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Full text of "Salivation exploded, or, A practical essay on the venereal disease ... To which is subjoined, a dissertation on gleets and weaknesses ..."

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O R, A 



O N T H E 



Inefficacy of Salivation*, and recommend-* 
ing an approved Succedaneum. 


With fome remarkable Cases, which had withflood 
Three, Four, or Five Salivations, and were afterwards 
cured, by that fafe, eafy and certain Method, the 
Alterative One, of which a particular Account is 
given, and the Medicines ufed therein, 


A Dihertation on Gleets and Weakness, Seminal as 
well as Venereal, in both Sexes; with the Remedies 
belt adapted to each. 

Herein are defcribed, not only the molt eligible Medi¬ 
cines for the Cure of the Venereal Difeafe, but the 
moll powerful Ones to prevent it alfo. 

. * ¥? - y . ' 


’ ’ " ;-■» ** 

Opprime dum nova funt, fubiti mala femina morbi, 

nam mora dat vires. Ovid. 

- -—- - ——-—* 


Printed for S. BLADON, No. 13, ■ Pater-Noller Rowv 


[ Price Two Shillings. ] 



V ' • . •> ■ (i* *» . , ■ 

7\ jOtwitb(landing the number and variety of 
publications upon the prefent fubjsEt , 
Author flatters himfelf that his obflervations 
(the reflult of much experience) will not be un¬ 
acceptable to the Faculty; efpedally the junior 
part of it, to whofe perufal this Fflay is par- 
ticularly recommended\ 

Common cafes, or fuch as daily occur , and 
are not attended with any unufual fymptoms , 
are purpojely omitted j and to avoid prolixity, a 
few only of the other kind are inferted , they being 
f bought fujflcient to elucidate the fubjedl . 

Recent cafes are likewife pretermitted , in 
order to obviate the idea of relap fee, which 
even the mofl impartial reader might otherwife 
have fuggefted . 

Parliament Street , 

June 2. 6th, 1780. 







T HE Venereal Difeafe, beyond all others, 
having, by its peculiar virulence and 
frequent attacks upon the human body, made 
the moft alarming depredations therein, no 
temporal fubjeft I prefume ought fooner to 
claim our attention, than the thorough invefti- 
gation and fpeedy fubje£tion of fo formidable 
an enemy.—Many and various have been the 
opinions of the learned, relative to the time 
and place of its firft appearance—this cir- 
cumftance v h a $ afforded an ample field for 
deputation to both ancients and moderns; 
of whom fome the moft eminent, at different 
periods, have very ingenioufly and candidly 
treated upon the fubjedl: notwithftanding 
which, the matter is yet doubtful and 
likely to remain fo. A knowledge of the 
precife origin of the difeafe muft however 
appear of but little importance, when 
put in competition with that of the moft 
effectual remedy for the radical cure of 

B it. 

[ 2 ] 

it, I fhall therefore leave fuch contro- 
verfies to thofe who are fonder of, or may 
be better qualified to adjuft them than my- 
felf, and reft contented with recommending 
the molt rational and eafy method of remov¬ 
ing fo loathfome a difeafe. This mode of 
cure is the moil gentle and efficacious, as 
will appear in the following pages: it will 
ftand the teft of the ftridteft fcrutiny, being 
founded on the broad balls of long experience 
and uninterrupted fuccefs. In fupport of 
this affertion, I fhall produce fome very re¬ 
markable cafes, feledted from many hun¬ 
dreds, where the ufual or general modes of 

cure had proved abortive. 


It has been frequently obferved, that the 
knowledge of a difeafe is half its cure ; in 
no in fiance can I fuppofe this adage to have 
been more fully verified than in the Venereal 
Difeafe ; which, Proteus like, appears in fo 
many different forms, that very often it will 
require no final 1 ffiare of judgment and ex¬ 
perience to difiinguiffi it from fome other 
diftemper, whofe fymptoms it may referable 
in many refpefts, or with which it may in 




[ 3 1 

reality be combined. This being the cafe, 
we muft not wonder at the many errors 
daily committed by the ignorant, or inexpe¬ 
rienced in the profeffion. Almoft innume¬ 
rable have been the inftances of reputed rheu- 
matifms, nervous head-achs, wandering gouts, 
fcurvies, declines, confumptions, &c. &c. 
which, upon a minute inveftigation, have 
been proved to be venereal. A happy cir- 
cumftance, when this difcovery is made early 
enough to fave the patient from an untimely 
grave; but alas ! how frequently does the re- 
verfe happen ? This melancholy obfervation 
is particularly corroborated in the great num¬ 
ber of atrophies, or confumptions, by which 
the inhabitants of this ifland are many of 
them fuppofed to be deftroyed. This fata¬ 
lity has generally been afcribed to the cli¬ 
mate, but I am firmly perfuaded, that, upon 
a ftricl and impartial enquiry, many other 
caufes may be afligned 5 and amongft them, 
Venus will be found to have had no fmall 
fhare. I am induced to be of this opinion 
from the many inftances that have fallen un¬ 
der my own immediate infpedlion, where 
patients, after having been pronounced to be 

B 2 in 

in the laft ftages of a confumption, and given 
over as loft, have been perfectly reftored by 
the ufe of anti-venereals. A circumftance of 
fuch importance, moft certainly merits the 
attention of every medical pra&itioner. Should 
this admonition take the defired effedl, I {hall 
experience the greateft fatisfaftion in hav¬ 
ing rendered fuch an effential fervice to the 
community. In the following {beets it will 
evidently appear, that the Venereal Difeafe, 
in every ftate or ftage, from the mildeft to 
the moft inveterate, may be perfectly, eafily, 
and fafely cured, without falivation: and 
that the patient, although labouring under a 
confirmed pox, will not be confined within 
doors a {ingle day during the whole time he 
may be taking fuch medicines as will effeft 
a radical cure. I {hall likewife demonftrate 
that gleets of every denomination are curable, 
provided the origin of each be duly invefti- 
gated, and in confequence thereof, a fuitable 
remedy not only applied, but regularly per- 
fevered in for a length of time, proportion- 
able to the caufe : to the want of that perfe- 
verance, in my opinion, may often be af- 
cribed the want of fuccefs in the general 


[ 5 1 

treatment of gleets; for I do not recoiled 
(amongft the great number and variety of my 
patients for feveral years three cafes 
which did not give way, or were not cured, 
by properly and ftridly perfifting in the ufe 
of injections or bougies, and fome internal 
alteratives. To prove not only the inexpedi¬ 
ency, but the inefficacy of falivation in ve¬ 
nereal maladies, I fhall produce feveral cafes, 
in which its effeCts were merely palliative; 
in other words, afforded only a temporary 
relief, although repeated even to a fourth or 
fifth time; after which the fame patients 
(notwithftanding the violent fhock, and ma- 
nifeft injury their conftitutions had thereby 
fuftained) were perfectly and radically cured 
by that eafy gentle method, which I mean 
to recommend, namely, the alterative one. 
For argument fake only, .fuppofe we admit 
that falivation is efficient and might be de¬ 
pended upon; what man in his fenfes but 
would give the preference to the method here 
propofed ? When he confiders how extremely 
difgufting and painful the procefs of faliva¬ 
tion is univerfally allowed to be, the confe- 
quent confinement indifpenfably neceffary 


t 6 ] 

therein, and the many other disagreeables 
that generally or frequently fucceed it; fuch 
as destruction of teeth and gums, and the 
fcetid or flunking breath thereby occafioned ; 
the great relaxation of the falivary glands, 
or an erofion of their excretory duels, pro¬ 
ducing a copious troublefome flow of faliva, 
perhaps for the remainder of life; together 
with the derangement of the whole frame, 
in fuch a degree as feldom to be got the bet¬ 
ter of, even by thofe who may have been 
originally poflefied of the beSt Stamina, or 
Strongest constitutions. All thefe circum¬ 
stances duly confidered, it is rather furprif- 
ing that Salivation has not long Since been 
univerfally exploded ; the only affignable rea- 
fon mud be the want of a proper fucceda- 
neum; that, however, very happily for man¬ 
kind, can no longer be pleaded in excufe, as 
the alterative method is daily gaining ground, 
from the following very cogent reafons, viz. 
the operation of proper alteratives being fo 
extremely mild and gentle as to admit of 
being fafely administered at any time or fea- 
Son, to perfons of all ages, and of each fex: 
to pregnant women almoSt the whole time of 


[ 7 ] 

£edation, even to the lad month, from which 


happy circumdance, the foetus and its mo¬ 
ther both receive a cure at the fame time. 

Two other very material advantages are to 
be derived from the ufe of alteratives, fird, 
the certainty of cure, even in the word:, the 
mod: inveterate cafes, where many repeated 
falivations have proved ineffedtual; fecondly, 
not the lead: confinement being requifite 
throughout the whole courfe; which to the 
mercantile part of the world is a circum¬ 
dance of no little importance. The patient 
being able to tranfafl: bufinefs as well in the 
open air as elfewhere, and there being no 
other redridtion or alteration refpedting his 
diet, than the omifiion of acids, he will not 
be under any apprehenfion of a difcovery 
taking place in the family. Another parti¬ 
cular in favour of thefe medicines, is, that 
contrary to the effefts of mod: others, they 
will encreafe the appetite, and thereby acce¬ 
lerate the cure, during the performance of 
which, the patient’s food cannot be of too 
nutritious a nature, infomuch that meat mav 
be allowed twice or thrice per day, in pre- 



l 8 3 

ference to gruels, ptyfans, or flops of any 
* kind. The only difadvantage that attends 
the alterative method, is this ; patients being 
at large the whole time, and capable of 
purfuing either bufinefs or pleafure, fome 
are apt to prefer the latter, and very fre¬ 
quently not only negleit taking the medi¬ 
cine, but commit various exceffes, and fome- 
times contrail frefli infections, while we are 
endeavouring to remove the old one. Indeed 
fome have been frank enough to confefs, 
that a fpecies of ceconomy had given rife to 
thefe irregularities; from a fuppofltion that 
no additional expence would be incurred, 
they thought it therefore the properefl: time 
to gratify fuch inclinations : not confidering 
that violent exertions of the parts- affeited 
muft certainly procraftinate the cure, fhould 
they even be fortunate enough to efcape an 
increafe of the venereal virus. 

