vote from an advisory committee to the fda supporting authorization of a covid-19 vaccine they are currently in discussions now. they have done presentations from the fda this morning on the company's data the company has presented. they are taking questions from the committee. and that voting is expected to happen sometime between 3:15 and 5:15 we will bring the results of that vote. last week the same panel met on the pfizer/biontech vaccine and they were talking at least in terms of any dissent about the age involved there, 16-plus for that emergency use authorization. for moderna it is 18 plus. we don't except that to bea hiccup if they vote this afternoon, the fda could issue its emergency use authorization tomorrow or saturday then doses would go out across the united states on top of the pfizer/biontech vaccine that started going out this week. some of the conversation among the panel members today include the alernlic reacti

the united states is not one of them cnbc's meg tirrell now meg, what do we know about this new covid strain should any of us be concerned? >> reporter: so, shep, we know that it's been detected at greater and greater frequency across the u.k. beings and we've also seen cases in that country take off over the last few weeks. the u.k. of course went into lockdown for most of november and significantly decreased its number of new daily cases, but they sprang up quickly again once those measures were lifted. the variant has also now been detected in denmark, italy, the netherlands and australia in two travelers from the u.k u.k. scientists suggested the variant makes the virus 50% more trans missable, perhaps through mu tigss that make it better at infecting cells but no sign it makes the disease worse. of course, there could be other factors at work. >> this could also be explained by different behaviors people are relaxing the precautions that they're taking that are intended to reduce transmission that could also potentially explain the uptick >> reporter: the key question, of course,

here to help us get to the bottom of it we welcome our own meg tirrell along with d dr. jawad, associate professor of medicine at the university of pittsburgh welcome to boast you meg, let's just start with what we know at this hour about why these states are finding their expectations and their supplies cut. >> reporter: well, we're getting sort of conflicting messages really out of the administration they note bottom line they still expect 20 million people to be able to get their first shot within december assuming that the pfizer -- the moderna vaccine gets emergency use authorization today or tomorrow as everybody expects it will, but the states, many states reporting 30% to 50% cuts in their allegations of fooiz err's vaccine for next week. some messaging that that might just be a mix-up they were essentially given some old numbers for a training are protocol and now the real numbers are turning out to be less, but then there has been this back and forth between the administration and pfizer where there have been some suggestions, including from, you know, governor

meg, thank you so much, our meg tirrell. ty? >> as we mentioned, the fda is set to review moderna's vaccine later this week. for more on the vaccine pipeline, michael, it's always good to see you and great to have you here on this rather historic day. i guess first question is when all is said and done and all of the vaccines from moderna and j & j and astrazeneca get coming to us, is supply going to match ultimately demand in 2021? >> that's great questioning. good to be here with you, tyler. i guess one question is what do you think the demand will be? we actually did a survey and there's been a number of surveys out there suggesting that 50 to 70% of the american population wants to get one over the next year. if you do the math between moderna and pfizer, as well those coming with data in january, the numbers do clearly suggest there will be capacity to make that demand and that's why we're optimist being 20-21 will play out just fine. >> will there be capacity globally to meet demand? >> there will be capacity to meet globa

we appreciate it meg tirrell. with that vaccine around the corner either way, how will we distribute it once it hits the broader population grocery and drug stores think they will have a big role to play and joining me to discuss that is the evp of pharmacy and fuel operations at food city parent kvat foods. mickey, it's good to have you. first of all, are you targeting your involvement to be in these early weeks or once there's many more doses available to the broad population >> well, first of all, thank you for having me. we've literally prepared ourselves to be ready for whatever role we need to play. we're ready to go with the federal allocation when it rolls out, and we've also offered our services to the states should they deem that they need to count on us to help in that population as well. >> what advantages does a grocery store offer in this distribution process, because i've read, for example, you have wide and long store aisles where you can safely distance people as they wait and that kind thing, but