Salivation has none of thefe obfiacles 
to combat with: for when once a man has 
completely immerfed himfelf into that de¬ 
lightful ftate, it will feldom, if ever hap¬ 
pen, that he will, fo circumftanced, be pof- 
q feffed 

feffed of either ability or inclination to deviate 
from the moft rigid injunctions that may be 
impofed by his doctors, medicinal or divine. 
In fupport of this opinion, nothing more 
will be neceffary than a recital of feme few 
of the concomitant fymptoms or conftant 
attendants on a perfect falivation ; namely, a 
tumefaction of the head, face and throat, 
to a great degree, with much pain and in¬ 
flammation therein: the tongue frequently 
becomes too large for the mouth, which by 
this time is excoriated and extremely tender, 
together with the gums, tonfils, and all the 
neighbouring parts: in fine, the whole mouth 
and its appendages becomes one foul ulcer, 
from which iffues a flench that may be better 
conceived than defcribed, accompanied with 
a ptyalifm or fpitting, in quantity from two 
to fix pints in the twenty-four hours; which 
agreeable procefs is to be continued feme 
weeks, and in the courfe of a few months, 
perhaps, repeated again and again. The fame 
advantage as the foregoing, has the old me¬ 
thod of curing claps by mercurials and draf- 
tic purges, which were generally repeated 
every two or three days for a considerable 

C length 

[ *° 1 

length of time, till the difcharge put on a 
more benign afped; or the patience, or 
ftrength of the patient being exhaufted, oc- 
cafioned a difcontinuance thereof. From 
thefe premifes we muft readily infer, that a 
perfon thus constantly harafled by Strong, 
rough medicines, could have little relifh or 
inclination to tranfgrefs the laws of fobriety. 
Confideratis conpderandis , every impartial man 
moft certainly will prefer the alterative mode 
of cure, to that by falivation. 

Having premifed thus much, now let us 

turn our thoughts to the moft eligible means 

of obtaining a radical cure for this prevalent 

difeafe; it having often with great truth been 

obferved, that as nothing can be done with 

greater facility, than to cavil or find fault, 

therefore no merit will be derived from fuch 

a procedure, unlefs at the fame time it fhall 

be accompanied with fome plan or fcheme 

more likely to effed the purpofe in queftion. 

To obviate this reffedion, I (hall not only 

propofe fuch a remedy as will be moft likely 

to anfwer, but fhall alfo produce, in fupport 

of it, fome cafes which (from the peculiar 

* > 


r » ] 

fuccefs attending them) will go near to call 
in queftion the veracity of the man who re¬ 
cords them: be that as it may, fuch an idea 
fhall not prevent my giving a faithful rela¬ 
tion of them. Before however we enter 
upon that part of the bufmefs, I fhall make 
fome obfervations on the means by which 
thofe events took place. Very numerous and 
different are the prefcriptions which at va¬ 
rious periods have been recommended, as 
fully competent to fubdue the venereal poi- 
fon ; amongft the great variety offered for 
this falutary purpofe, many were diametri¬ 
cally oppoiite to each other, advocates how¬ 
ever were not wanting to extol their mani¬ 
fold virtues: on thefe occafions, both the 
vegetable and mineral kingdoms were tho¬ 
roughly ranfacked and attentively examined, 
and many of their properties afcertained by a 
feries of ingenious experiments: and even at 
the prefent period, we are fometimes under 
the neceffity of having recourfe to both, in 
the reduction of fo powerful an opponent as 
the venereal difeafe. Be it remembered how¬ 
ever, that vegetables alone, when properly 
prepared, will effect a cure in many cafes, 

C 2 although 


[ I- ] 

although in others it muft be acknowledged 
that minerals will likewife be required. The 
gums will fome of them be found of fmgular 
ufe, particularly camphor, in every ftage of 
the difeafe, from a gonorrhoea to a confirmed 
lues; in the former it will greatly contri¬ 
bute to alleviate the heat of urine, as well 
as corredt the virulence; and in the latter it 
ought never to be omitted, for feveral rea- 
fons 3 in the firft place, it is a moft power¬ 
ful alterative ; in the next, it ftrengthens the 
nerves, exhilarates the fpirits, and when 
joined with minerals, fortifies the ftomach 
and bowels againft any of their difagreeable 
or pernicious effedts. It diffufes a general 
warmth throughout the body, and greatly 
affifts in conducing other medicines towards 
the cuticular and renal glands. As to the 
choice of alterative medicines heft adapted to 
the cure of the venereal difeafe, I believe 
none will be found more efficacious than a 
compofition of the following, viz. camphor, 
antimony and fulphur: in fome cafes it may 
be neceffary to add both mercury and opium. 
Thefe muft be affifted with decodtions of the 
3 . woods 

[ >3 1 

woods* in quantities fufficient to attenuate 
and faturate the whole mafs of contaminated 
juices. Any particular recipe or prefcription 
of the above, would be of very little ufe, 
as not only .the dofes, but the quantity of 
each ingredient mu ft fo frequently be either 
in created or diminifhed agreeable to the vari¬ 
ation of fymptoms and circumftances; which 
fometimes require even the omiffion of one 
or more of thofe ingredients. The age, fex, 
temperament or conftitution of the patient, 
as well as the degree of infection, muft render 
it indifpenfably neceffary to make the alte¬ 
rations above mentioned. Another material 
circumftance frequently occurs, namely, the 
addition of other acrimonious humours ; to 
which, particular attention muft be paid, or 
we fhall not fucceed in our endeavours to 
remove the venereal one. From hence it 
muft evidently appear, that no particular re¬ 
cipe can be invariably relied upon, in this or 
any other difeafe. 

* Guaiacum, farfaparilla, china, faffafras, Tantalum 
glycyrrhiza, &c. 


f r 4 ] 

The fymptoms of a virulent gonorrhoea 
(commonly termed a clap) are too well 
known to require any defcription in this 
place: let us therefore confider upon the 
means moil: eligible for its removal. The 
cure may be eafily and fpeedily effedted, if 
undertaken when the firft fymptoms are per¬ 
ceived; particularly that gentle irritation, or 
trickling fenfation in the urinary paflage, 
which fo frequently precedes the difcharge : 
the difeafe, when taken at this ftage, may be 
very fafely removed in the fpace of two days, 
by applying medicine immediately to the 
part affected; this cannot be conveniently 
done in any other form than that of an in- 
iection, which (hoiild be compofed of fome 
gentle detergent that will ftop the further 
progrefs of the venereal virus, by preventing 
its abforption. Chancres may likewife be 
almoft as fpeedily removed, provided the re¬ 
medy be applied at their very firft appear¬ 
ance. ~ 

Should this precaution be omitted, the 
acrid matter will corrode the parts, and pro¬ 
duce ulcerations ; confequently a longer time 


I J 5 ] 

will be required to effect a cure; and it may 
be neceflary to adminifter internals to pre¬ 
vent a flow of humours to the part which 
might retard the cure, if xot entirely frus¬ 
trate our intentions. 

If the complaint be not removed in the 
early ftages, it will foon become confirmed; 
and then due regard muft be paid to the pa¬ 
tient's habit of body, mode of living, &c. 

It is with me a matter of furprife, that 
injections have not been in more general 
practice ; as nothing certainly can be more 
rational, than to apply the remedy to the part 
affected. The advantages or the reverfe, at- . 
tending the ufe of them, muft evidently 
arife from the ingredients of which they are 
compofed : no man fure can be fo prejudiced 
as to declare that his objection is merely to 
that particular mode of conveying a medi¬ 
cine: to fpeak impartially; if crude, cor- 
rofive, indigefted ulcers in every other part 
of the body require topical applications, 
why, in the name of common fenfe, fhould 
they be neglefled or omitted in parts natu¬ 

t 16 ] 

tally fo very delicate and fenfible, as the or¬ 
gans of generation are inconteftably allowed 
to be? negleCts of this kind are frequently 
produ&ive of the moft difagreeable confe- 
quences ; they may, independent of the 
injuries from abforption, give rife to gleets 
and obftruffions in the urethra, which if not 
attended to, may terminate fatally. The ftil- 
licidium, or running, is very uncertain as to 
the time of its appearance ; fometimes it will 
happen in fix hours after the embrace, at 
others, twice as many weeks have elapfed 
before it has been perceived; thefe, I muffc 
acknowledge, are not very common cafes, but 
fuch as have really fallen under my infpec- 
tion, as will be feen in the fequel: in general 
however, it appears in lefs than ten days. 
Chancres likewife vary as much in this parti¬ 
cular. In the treatment of a confirmed clap, 
a great deal will depend upon its being fimple 
or compound; in other words, whether it 
originated from a perfon who had only a go¬ 
norrhoea, or who at the fame time was 
poxed likewife. In the latter cafe, power¬ 
ful internals will be abfolutely neceffary ; in 
the former, a cure may frequently be accom- 

[ if ] 

plifhed by inj.e&ion only. Claps and Chancres 
are often contra&ed at the fame time, but 
do not always make their firfl: appearance 
together $ I have feen inftances even where 
fome weeks have intervened. 

As the compofition of inje&ion, like that 
of every other remedy, muft vary according 
to circumftances, I fhall decline giving any 
particular recipe; one general ingredient how¬ 
ever I will venture to recommend, namely, 
Armenian bole, which from its abforbent 
and other good qualities will prove highly 
beneficial both in correfting the venereal acri- 
• mony, and defending the found parts of the 
urethra therefrom. 

In the cure of claps, fome practitioners 
have attended too much to the colour of the 
difcharge, others to the eonfiftence of it y 
both are fallacious, particularly the former ; 
as it will fometimes be of a deep yellow, even 
to the laffc day, efpecially in bilious habits: 
frequently it is equally high coloured in old 
gleets of feven or ten years ftanding, where 
the party has been entirely free from infec- 

D tlon 

r »8 ] 

tion all that time, as in fome cafes has beerf 
fufficiently manifefted by the healthy ftate of 
wives and children. A difcharge of fimilar 
colour and confidence is often to be found 
attending the flu or albu-s, as it is called. 
From hence will follow the indifpenfable 
necefiity of examining further, than juft the 
ftate of the running: the beft criterion will 
be the afpedt of the urethral orifice, and the 
fenfations throughout that tube. 

Many families have been rendered un¬ 
happy from the length of time this difeafe 
fometimes requires to make its firft appear¬ 
ance : for a man, after performing a kind of . 
quarantine of three weeks or a month, and 
' no fymptom of infection having fhewn it- 
felf during that time, would naturally con¬ 
clude himfelf entirely free from it, and pro¬ 
ceed accordingly; but how great his afto- 
nifhment, as well as chagrin, to difcover 
(perhaps a month or two afterwards) the moft 
indifputable figns of his being infected: fe- 
veral inftances of this kind have fallen under 
my infpedtion, fome of which, I muft con- 
fefs, I fliould not have credited, had not 



C *9 ] 

•■o' u 

they been accompanied with proofs not to be 
contefted. From this we may infer, that 
although the virus very often makes the mod 
rapid progrefs, at other times its operations 
are as fluggifh: this may arife from the de¬ 
gree of infection, or the patient’s habit of 
body, or from both. 


A merchant in the citv of London, four 
years fince, applied to me in confequence of 
great heat in making urine, painful erections, 
and a difcharge of matter from the urethra, 
fo acrid, as to threaten a phymofis, it having 
already excoriated the greateft part of the glans 
penis. Thus fituated, he defired to know if 
I did not call his diforder a clap; to which 
I replied in the affirmative, and that it was 
not of the mildefl kind : “ Then fir, faid he, I 
fhall mention a circumftance, that I think 
will furprize you, which is, that not a fingle 
iymptom of the difeafe appeared until two 
months and three days after it was contracted 
upon this account he deemed it not venereal, 
1 aflured him however that it was fo, and 

D 2 could 

C 20 ] 

could be removed only by treating It as fuch. 
My patient was not of a bad habit of body, 
nor had his blood been previoufly heated by 
intemperance, the chordee was notwithftand- 
ing fo troublefome, that I expected to have 
been obliged to ufe opiates, which I am very 
feldom under the neceflity of doing; injec¬ 
tions generally anfwering the purpofe, by 
fpeedily removing the inflammation and its 
confequences : my only obje&ion to opium in 
thefe cafes, is, the conftipation which moftly 
attends the ufe of it; although I am not an 
advocate for the old method by cathartics, 
yet I would not be underftood to recommend 
abfolutely the reverfe; which muft indubi¬ 
tably tend to encreafe, rather than alleviate 
fymptoms ariflng from inflammation. It 
will be found fully fufficient, that the intef- 
tinal evacuations be the fame as at the time 
of perfect health.-—Now to return to my pa¬ 
tient ; he was much alarmed at the high de¬ 
gree of pain and inflammation, which how¬ 
ever was confiderably lefiened in the Ipace of 
two days, by means of injection and internal 
alteratives ; three weeks continuance of which 
perfectly cured him, without any confinement 


E 2i ] 

At \ % Jyl , > 

pr alteration in his ufual mode of living, e%*> 
pept abftinence from acids and fpirituous U-? 


A gentleman of Borfetfhire, in the 
month of February, 177B, came to town on 
purpofe to be under my care; his fymptoms 
at that time were a difcharge of yellow mat¬ 
ter from the urethra, chancres on the glans 
penis, a large bubo im the left groin, and a 
fmaller one in the right. Upon my enquir¬ 
ing into particulars, he folemnly declared 
that he had not the leaf!: reafon to think him- 
felf infected, till upwards of nine weeks after 
coition, when he was attacked with a trick¬ 
ling fenfation in the urethra, which was fol¬ 
lowed by a running and heat of urine ; chan¬ 
cres foon afterwards appeared, and were fuc- 
ceeded in a fhort time by tumefaction of the 
inguinal glands, which thereupon became 
extremely painful. He was at firft attended 
by a furgeon in his own neighbourhood, who 

bled him very freely, gave ftrong mercurial 


purges repeatedly, and ordered him to dilute 
plentifully with barley water, &c. Fomen- 

** \ w 


tations and cataplafms were applied to the 
buboes till fuppuration took place, when he 
propofed to difcharge their contents by means 
of cauftic or infcifion, but the patient not 
confenting to either, immediately left the 
country, and loon after applied to me, re¬ 
queuing that I would remove them without 
opening or differing them to break, as he had 
the greateft averfipn to fores of every kind, 
and much dreaded all chirurgical operations : 
I told him, that considering the very forward 
ftate in which the buboes at that time were, 
(the fluctuation of matter being readily felt 
upon the flighted: preffure) I could make no 
other promife, than to exert my bed abilities 
in endeavouring to effect what he fo ardently 
defired; obferving Hkewife, that I frequently 
had been fortunate enough to render thole pain¬ 
ful operations unneceflary by the ufe of inter¬ 
nal medicines alone; which, in my opinion, are 
the only ones that can fafeiy be relied upon. 

As to the repelling of buboes (in the vul¬ 
gar phrafe, putting them back) I never make 
the lead hefitation of attempting to effedi it, 
for this obvious rcafon, that a bubo is not 

a critical 

a critical abfcefs, of which I am well con¬ 
vinced from daily experience, notwithftand- 
ing the general received opinion to the con¬ 
trary : I have feen many instances where 
buboes have been carefully brought forward 
to the tlioft perfedt Suppuration, liberally 
opened, and a copious diicha.rge very induf- 
trioufly encouraged for the Space of four, five, 
or fix months ; notwithstanding which the 
parties have remained completely poxed ; as 
the nocturnal pains, foul ulcers, and erup¬ 
tions fufficiently manifefted a few months 
afterwards, when they became my patients, 
and were radically cured by the alterative me¬ 
thod in half that time. This being a fact 
not to be controverted, why Should fuppura- 
tion be encouraged, as it muft be attended 
with great pain, filthinefs and inconvenience ? 
And after all, not being critical, a regular 
courfe of medicines will be indifpenfably 
necefiary: the cicatrix or fear is likewife a 
circumftance not the moSt agreeable, efpeci- 
ally to the fair fex.—Without apologizing for 
this digreffion, I will haflen to my Dorfet- 
fhire friend. Entertaining thefe fentiments, 

I immediately fat about the difeuffion of his 


% - buboes ; 

*■? «w 

[ 2 4 ] 

Buboes; for which purpofe alteratives were 

\ . * 

adminiftered internally, and detergent injec¬ 
tions and dreffings applied to the urethra and 
the chancres on the penis: by thefe means 
the fymptoms gradually abated, arid at the 
end of a month he thought himfelf cured; 

but I adVifed a continuance of the medicines 


three or four weeks longer, on account of the 
high degree of virulence we had had to en¬ 

counter with: he readily confented to per- 
fevere in the ufe of them, having already ex¬ 
perienced fuch falutary effects; and to fhew 
that he did not think the decodtion at all 
naufeous, he generally drank it at meals 
in lieu of any other liquor. Thus, in lefs 
than two months, without being confined to 
the houfe a fingle day during the whole courfe, 
he was perfectly re-eftablifhed in health, and 
has remained well ever fince. He was highly 
pleafed at the removal of the buboes without 
opening, and very generoufly rewarded my 



[ 3 

C A S -E III. 

. In the month of July, 1777, a gentleman 
requefted my advice upon the following fymp- 
toms; an unufual (though not painful^ fen- 
fation in the urethra, a difcharge therefrom 
very fmall in quantity, and of colour fo 
light as fcarce to tinge his linen. I was of 
opinion that thefe fymptoms were the harbin¬ 
gers or forerunners of a clap j but he ilrongly 
infilled that his diforder could be nothing 
• more than weakriefs, or a iirain, as he had 
had no venereal connection for eleven weeks 
previous to this indifpofition. 1 informed 
him, that fhould the cure of his difeafe be 
undertaken in this early ftage, I believed it 
might be removed in lefs than a week, if he 
would ftri&ly adhere to my inftruCtions, but 
as he feemed fo firmly perfuaded that his 
diforder was not infectious, I adviled him to 
wait only a fliort time, and he would then be 
perfectly fenfible of the real nature and ten¬ 
dency of it. Three days only had elapfed, 
before he paid me a fecond vifit, when I 
found my prognoftick fufficiently verified; the 
urethia and glans nenis beincr highly inflamed, 

E great 

L 26 ] 

great heat in making water, fome pain in 
erection, and a difeharge of yellow matter 
ifluing from the urinary canal; he was by this 
time fully convinced of his error, and re- 
quefted that I would relieve him as expedi- 
tioufly as poffible.—I told him that his delay 
of three days would procraftinate the cure 
more than a week, and in the prefent ftate 
of the difeafe I judged that it would at lead: 
require a fortnight, fhould even his tempe¬ 
rance and regularity not be called in queftion. 
However, by the ufe of injection and a few 
alterative pills, he was perfedlly cured in 
thirteen days. 


A gentleman in Weftminfter fent for 
me two years fince, to give an opinion upon 
a ftillicidium, or difeharge from the urethra, 
which had firft made its appearance two days 
before I faw him ; he was quite at a lofs to 
account for it, not having copulated for up¬ 
wards of two months prior to that period. I 
enquired whether he felt any irritation or 
trickling in the urinary pall age, he anfwered 


[ 2 7 1 

in the affirmative, upon which I pronounced 
the cafe to be venereal, although the run¬ 
ning was perfectly clear, and the parts en¬ 
tirely free from any external inflammation. 
My patient, however, feemed to think that I 
had formed an erroneous opinion; 1 there¬ 
fore defired him to defer uflng medicine of 
any kind for a day or two, in which time I 
made no doubt of an alteration in his fenti- 
ments. The next morning I was again fent 
for, and informed, that the parts did not 

. - • ' • • • • • . . .i. i... ., 

look quite fo cool as on the preceding day, 
and that his urine felt rather warmer than 

i \ 

ufual, thefe fymptoms he attributed to fome 
things he had ate and drank the day before, 
I replied, that in twenty-four hours 1 was 
fully perfuaded he would affign another caufe. 
Before breakfaft the next day, he fent for me 
again, and faid that he no longer entertained 
the leaft doubt of the difeafe being infec¬ 
tious, having lately perceived fome fymptoms 
of an approaching chordee 5 the running wa$ J 
now become yellow, the parts were inflamed 
externally as well as wdthin, and he could 
not make urine without fome degree of pain. 
I prepared for him a cooling injection, of 

E 2 which 



[ *3 ] 

which he ufed a fyringeful night and morning, 
and as he was very fubjed to the gout, I ad- 
miniftered no other medicines internally, than 
decodions of the woods and camphor, by 
which means, in the fpace of feventeen days, 
the cure was very ealily completed. 