hi, meg. >> hi, scott well, this all-day meeting going on of outside advisers to the fda to discuss every facet of the data behind the vaccine from pfizer and biontech. you can see now pfizer's head of vaccines is answering questions from the fda committee and they plan to have a discussion and vote between 3 and 5. today. dr. steven hahn put out a statement trying to assure people of this process and the credibility of their review saying i can assure you no vaccine will be authorized for us in the united states until fda career officials feel confident in aof lllowing their families to receive it so speaking to knowing there is vaccine hesitancy, people are cautious about taking the vaccine. if the committee votes positively today, then it goes to the fda to decide whether to issue emergency use authorization. within 24 hours of that green light, the distribution of the vaccine starts simultaneously a cdc advisory committee will meet to give their recommendation to the biontech vaccine and we could be looking at the first vaccinations in. u.s. happening next week >> they could get that

now headlines on astrazeneca let's get to meg tirrell hey, meg. >> astrazeneca results that are coming out now are the data from two weeks ago, pooled efficacy of 70% for the astrazen emeca when, of course, it's 90% in one arm and 62% efficacy in the other arm. it's interesting to see that vaccine work its way through the regulatory process around the world as they're starting to submit to regulators here in the united states. folks from operation warp speed say those data are not sufficient for fda approval. of course, he's not the fda so we'll have to see what the fda does essentially the data we saw two weeks ago from oxford and astrazeneca. pfizer, we got a new set of data released ahead of a meeting of advisers on thursday this is the first time we're hearing the fda weigh in with their thoughts on those results. importantly on safety, the fda says that the results it saw suggest a favorable safety profile with no specific safety concerns identified that would preclude issuance of an emergency use authorization. side effects you may feel after you get your shots there are two, and

we're bound to see differences in all the states with this too. >> i would get one tomorrow, meg. obviously, if it were to come. i heard in your voice, a little bit of a snicker when you said essential employees. you couldn't even sell that, when you said media, for essential employees, i could hear it in your voice, like who made that up we are not worthy compared to -- >> i just know how eager you are to get your shot, and i mean, i don't know how old you are, i assume you're not over 75. >> anyway, my point was that's a stretch, essential workers my other question is, meg, you get the shot, you get the jab, what do you really think it takes before you get a couple of antibodies going you think within a week you have some limited immunity? i mean, you get that second booster obviously, but i just wonder two days, three days, four days, a week, two weeks, do you have any ideas or any evidence from the clinical trials at all for that >> we don't know exactly how long it takes. i mean, we do know that, you know, in the pfizer trial they did start counting the cases one week after t

meg oliver, thank you. tonight, we're hearing from healthcare workers and families with a warning: while we wait for the vaccine to be administered, this is not the time to let your guard down. cbs' janet shamlian has more. >> reporter: an unthinkable record: coronavirus deaths topping 3,000 for a second consecutive day. ( coughing ) tonight, california reporting the highest number of new cases ever. mississippi is completely out of i.c.u. beds. fort worth, texas, is doubling capacity at the morgue, and in new york city, indoor dining shuts down starting monday. >> the rate of transmission and the density and the crowding, that is a bad situation. >> reporter: the horrifying death toll includes names like stephanie smith, 29-years-old, about to be married. she should have been on her honeymoon the day she died. p people, and it'se've been trained to help people, and it's really hard right now to feel helpless. >> reporter: dr. shirlee xi says if only the doubters and nonmaskers could spend one day like she

meg tirrell on the pfizer vaccine development today. >>> we're going to watch the finalization of this stimulus package as the president last night posts a video on twitter blasting that relief bill, saying the direct payments don't go far enough, called it a disgrace he stopped short of saying he would veto it. take a listen. >> the bill they are now planning to send back to my desk is much different than anticipated. it really is a disgrace. i am asking congress to amend this bill and increase the ridiculously low $600 to $2,000 or $4,000 for a couple i'm also asking congress to immediately get rid of the wasteful and unnecessary items from this legislation. and to send me a suitable bill or else the next administration will have to deliver a covid relief package and maybe that administration will be me. >> in response to the comments, house democrats say they're going to try to work on a stand alone bill for those direct paymentsunder unanimous consent, but that's a high bar given that any single member can kill it. mike, as for the political ramifications, what does it say about th