» a a • »* ^ *. ■- • *. 

* CASE V. 

A gentleman in the county of Kent, put 
himlelf under my care on the ninth day of 
December, 1779; he had enjoyed a very good 
ftate of health for fome years, till within 
three days of his ^application to me, when he 
difcovered a yellow running from the urethra, 
attended with a heat of urine, and an inflam¬ 
mation of the glans penis and praeputium. 
There was likewife a fmall chancre on the 
fraenum. After ocular demonftration, I af- 
fured him that his difeafe was venereal, my 
patient was not of a different opinion (having 
been frequently infeded before) but he ex- 
prefied great aftonifhment at its being fo; from 
the circumftance of not having had any vene¬ 
real intercourfe fince the fifth day of the preced¬ 
ing September, and having been entirely free 


[ 2 9 ] 

of every fymptom of the difeafe till the fixth 
day of December; an interval of thirteen 
weeks and upwards from the time of con¬ 
tracting the difeafe, to that of its appearance. 
Upon my interrogating him very clofely as 
to the commencement of this affair, his an- 


fwer was, that he could have no intereft in 
deceiving me, and that it was impoffible he 
fhould be miftaken, having a memorandum 
in his pocket-book of fome particular occur¬ 
rences of that day, relative to this bufnefs, 
which with him reduced the matter to an ab- 
folute certainty. I obferved, that probably 
fometime fubfequent to that period he might 
have been too free in his libations to Bacchus, 
and be thereby deprived of recollecting his 
laft engagement with Venus. This fuppofi- 
tion he obviated, by declaring upon his honour 
that he had not been inebriated for feveral 
months paft, on the contrary. Ire had rather 
lived abitemioufly than otherwife. This 
gentleman’s health was perfectly re-eftablilhed 
in three weeks, by the ufe of internal alte¬ 
rants and external detergents. The foregoing 
cafes having beeixielcCUd from many fimiJar 

O J 

ones, to drew what great length of time the 


L 3 ° 3 

venereal difeafe fometimes requires to mani- 
fell itfelf let us now advert to others diame¬ 
trically the reverfe in point of time. 


A merchant in the city, who feveral 
years ago had been my patient, confulted me 
in January laft; he complained of an irrita¬ 
tion in the urethra, and fome heat in the 
glans penis, which appeared rather inflamed 
externally. He informed me, that his laft 
connexion had been only on the preceding 
evening, at about eleven o’clock, and antece¬ 
dent to that, he had not committed an act of 
venery for more than five months, during which 
time his health had been remarkably good. 
At fix o’clock that morning he was awakened 
by a (harp pain in the yard, which loon abated, 
but did not entirely go off, a difagreeable 
heat and irritation ftill remaining. From the 
lymptoms coming on fo early as within feven 
hours after the embrace, he could not believe 
his complaint to be venereal, but fuppofed 
that it arofe from friction, and the bad wine 
he had that night drank; I therefore declined 


C 3 1 1 

4 « 

to prefcribe any medicines, but advifed that 

he fhould live after his ufual manner, and 
• 4 

think no more of the difeafe till it might 

become more worthy of his attention ; which 

* * 

happened two nights afterward, by the pain 
he experienced from a chordee; there was 
likewife a yellow running from the urethra, 
accompanied with a heat of urine; his doubts 
by this time being perfectly removed, he im¬ 
mediately entered upon the ufe of injection 
and pills, by which he obtained a cure in 
lefs than three weeks. 


A naval officer in the month of March, 
J 77 8 ’ was attacked with an unufual warmth 
in the urinary paffage, in lefs than fix hours 
after coition, and it gradually encreafed for 
three days, when a copious running came on, 
attended with a fmarting of urine: in this 
ftage of the difeafe, he placed himfelf under 
my care, informing me that he was lately 
returned from a long voyage, and for feveral 
months pad: had not had an opportunity cf 
getting the infection, he could therefore 


[ 3 2 ] 

be very certain as to the date of his dis¬ 
order, having been entirely free from vene¬ 
real complaints for two years before. In 
effecting this gentleman’s cure, near a month 
was required, by reafon of the high degree of 
fcurvy with which he was at that time in¬ 
fected.] ' . 



- • ' „ r 

A gentleman in the county of EflTex, 
about fix months fince, paid me a vifit on the 
following account; having taken a night’s 
lodging with a lady of his acquaintance, the 
very next morning at breakfaft he felt fome 
uneafinefs in the urethra, which in the courfe 
of a few hours encreafed, and at the end of 
five days terminated in the fymptoms of 
both clap and pox, viz. a difcharge of viru¬ 
lent matter from the urethra, with heat of 
urine, &c. and three chancres externally; 
two on the prasputium, and one on the glans 
penis. He was not much furprifed at the 
early appearance of the difeafe, as with him 
it generally happened fo ; he neglected how¬ 
ever to life medicine of any kind, till it had 


arrived at the ftare above-mentioned, when, 

7 - he 

[ 33 1 

he became my patient ; and without further 
delay began upon a courfe of alteratives and 
detergents, which effe&ed his cure in lefs 
than a month* 

To the peculiarities of confutation, as - 
well as degrees of infeftion, muft be attri¬ 
buted the different periods in which parti¬ 
cular difeafes make their appearance. This 
circumftance may depend on the difpropor- 
tion of one or more of the ingredients or 
materials which compofe the human body. 
Some men are naturally fo irritable and in¬ 
flammable both in body and mind, as inftantly 
to take fire like tinder or touchwood, from 
the fmalleft fpark ; while others of cold 
phlegmatic habits, are (as is to be expedled) 
quite the reverfe. 


- a ' 1 r v ‘ + 

Four years fince, a gentleman in the 
county of Northampton, made a journey to 
town, to confult me upon what he called a 
weaknefs of a particular kind, as it was ac¬ 
companied with great inflammation; I im- 

F mediately 

[ 34 I 

mediately fufpected what the cafe was, and 
upon examination, found it to be a moft 
virulent clap, with an incipient phymofis ; 
he complained likewife of a chcrdee. I was 
much furprifed when he told me that his 
apothecary had not deemed it veriereal, but 
treated it as arifing merely from relaxation, 
giving large dofes of Peruvian bark and elixir 
of vitriol. My patient faid that the only 
reafon why his diforder had not been judged 
infectious was, that it did not discover it- 
felf till more than fix weeks after coition ; 
from which circumftance the apothecary had 
declared, that it could not poffibly be vene¬ 
real. By the ufe of deterfive injections and 
alterative pills, he returned home in perfect 
health at the expiration of about three weeks, 



In the month of December, 1778, a 
tradefman in Weftminfter commenced my 
patient, in confequence of a virulent gonor¬ 
rhoea which he had contracted more than a 
month before his application to me, and of 
which he gave the following account; that 



[ 35 ] 

- . >, V. '' 'N 

in fix hours after copulation, he perceived an 
unufual fenfation in the yard, a kind of trick¬ 
ling or itching in the urinary canal, which 
for upwards of three weeks had been a little 
troublefome, but by no means painful, until 
the 26th day, when a clear colourlefs dif- 
charge iflued from the urethra, which now 
began to be much inflamed, and felt very 
fore whenever the urine pafied through it; 
on the 28th day, the running was quite yel¬ 
low and rather copious; and upon the twen¬ 
ty-ninth he was attacked with a chordee, 
which induced him to be under my care the 
next morning 3 he faid he fhould certainly 
have applied fooner, but the inconvenience 
he experienced previous to the 26th day was 
fo trifling, that he had not entertained the 
leaft idea of his complaint being venereal; * it 
was however entirely removed in fifteen days, 
by the fame means as were ufed in fome of 
the preceding cafes. 

F 2 


r • [ 36 ] • 


A gentleman in the county of Surry 
fent for me in the month of Auguft, 1778, 

I found him labouring under a confirmed 
pox, of which the following were his fymp- 
toms, a violent head-ach, nocturnal pains 
\n the fhin bones, with nodes thereon, a large 
foul ulcer in his throat, upon the left tonfil, 
a heat in the urethra, and an obftrution 
therein : upon my requefting to know every 
particular relative to the rife and progrefs of 
the difeafe ; he informed me, that it was 
contracted about ten months before, and one 
thing appeared very ftrange to him, namely, 
liis knowing himfelf to be infected in lefs than 
twelve hours after the connection, from a very 
troublefome irritation in the urinary paflage, 
'which feized him about that time, and for 
fome days encreafed notwithftanding his im¬ 
mediate application to a furgeon, who ordered 
almond emulfions with nitre, manna and falts; 
and to dilute freely with barley water, in 
which gum arabic had been diffolved, partial 
warm baths and venefetion were not omitted; 
|n the courfe of a week or ten days, mercu¬ 

t 37 ] 

rial ointment was ufed very liberally for at 
lead a month, with brifk purges at intervals. 
The running, he faid, was very plentiful for 
the fpace of five or fix weeks; he then too 
balfamics for three weeks, and was thought 
to be cured; however, in about feven o r 
eight weeks afterwards, he perceived his 
health to be gradually on the decline, a dimi¬ 
nution of appetite, ftrength and fpirits, and 
deep interrupted by wandering pains in his 
head and limbs:—nodes loon after formed on 
the fhins and an ulcer in the throat. On the 
appearance of thefe fymptoms, another fur~ 
geon was employed, who adminiflered large 
quantities of the fublimate folution for a 
confiderable time, when finding that the dif- 
eafe did not give way, he put himfelf under 
my care, and was perfectly cured in two 
months, by the alteratives recommended in 
the 12th page, and a few bougies to remove 

* V \ 

the urethral obftrudlions. 

. Be it obferved, that no injections had been 
ufed in this gentleman’s cafe ; to which cir- 
cumftance, in my opinion, may be attributed 
the want of fuccefs, for had a proper deter- 


I 33 ] 

gent one been applied in the beginning, the 
venereal matter would not have been ab- 
forbed, and confequently the pox with its 
difagreeable attendants been thereby pre¬ 

. . 1 ' 1 ' 

. * » 



A gentleman in Wellminfler, eighteen 
months lince, eonfulted me in confequence 
of a boil (as lie termed it) feated among!! the 
hair on the pubes very near the penis. This 
ulcer had refilled every application his furgeon 
had made to it for three or four weeks. From 
the hard edges and other appearances, I pro¬ 
nounced it to be a chancre; this my patient 
did not at that time credit, however, not long 
after he altered his opinion upon the appear¬ 
ance of a bubo in the left groin, which in a 
few days became very painful, when he paid 
me a fecond vilit, and requelled to have it 
repelled: that was performed, and a cure 
effefted by an alterative courfe in about thirty 


[ 39 } 


In the month of November, 1778, a gen¬ 
tleman in the county of Middlefex labouring 
under a confirmed lues venerea, applied to 
me for its cure; the fymptoms at that time 
were, a finall node on the right fhin bone, an 
ulcer in the nofe, nodurnal pains, and a cop¬ 
per coloured eruption overfpreading a great 
part of his body. He informed me, that, 
till within the laft twelve months, he had 
never experienced a fingle fymptom of the 
venereal difeafe, and that hisprefent affiidions, 
if they were venereal, muft arife from a clap 
contracted a year before, which denoted a 
high degree of malignity, the inflammation 
being very confiderable and of long duration, 
attended with heat of urine, chordee, &c. tlie 
running he faid was copious, and continued 
upwards of five weeks, in which time he had 
been purged every three or four days, had 
rubbed in a large quantity of mercurial oint¬ 
ment, and afterwards taken eledaries and 
pills in abundance: in confequence of this 
procefs the fymptoms had difappeared, and at 
7 the 


C ' 4° ] 

the end of two months his cure was pro¬ 
nounced. Some few months after* however, 
he perceived his health to be gradually on the 
decline, without being able to affign the real 
caufe, not having the lead: fufpicion of vene¬ 
real matter ; his appetite and ftrengtH daily 
decreafed, his fleeps were fhort, interrupted, 
and afforded little or no refrefhment, and at 
length colliquative fweats enfued: thus cir- 
cumftanced, he confulted a phyfician, who, 
judging his cafe to be a confumption, put him 
under a courfe of afs’s milk, &c. &c. for & 
confiderable time, but growing every day 
worfe and worfe, he was ordered a change of 
air, and removed into another county. Find¬ 
ing however no greater relief from the alte¬ 
ration of air, than he had before experienced 
from medicine ; he began to defpair, and moll 
earneftly wilhed for his diffolution. Fortu¬ 
nately, an old acquaintance from town called 
to fee him, and upon hearing fome of his 
fymptoms llrongly urged him to become my \ 
patient, he accordingly did fo, and was per¬ 
fectly cured in the fpace of three months, 
merely by the ufe of alteratives. 


t 41 1 


A girl on the town applied to me upon the 
tenth of November, 1778, and faid fhe fup- 
pofed it would be neceflary for her to undergo 
a thorough repair, not having been free from 
infe&ion for a confiderable time y her fymp- 
toms then were, an ulcer in the throat, a 
foul eruption on the abdomen, a brace of 
fmall buboes, and a great difcharge of acrid 
matter from the pudendum. As fhe was ex¬ 
tremely anxious to have the buboes difperfed, 
I told her that no time fhould be loft, and 
confequently advifed the immediate ufe of 
medicine - y fhe replied that it muft be deferred 
till next day, as her miftrefs expefted much 
company that evening, and had engaged her 
to one gentleman in particular, with whom 
fhe was to deep that night, his name having 
been entered in the book for that purpofe 
fome days fince y and for which he had paid 
the ufual retaining fee.—I was not furprifed 
at this account, fimilar ones having occurred 
before, and particularly this inftance y a friend 
of mine, an officer in the army, made appli¬ 
cation to a lady Abbefs to know on what 

G night 


[ 4 2 } 

night a particular nymph would be difen- 
gaged ; after infpedting her ledger, fhe in¬ 
formed him that the lady was difpofed of for 
twenty-two nights, and if he pleafed the 
would take down his name for the twenty- 
third, upon paying the ufual compliment.— 
But to return to my patient; fhe called upon 
me again the next day, and without any fur¬ 
ther delay entered upon a courfe of alteratives, 
by means of which her health was perfectly 
re-eftablifhed in lefs than feven weeks. She 
was under great apprehenfions left the bu¬ 
boes fhould fuppurate and occafion fears, but 
was foon made eafy on that head, as they 
difperfed very kindly in a few days, the other 
iymptonis gradually difappeared, and in little 
more than three weeks fhe thought herfelf 
well, it was therefore with fome difficulty 
that (he could be perfuaded to continue the 
medicines a fhort time longer, in order to 
confirm the cure. 

c a s e xv. ; : 

A mechanic in Weftminfter, being em¬ 
ployed in the haufe of a nobleman, became 



, f 43 ] 

acquainted with the lady’s woman, and after 
many entreaties, perfuaded her to grant him the 
lad favour; in the fpace of a fortnight however, 
he was fully convinced of the impropriety 
of the connection, being at that time obliged 
to commence my patient, on account of a 
large chancre feated on the anterior part of 
the fcrotum; it was the mod malign that 
ever came under my infpedion, being in 
dze equal to a drilling, and had the appear¬ 
ance of an efchar, produced by fome potential 
cautery ; the edges were hard and thick, and 
the fcrotum around it much inflamed. The 
urethra, and every other part of the penis 
had entirely efcaped the infedion; from 
which circumdance he did not fufped the 
nature of his complaint, till the inguinal 
glands enlarged and became painful. Proper 


externals and acourfe of an ti-venereal s effeded 
a cure in thirty-two days. 



Ab out two years ago, a lady applied 
to me in confequence cf a fore throat, 
which had for fome weeks been extremely 

G 2 troublefome. 


troublefome, notwithstanding the variety of 
gargarifms, &c. that had been ufed in ex¬ 
pectation of its removal. Upon infpeCting 
her throat, I pronounced the ulceration there 
to be venereal, and was confirmed in that 
opinion, when fhe informed me, that her reft 
of late had been greatly difturbed by noCturnal 
head-achs ; fhe however was at the fame time 
entirely at a lofs to account for thefe fymp- 
toms, the pudendum having never been dif- 
eafed. The infection, I faid, had in this cafe 
moft probably been conveyed by the tongue, 
and therefore I defired to know whether fhe 
had kified columbatini; to which fhe an- 
fwered in the affirmative, and jocofely obfer- 
ved, that fuch confequences might be added 
to the many other cogent reafons for keeping 
that member within its proper limits. She 
then entered upon a courfe of alterants, and 
was cured in about five weeks. 

The infection may be communicated like-* 
wife by contaminated femen, without injure 
ing the pudendum in its paflage to the uterus, 
from whence its poifonous particles may be 
abforbed, and by means of the lymphatics 


C 45 I 

conveyed to the blood, and thereby to every 
part of the body, 


A gentleman in the vicinity of London, 
about five years fince, confulted me upon the 
ill-ftate of health which himfelf and lady at 
that time laboured under. He informed 
me of his having led a very irregular life for 
fome years previous to matrimony, that he 
had been frequently difeafed, and recolledted 
having had chancres a few weeks before his 
marriage, which being removed by mercurial 
ointment and cathartics, at length he was 
fuppofed to be cured, and foon after entered 
into the holy ftate : in about five months his 
wife was thought to be pregnant from the 
fuppreffion of the menftrual evacuation, and 
the family felicitated themfelves thereupon; 
but the other concomitant fymptoms not at¬ 
tending in proper time, the parties were 
greatly difappointed, and particularly fo, to 
find that in lieu thereof, the lady’s health as 
well as that of her hulband, was evidently 
on the decline. A flow fever, want of appe- 

[ 4 * ] 

iite, ftrength, and fpirits foon after fucceeded, 
together with that of deep in the night, be¬ 
ing generally drowfy in the day time. Me¬ 
dicines of various kinds had been admi- 
niflered without producing the defired effeft ; 
the gentleman had an eruption upon his bread: 
and other parts of the body, which was en- 

I C 1*1 

couraged by the faculty, in expectation of its 
being critical; they were however, greatly 
miflaken, as none of the other fymptoms 
disappeared in confcquence of it. The lady 
ftill continued in a very languid date, not- 
withftanding the number arid variety of me¬ 
dical prefcriptions. In this unhappy fitua- 
tion they remained for fome weeks, when an 
old bottle companion paid the gentleman a 
viiit, and obferving fome of the eruption on 
his forehead, faid, c< I’ll be d--m--d if you’ve 
not got a corona veneris, your cafe has been 
moft egregioufly mi hake n ♦ pray lofe no more 
time, and give me leave to fend my furgeon 
to you f he acquiefced, and I waited upon 
him the next morning, when I found that 

his difeafe was moft evidently venereal from 

r • 

many other fymptoms, as well as the erup¬ 
tion which was of the true copper colour. 

3 ' Upon 

1 47 ] 

Upon examining the lady, her tkin in fume 
places appeared rather dileoloured, (as if na¬ 
ture was labouring to throw off part of the 
noxious humour that way, but wanted ftrength 
to effedt it) and (he had likewife every fymp- 
tom of a pocky hedtick. The difeafe had 
been communicated to her entirely by the 
contaminated femen of the man, without its 
having done the lead: injury to the vagina, or 
any other part of the pudendum. After hav¬ 
ing made the neceffary enquiries, I recom¬ 
mended a courfe of alteratives to both man 
and wife, by the ufe of which, in Jefs than 
two months they were perfectly cured, as ap¬ 
pears at this time by the healthinefs pf their 
offspring. The lady became pregnant about 
two months after leaving off the medicines, 
and has borne feveral children fince. Had 
this gentleman adopted the falutarv plan pur- 
fued by fome of our modern debauchees, 
prior to entering into the connubial ftate, all 
the foregoing difagreeables would have been 
prevented. This prudent plan or mcafure, 
is nothing more than going through a fliort 
courfe of alteratives 3 which in many in- 
ftances muff be highly neceffary, particularly 


[ 4 ^ ] 

after a feries of irregularities, and a variety 
of infedions, which through negled or im¬ 
proper treatment, may be produdive of great 
mifchief in future. 