meg tirrell now with the top story at the bottom of the hour. what did moderna say about its vaccines, specifically >> they called it a remarkable achievement, panel of expert advisers to the fda. led to both moderna and pfizer's vaccines getting to the public less than a year after the work began on them. the vote was 20-0 in favor with one abstention, that the scientific evidence for those 18 and older. there was discussion about potential for allergic reactions after a small number were seen following pfizer's growth. moderna noted that their ingredients aren't identical to those in pfizer's so it's not clear it will have that effect but it's something that the fda will pay attention to. if the regulator issues emergency use authorize ace, a panel will weigh in on that allergy issue over the weekend and next week almost 6 million doses are expected to go out across the u.s. along, of course, with 2 million doses of pfizer's shots shep >> some states are being told their allocations of pfizer's vaccine have been cut by 30 to 40%. is that true

the for more -- spike, you should say for more let's welcome in our own meg tirrell and meg i'll start off with you will more people get the moderna vaccine in this country or the pfizer vaccine in this country >> well, as of right now the supply deals that we've struck, the u.s. has bought 200 million doses of moderna's vaccines and 100 million dose of pfizer's vaccines we know they are working on a deal for an additional 100 million doe million dozes of the pfizer vaccine and we'll have to see how that shakes out. we should have equal availability of the vaccine and every single doze we hope gets used >> when we add 2,900 million, we get to 300 million but is that enough for 350 million people to be inoculated because it's a two-dose protocol? >> yes, exactly. you know, there are more vaccines that are being tested and developed, of course, from johnson & johnson, and we might get to see their data in january. that's a single-doze vaccine so that would mean more supply right off the bat. astrazeneca and novavax behind that the government do have options to order more from pfizer and

meg oliver, thank you. well, tonight "feed america" says there's a 60% increase over last year in requests for food assistance. and it's not just lower income americans who need help because the first round of stimulus checks were based on last year's tax returns. a middle-class family who lost a job this year is also feeling the impact. here's cbs' mark strassmann. >> reporter: worry kept jose cruz company on this morning drive. >> reporter: that's seven-month- old, valentina. >> reporter: her dad, a 52-year- old unemployed chef, picked up donated food, enough to stuff this van. it will feed families in crisis, including his. >> when i go to the bed, sometimes i cry myself. you know, i say, "god, help me, please." >> reporter: cruz fell hard and fast in march after losing his job. he made good money cooking at the mayflower hotel in washington, d.c.-- $92,000 last year. now, he volunteers full-time at "so what else," a food bank. the siege of this pandemic has eaten into america's middle class. >> what you

meg, thank you meg tirrell. >>> more vaccines coming we've got a possible treatment coming dan nathan, all good >> yeah. i think a way to play this when you think of the xlv that's the s&p health care select etf, some of the largest holdings are johnson & johnson, pfizer, merck, unh is here around 110. it had a base between 100 and 105. it looks like it's really poised to break out a lot of tailwinds a lot of companies are not going to be making profits that they could on some of these vaccines and treatments, but i suspect these are going to be around for a while here to me the xlv looks poised for a breakout it's only up 11% on the year that's probably a way to play it without idiosyncratic risk in any of these individual names. >> what if you want to do individual names, guy? moderna, pfizer, merck >> merck's its own category. in full disclosure, my wife works for merck. merck has underperformed recently how you play it, pfizer showed its hand the day the big announcement came out, the stock spiked up to 43. we talked about it, take the money and run and trade it down to 37. that's

cnbc's meg terrell covers science and medical for us what can we expect out of this meeting? >> reporter: shep, this is going to be a completely public meeting, a discussion of all of the safety and efficacy data we're going to hear from the fda about how it looks at the safety and efficacy we'll hear from the cdc how it plans to track all of the safety and efficacy once it gets on the market we'll also hear about experts about how to run the trials of the next vaccines if this one becomes available. pfizer scientists will present their data and then the committee discusses it all and votes. the fda doesn't have to follow the recommendations of the committee, but it usually does we got some clues in the briefing documents about how it's looking at the vaccine. on safety, the fda says there are no specific concerns that would preclude them from an emergency use authorization. it knows there are side effects from injection site reaction, fatigue and others people should be aware they may not feel great the day after the shot efficacy, it provides some efficacy after the first d