The inefficacy of a firft or fecond faliva- 
tion occurring fo very frequently, I do not 
think thofe cafes worthy of infertion here, I 
ihall therefore immediately proceed to the re¬ 
lation of fuch ,as have withftood three, four 
or five repetitions of that foul procefs. 




In the year 1775, a gentleman in the city 
of London put himfelf under my care, on 
account of a confirmed pox, with which he 
had been infeded fome years, notwithftand- 
ing three falivations, and long courfes of the 
folution of corrofive fublimate and farfaparilla 
decodions.—He gave the following parti¬ 
culars of his cafe ; that he contraded the in- 
fedion in the year 1769, which at that time 
manifefted itfelf in a clap and chancres ; his 
furgeon admin iftered medicines for eight or 
nine weeks, and then difmiffed him as cured. 


[ 49 ] 

In the courfe of a few months a foul erup¬ 
tion overfpread his body, and ulcers formed 
in his throat; he again applied to the fur- 
geon, who advifed falivation, and foon after 
put him in a courfe of fpitting for forne 
weeks, and then pronounced his cure to be 
radical. In lefs than fix months the difeafe 
re-appeared, but with much greater malignity 
than before: the ulcer in the throat broke 
out afrelh, with the addition of two in the 
nofe, which foon fwelled to fuch a degree, 
as to obftrudt in fome meafure the fight of 
the left eye, and he was deprived of reft by 
nofturnal pains. Thus circumftanced, he 
employed another furgeon, who alfo falivated 
him; the fpitting he faid was continued above 
three weeks longer than in the preceding fa¬ 
livation, after which he was allured by his 
medical friend, that the difeafe was perfeftly 
removed. Bufinefs fome months afterwards 
required his taking a journey into the North, 
where he was alarmed with the return of 
fome of his former fymptoms, nocturnal 
pains, &c. During his refidence in the coun¬ 
try, he took a great deal of mercury in various 
forms and preparations for feveral weeks; 

H winch 

[ 5 ° 1 

which proving to be merely palliative, he 
returned to town and confulted another fur¬ 
geon, who recommended a third falivation; 
this he did not very readily agree to, having 
experienced its inefficacy twice before. How¬ 
ever, being informed that it was the dernier 
refource, and at the fame time entertaining 
a very high opinion of the abilities and inte¬ 
grity of his furgeon, he at length confented 
to be falivated a third time ; when a copious' 
fpitting was continued for a confiderable time, 
as long as it could with any degree of either 
fafety or propriety be purfued. 

He was attended likewife by a phyfician, 
who, with the furgeon, declared that the dif* 
eafe was entirely vanquiffied, and that nothing 
more was neceffary than pure air and nutri¬ 
tious diet to recruit his ftrength, and finally 

K ■ i 

complete the cure. Indeed they were, he 
faid, quite pofitive as to the fuccefs of this 
I aft falivation, the fymptoms having given 
way fo readily, and the procefs in every re- 
fpefl been fo fatisfaclorily conducted through¬ 
out. The patient acquiefced rfi the^prog- 
noftic, and without further delay removed 


C 5 r - 3 

into the country for the benefit of air, 
&c. This pleafing delufion lafted not nlany 
months, for he had the mortification to per¬ 
ceive that fome of the fymptoms of his old 
difoder were gradually coming forward again; 
he thereupon confulted his phyfician once 
more, by whofe dire&ion he took fublimate 

folution and farfaparilla for fome months : 

▲ * 

thefe medicines afforded him only a temporary 
relief, and were not attended with better 
fuccefs than the three falivations which had 
preceded them, as evidently appeared not 
many months after by a return of the difeafe. 
His patience as well as conflitution was by 
this time nearly exhaufted; infomuch that 
he frequently declared, no one fhould ever 
perfuade him to make any further trial of 
medicine, it having fo repeatedly proved fal¬ 
lacious. .The difeafe however becoming al- 
moft infupportable, he was prevailed upon to 
make one effort more for its removal: in 
confequence of which he became my patient 
at the time above-mentioned, when he had 
feveral foul ulcers on the back, two in his 
nofe, one on the cheek, and another behind 
the right ear; his head was almoft covered 

H 2 with 

[ S 2 ] 

with fcabs, as was likewife the fcreturn: from 
all thefe illbed fuch naufeous effluvia, that 
his neareft relations and friends could not re¬ 
main in the fame room with him long at a 
time. Pains in his head and limbs prevented 
him from fleeping, except towards morning 
or in the day. His appetite, ftrength and 
Ipirits were fo much reduced, that he def- 
paired of relief from any thing but a total 
diffolution. After having attentively given 
ear to this melancholy detail of repeated dis¬ 
appointments, and examined the ulcers, &c. 
and made the proper enquiries relative to his 
former habit of body, or natural tempera¬ 
ment previous to the difeafe, I declared as 
rny opinion, that he might be cured by alte¬ 
ratives, if of the moft powerful kind, and 
regularly perfevered in for fome weeks. He 
affented, though not without firft obferving, 
that by this time he had entirely loll all faith 
in medicine. I prepared for him ftrong de¬ 
coctions of the woods, and likewife alterative 
pills, and deb red him to take them in fuch 
dofes, and as repeatedly as the ftrength of his 
ftomach would admit of. Relying folely on 
the effedts of internals, I applied no other 


E S 3 ] . 

dreffing to the ulcers than dry lint through-¬ 
out the whole time. I recommended diet of 
the moft nutritious kind, and that it ihould 
be taken in fmall quantities, frequently re¬ 
peated, by reafon of the very weak State to 
which the difeafe and reiterated falivations 
had reduced him. In little better than a 
week, the nodturnal pains entirely left him, 
the fcabs foon after fell off, and the ulcers 
were in good condition; his appetite and fpi- 
rits daily encreafed, infomuch that he thought 
himfelf well in lefs than a month, the ulcers 
being all healed, and every fymptom of the 
difeafe having by that time difappeared.—Not¬ 
withstanding which, I judged it neceffiuy to 
continue the medicines a month longer, to 
prevent a relapfe. My patient had no ob¬ 
jection to perfevere in the ufe of them for any 
length of time, having already experienced 
fuch falutary effefts; which, with great plea- 
fure he con trailed to thofe of the methods he 
had formerly purfued ; inftead of being con¬ 
fined to his chamber, and undergoing one of 
the greateSt punishments (as he expreiled it) 
in the power of the faculty to inflidt, namely, 
that naufeous pfocefs a falivation, he had 


[ 54 ] 

enjoyed moderate exercife in the open air every 
day the whole time he was under cure, and 
experienced an encreafe of appetite, ftrength 
and fpirits in proportion to the time of ufing 
the medicines ; and as a proof of their not 
being unpleafant, he conftantly drank the 
apozem at meals, and at other times when 
thirfty. Thus was he radically cured in the 
fpace of two months, having never experi¬ 
enced any return of the complaint, as he not 
long fmee informed me. 


Three years fince, a merchant in Weft- 
minfter employed me to extricate him from 
the following difagreeables ; nodes on the 
Alins, an ulcer in the throat, noTurnal pains, 
and a fcabby eruption on his body, which 
from its ftench was extremely offenlive. He 
was much emaciated, and had little or no ap¬ 
petite. I defired to be informed of particu¬ 
lars, the date of the difeafe, in what manner 
it firft appeared, and what methods had been 
ufed for its removal. To which he replied, 
that in the year 177Z he caught the infection 


[ 55 3 

which made its firft appearance in a bubo on 
the right groin, and was not preceded by ei¬ 
ther chancre or clap, nor had he ever been 
infefted before. The tumor encreafed very 
faft and was extremely painful, his furgeon 
encouraged fuppuration, and when that was 
complete, opened it by cauftic. The dis¬ 
charge continued upwards of three months, 
during which time he rubbed in large quan¬ 
tities of mercurial ointment, and was purged 
at intervals to prevent a fore mouth; and 
at the end of about fourteen weeks his cure 
was pronounced. In a few months however, 
the difeafe returned; ulcers having formed in 
the throat, accompanied with nodturnal pains 
in his head and limbs, for which he under¬ 
went a falivation, and was again fuppofed to 
have received a cure; but in lefs than fix 
months he was obliged to apply once more to 
his furgeon, the difeafe having re-appeared 
with the addition of a node on the left fhin- 
bone; he was falivated a fecond time, and , 
was faid to be perfectly cured. After fome 
months the difeafe again appeared, when he 
employed another furgeon who perfuaded him 
to make trial of falivation for the third time, 

? which 


D j« ] 

Which affording only a temporary relief, he 
confulted a phyfician, by whofe diredion he 
took medicines for feveral months, until the 
difeafe was thought to be removed ; being 
reduced by this procefs to a very languid date, 
country air and als’s milk was recommended, 
but they had not the defired effed $ for foon 
after the difcontinuance of anti-venereals, he 
gradually relapfed into his former fituation. 
His medical friends being again confulted, 
they ftrongly urged the necdlity of a fourth 
falivation, as the only probable means of fuc- 
ceeding; by this time he entertained no very 
high opinion of falivation, but being almoft 
worn out with pain and difappointment, he 
agreed to it with this provifo, that it fhould 

he carried to fuch a degree, as to terminate in 


the perfed re-eflablilhment of his health, or 
in the grand cure of all mortal complaints. 
To humour him they acquiefced in the pro- 
pofal, and he was falivated for the fourth time; 
the fpitting they affured him was continued 
as long, and to as great a degree as his ftrength 
poffibly could admit of ; and every circum- 
ffance confidered, they had not the leaft reafon 
to doubt but a radical cure would be the con- 

lea uence. 

[ 57 1 

fequence. This defireable prediction how^ 
ever, was by no means verified, as evidently 
appeared in the courfe of a few months, the 
difeafe returning with feemingly accumulated 
virulence, which he obferved to be the cafe 
after each of the preceding falivations. Hav¬ 
ing finifhed the narrative* he defired to be 
informed whether I could render him any 
fervice, which he was induced to believe 
might happen, from fome accounts he had 
lately heard of my having effedled cures after 
the failure of repeated falivations. I told 
him that I had been fuccefsful in that line, 
and notwithflanding the obftinacy of his dif- 
eafe* I entertained fome hopes of relieving 
him. After fome further converfation, he 
defired me to adminiftei* what I thought pro¬ 
per, and that he would flridtly obferve my 
directions in every refpedt. Accordingly, I 
recommended a courfe of alteratives; and at 
the fame time the moft nutritious diet, with! 
moderate exercife in the open air, to be fre¬ 
quently repeated, proportionably to his en- 
creafe of ftrength. Within the firft fortnight 

* ^ x~ 

I fent him three times to a bagnio, in order 
both to cleanfe the ikin and promote perfpi- 

I rationc 

[ 5 8 1 

ration. By thefe means he obtained a per¬ 
fect cure in the fpace of ten weeks, and ha$ 
remained healthy ever fince. 


A gentleman in the county of Cornwall, 
four years ago, put himfelf under my care, 
his cafe was a confirmed pox, under which 
he had laboured near eight years, the fymp- 
toms at times having been palliated by five 
falivations, and a variety of medicines. Upon 
my requefting to be informed of every par¬ 
ticular relative to his complaint, he told me, 

* that being a man of few words, he never 
dealt in long narrations, of which his cafe 
would prove one if given in detail ; he fhould 
therefore mention a few of the moft material 
circumftances, and wrap them up in very 
fmall compafs. He faid, “ That about eight 
years before, he contracted a fmall chancre 
on the penis near the fraenum, which his 
furgeon healed in a few days by the ufe of 
mercurials both externally and internally. A 
fhort time after, a bubo formed in the groin; 
it fuppurated, was opened by cauftic, and, 


£ 59 1 

after difcharging fotne weeks, healed; lie 
took medicines fix or eight weeks, and was 
faid to be cured. In the courfe of a few 
months he was vifited by an ulcer in the 
throat, nodes, and noCturnal pains. In fine, 
the inveteracy of his difeafe was fuch, that, 
from the time above-mentioned, to that in 
which he was fpeaking, it had withflood five 
falivations, and great quantities of different 
medicines adminiftered between each of them: 
and (as hd expreffed it) had he not had the 
conftitution of a horfe, the difeafe or the 
methods ufed for its removal, muff in that 
length of time have deftroyed him; but 
thanks to heaven, his ftamina were naturally 
of the ftrongeft kind. He was now quite 
emaciated and. worn down with nodurnal 
pains in his head, limbs, &c. There were 
three nodes on his ribs, and a large ulcer 
on the head, from whence feveral pieces of 
bone had exfoliated, and many more were fo 
loofe as to require extraction foon after he be¬ 
came my patient j this opening had been 
made by a cauftic, for the purpofe of dis¬ 
charging a large collection of matter. Thefe 
were his fymptoms at the time he made ap- 

I '2 plication 

[ 6o ) 

plication to me; and notwithstanding the 
meafures hitherto adopted had fucceeded no 
better than as mere palliatives, I defpaired not 
of removing the difeafe; having fo frequently 
experienced the powerful effedts of alterants 
in the moft confirmed cafes, where many 
repeated falivations had proved abortive. This 
gentleman, acquired a radical cure in three 
months by the ufe of alteratives : had the ex¬ 
foliations been completed fooner, 1 fhould not 
have given him the medicines fo long. 

( \ *i I. . x.. J • *-*.-■ 

• • . CASE XXL 

In the year 1777, a gentleman from the 
county of York, came up to town to be un¬ 
der my care. He had been affiidted with a 
venereal complaint almoft ever fince his birth, 
by means of an infedted nurfe, whofe foul 
milk fo gradually affedted him, that fome 
weeks elapfed before his parents were able to 
account for his declining ftate of health; 
happily however, the caufe was difcovered, 
and a check put to the rapid progrefs of the 
difeafe, by means of anti-venereals. The 
growth however of the child was much 


[ 6i ] 

Impeded, as the medicines though continued 
a long time had only palliated the fymptoms, 
and faved the life of the patient. When he 
confulted me, his age did not exceed twenty 
years, he carried but little flefh, and was low 
•in ftature, although his parents were the re- 
verfe. Foul eruptions , frequently infefted 
many parts of his body, and fometimes af¬ 
forded 7 a temporary relief from the achs 
and pains which he generally‘at other times 
experienced. His eyes were extremely weak, 
and often fo much effected by this acrid hu¬ 
mour, as to be threatened with a lofs of fight. 
The infection having been thus deeply rooted 
in the conftitution, and in a manner inter¬ 
woven with it from his infancy, I entertained 
very flender hopes of totally eradicating it; 
this opinion I communicated to my patient, 
who, neverthelefs, entered very chearfully 
upon a courfe of my medicines, which fome 
of his acquaintance had frequently given him a 
very favourable account of. , In the fpace of 
three weeks he acquired a good appetite; the 
cutaneous eruptions gradually gave way, as 
did likewife the pains in his limbs, &c. he 
daily improved in ftrength and fpirits, and at 


[ 62 ] 

the end of three months appeared to be in 
high health, and was grown fat. By my ad¬ 
vice he continued the medicines three months 
longer, and was then perfeftly cured. Let 
this, amongft many other ffmilar inffances, 
ferve as a caution to parents how they entruft 
their infant offspring to mercenaries. Other 
acrid humours may often be derived from the 
fame unhappy fource. 

j • ‘ . r * « , 


A tradesman in Weftminfter, about two 
years and a half fince, became my patient, to¬ 
gether with his wife and child, who, at that 
time, were all infe&ed with the venereal dif- 
eafe: the man had a copper-coloured erup¬ 
tion on his body, and an ulcer in the throat; 
the woman a bubo in the right groin, and 
nodlurnal pains; and the child a venereal 
eruption which overfpread the greateft part 
of its body. This complicated fcene of dif- 

trefs took its rife from the hufband, who in- 

1 —* » 

formed me, that nine or ten months before, 
he had made an imprudent connexion; 
twelve days after which, a. fmall ulceration 

(a com- 

C 63 1 

(a common excoriation he fuppofed it to 
be, though in reality a chancre *) made its 
appearance on the glans penis, near the fras- 
nu'm; not fufpeCting it to be venereal, heap- 
plied a piece of dry lint or cotton, which 
healed it in a few days. On examining the 
part, I found, that notwithftanding it had 
ikinned over fo readily, there yet remained a 
fmall collofity, from which all this mifchief 
had originated. In the courfe of a few months 
he had reafon to fulpect himfelf to be in- 
feCted, and a Ihort time after the mortifica¬ 
tion to find that he had communicated the 
difeafe to his wife, from whofe milk it was 


conveyed to the child alfo. An enlargement 
of the inguinal gland was the firft venereal 
fymptom that attacked the woman, none of 
the neighbouring parts having been at all af¬ 
fected ; we may therefore conclude, that (lie 
received the infection from the contaminated 
femen of the man. The family furgeonand, 
apothecary having for fome time adminiftered 
medicines .without the defired effeCt; I was 

* By the patient’s account not much larger than a 
join’s head, 


t «* ] 

thereupon called in, and found the parties it* 
the fituation as above 'defcribed. The child 
at this time was'not more than twelve months 
old, confequently very little fiiccefs could be 
expedted from the application of medicine 
immediately to the infant itfelf, for, let the 
preparation be ever fo palatable to the tafte* 
or gentle in its effects, a fufficient quantity 
would lidt be taken to eradicate a difeafe of 
this kind. Therefore* I defired the mother 
to continue fuckling her child, that the re¬ 
medy might be conveyed to it through the 
fame channel that had communicated the 
difeafe ; for this purpofe, I immediately put 
her under a courfe of alteratives, of which 
(lie could take only fmall dofes on account 
of the infant, whereby the cure was protrac¬ 
ted to near four months, at which period I 
had the faiisfadtion of feeing both mother 
and child perfectly freed from this loathfome 
difeafe. The man’s health was re-eftabliihed 
in half the time that had been requifite for 
the cure of his wife and child, by reafori of 
his taking the medicines in their full dofes. 

. ■ f ■ ,.. v • 

I C0ULI5 mention feveral cafes fimilar to 


the foregoing ones, was I not of opinion, 
3 that 

[ 65 ] V ; 

that they will elucidate the fubject as well 
as ten times their number. 

N. B. In the treatment of chancres, their 
callofity fhould be removed as expeditionfiv 
as poffible, to prevent the ill effe&s of ab- 
forption which will otherwife enfue. 

Excoriations on the glans penis and prae- 
putium of men, and on the labia pudendi, 
Vagina, &c. of women, have very frequently 
been treated in the moft erroneous manner; 
fome that were truly venereal, have been totally 
negledted, whilft others that arofe from very 
different caufes, have been fo carefully at¬ 
tended to, as almoft to endanger the life of 
the patient; .by the application of ftrongmer¬ 
curials, draltic purges, &c. Nor are inftances 
wanting, of perfons having been falivated on 
the like occafion. 


• ' 

Having treated hitherto on curatives only, 
let us now bellow a few thoughts upon pre¬ 
ventives. The doftrine of prevention, altho’ 

K it 


• t 66 ] 

it may not be coeval with the difeafe, is ne> 
verthelefs of confiderable antiquity: for the 
accomplishment of fo defirable a purpofe, a 
great variety of methods have been propofed; 
many of them are to the highelt degree ab- 
furd, and a few only that bear even the fern- 
blance of probability, particularly amongft 
thofe recommended by the ancients. During 
my attendance at the Jedures of medical pro- 
feilors feveral years fince, I have frequently 
been much entertained at the ingenuity with 
which this fubjed has been handled. .One 
of thefe gentlemen has ftrongly contended, 
that a mucilaginous or oleaginous application 
is the only topical one that can be depended 
upon; and in fupport of this opinion, expa¬ 
tiated on the power of emollient, and 
unduous remedies in correding or counter- 
ading the mod: acrid and corrofive fubftan- 
ces, by blunting their fpicula, and daeathing 
the acute angles, &c. thereof. Another pro - 
felfor perhaps equally learned, and probably, 
not inferior to the former in experience, in- 
lifts, that a ftrong alkali is the only thing 
which can effed this grand defideratum, and 
for this reafon, that in order to expel the ve- 


[ «7 ] 

' - •* t ~N 

nereal virus as expeditioufly as poffible, no¬ 
thing will be fo likely to anfwer that pur- 
pofe, as avmedicine of this kind, which im¬ 
mediately ftimulates the glands to fuch a de¬ 
gree, as to produce a very copious fecretion 
of their fluids, and thereby diflodge the 
enemy without either impediment or de¬ 
lay. With equal plaufibility, acids have been 
recommended by fome, and fpirits by others; 
not confidering that the pain, &c. arifing 
therefrom, would frequently injure as much, 
and perhaps fometimes more, than the difeafe 
which they were intended to guard againft. 

Very numerous have been the advocates 
for mercurial preparations, whilft feveral have 
given the preference to thofe of lead. Every 
man of experience, however, mull: acknow¬ 
ledge that theories in general (how fpecious 
foever they may appear) are, the major part 
of them, extremely defective, when put to the 
teft. I have myfelf feen a number of va¬ 
rious experiments made on the prefent fuh- 
ject; indeed, the line of practice in which 
for many years 1 have been materially engaged, 
has enabled me to profecute an enquiry of 

K 2 ( this 

[ 68 ] 

this kind to as great an extent as mod men 5 
and after all, I am perfuaded that very gentle 
ftimulants will anfwer the purpofe more ef¬ 
fectually than applications of any other fort • 
I am led to be of fuch an opinion from the 
very great fuccefs that has attended this mode 
of prefervation for feveral years pad \ thofe 
of my patients who have made the pro¬ 
per and timely ufe of a compofition of this 
kind, have not been infected, I believe, once 
in fifty times upon an average : which, con- 
fidering all circumdances, is as much as can 
be reafonably expected. Were I Jo aflert that 
any medicine or preparation is infallible, I 
fhould pay no great compliment to the under- 
dan ding of my readers, by advancing fo pal¬ 
pable a falfehood ; fuffice it to obferve, that 
fome of my friends entertain the highed opi¬ 
nion of this compofition, from the great and 
repeated rifks they have ran for many months 
fucceffively, without receiving the lead in¬ 
jury ; notwithdanding their fometimes copu¬ 
lating with fuch as they knew to be infedted 
at the time of action, 

To guard againd the infedtion, fome prac¬ 
titioners have thought it diffident to advife 



I hi 

the application of un&uous or other fubftances 
to the glans penis, in order to obftrud or 
dofe up the abforbent veflels or pores thereof, 
being of Opinion, that the enemy always gets 
admiffion that way: in oppofition to fuch 
do&rine, be it remembered, that chancres fre¬ 
quently fix upon other parts of the penis, and 
fometimes attack the fcrotum and its vici¬ 
nities, from which buboes have enfued, as 
appears in fome of the foregoing cafes, 


Of gleets bluing from the urethra, there 
are two fpecies upon which I propofe making 
fomeobfervations; namely, the venereal gleet, 
and the feminal one. The former is the dif- 
charge which fucceeds a clap; in other words, 
the running that continues after the removal 
of infedlion ; this djfeafe arifes from the ure¬ 
thral ulcerations not having been healed in pror 
per time, which may be occafioned by various 
means; for inftance, by too frequent repeti¬ 
tions of ftrong cathartics; by unctuous appli¬ 
cations long continued; by acrimonious hu¬ 
mours ; In fine, by any thing which relaxes 


' [ 7° J 

to too great a degree, or for too long a conti¬ 
nuance. The cure is often protra&ed by the 
Irregularity of the patient, who fometimes is 
kind enough to impute it to the mifinanage- 
ment of his furgeon$ and on the other hand, 
it may fo happen, as to be really the cafe. 
Some of the reafons affigned for the diffi¬ 
culty of curing ulcers on the legs, will hold 
good in thofe of the urethra : the fituation of 
both affording a depending orifice, or drain to 
the humours, which confequently will very 
readily flow down thereto; and when Nature 
has been accuftomed for a length of time to 
any particular evacuation, or the outlet there¬ 
of, the flux of humours will there be very 
confiderable, and the talk of diverting them 
to any other channel will be proportionably 
difficult. Another difagreeable eircumftance 
attending ulcerations of the urethra, is, the 
frequent flows of urine over them, which at 
times being highly acrimonious, mufi inter¬ 
rupt the digeftion of the ulcers; and a part 
of it lodging in them, may corrode in fome 
degree, unlefs prevented by proper topical ap¬ 
plications, which cannot here be conveyed in 
a more* fuitable, form than that of injection. 


[ 7* I; 

And even after the ulcers are healed, it will 
generally be found expedient to continue in¬ 
jection a week or ten days longer, to confirm 
the parts, and defend them from the urinous 
falts, which (fhould this precaution be omit¬ 
ted) are fometimes fo acrid as to abrade the 
new fkin, and make the fores difcharge afreih- 
The fame thing may happen when the urine 
is loaded with coarfe gravel or {tones, which 
will foon deftroy the. tender cicatrix; and if 
negleCted but for a few days, a fluxion of 
humours to the part may enfue, and mutt: 
confequently retard the cure. 

So high an opinion do I entertain of in¬ 
jections, that I will venture to affirm, that 
almoft every gleet (unaccompanied with ca¬ 
runcles, or callous edges of thofe ulcers from 
whence it proceeds) may be cured by injec¬ 
tion, provided the redundant acrimony (if 
there happened to be any) {hall have been pre- 
vioufly corrected. Innumerable almoft are 
the inftances which might be produced in 
fupport of this opinion; a few only of the 
mo ft remarkable ones will be here introduced 
to elucidate that point.—Gleets, attended with 


E 9% ] 

great obftrudtions in the urethra, occafioried 
by carnofities, caruncles, callofities, fungufes, 
&c. (call them by what names you pleafe) 
will generally require medicated bougies to 
temove them before we can expe£l a radical 
cure of the gleet* They will likewife be ne- 
ceffary in the removal of ftridtures, and the 
callous edges of old obftinate ulcers in this 
part* As to the compofition of bougies, great 
Care muft be had that nothing corrofive or 
very ftimUlating be introduced therein• on the 
contrary, it muft confift of the mildeft di* 
gpftives; and when formed into bougies, 
muft have a very even polifhed furface, and 
be of fuch temper or confiftence as readily to 
adapt themfelves to the curvatures, &c. of the 
urethra, and yet at the fame time be endued 
with fufficient ftrength to make the neceffary 
preffure* The foregoing caution relative to 
the compofition of bougies, cannot be too 
much inculcated, when we confider the de¬ 
licate texture of the urethra and its extreme 
irritability : no two parts of the body, I pre¬ 
fume, bear greater analogy in point of fenfi- 
bility, than the urethra to the eye. In the 
management of bougies, more attention is 
3 neceffary 

I 73 1 

fteceflary than people in general imagine ; for 
inftance, if too large a one be introduced, or 
too much force ufed, either an haemorrhage 
(that very much alarms the patient, though in 
other refpedts not prejudicial) or an inflam¬ 
mation enfiies, which muft retard the cure* 
fhould it produce no other difagreeable ef¬ 
fect. The diftention of thefe parts ought 
to be made very gradually for the reafons 
above affigned, as well as to avoid the pain 
that muft otherwife be otcafloned. If the 
end of the bougie be fuflfered to prefs againft 
the neck of the bladder, it generally ftimu- 
lates to fuch a degree, as to produce a ftran- 

A ligature of feme kind fhould alwavs 


be affixed to a bougie, previous to, or im¬ 
mediately after its introduction, both to pre¬ 
vent it from flipping into the bladder, and to 
retain it exadtly in the proper fituation. How 
long each bougie may be worn, will depend 
upon the irritation it occafions; it muft not 
remain in the urethra after it becomes painful, 
for reafons very obvious. When the urethra 
has been habituated to them, they' may be 

L retained 

[ 74 1 

retained the whole night, provided deep be 
not thereby prevented, or much interrupted. 
Antecedent to a courfe of bougies, it will fre¬ 
quently be neceflary to prepare the parts with 
a cooling injection, and to repeat it during 
the ufe of them, as foon as the lead fymptom 
of inflammation makes its appearance. Gen¬ 
tle aperients at this time may likewife be fer- 
viceable, fuch as lenitive electary, fulphur, 
magnefia, &c. Moderate exercife, and a to¬ 
tal abftinence from acids and ftrong liquors 
muft alfo be enjoined. As to the length of 
time which may be proper to continue the 
ufe of bougies, that muft depend upon the 
degree of obftruction in the paflage, and the 
irritability thereof, together with the patient’s 
habit of body, and many other circumftances. 
It will not I believe be difputed, that there 
may be the abufe, as well as proper ufe of 
bougies, for fhould they be continued long 
after the difappearance of difeharge, a frefh 
running will be produced, by the very means 
employed to remove the old one ; they are 
not, however, to be left oft abruptly; it 
muft be don zgradatim, left the cicatrix fhould 
exceed its due bounds, and thereby leflen the 


, • t 75 3 ' 

diameter of the urethra. Men fometimes 
want patience under a courfe of bougie; but 
the time may be greatly fhortened by the af- 
fi fiance of proper injections. Many inftances 
indeed have occurred, where injection has 
performed a cure after bougie, and every other 
remedy has proved ineffectual. Such im¬ 
provement has of late been made in this rc- 
fpeCt, that I do not find it neceffary to ufe half 
the number of bougies which I formerly did, 
cures now being effected in fo much lefs time. 


In the month of March, 1777, I was ap¬ 
plied to by a gentleman of fortune in the 
county of Derby, who had laboured under 
a venereal gleet for more than fix years; in 
the courfe of which time he had employed 
feveral of the faculty in his own neighbour¬ 
hood, and had made journies to town for the 
opinions and prefcriptions of fome eminent 
ones in the metropolis, in confequence where¬ 
of, he had ufed a variety of medicines both 
external and internal, which afforded him 
only a temporary relief ; the di(charge gene- 

L 2 rally 

r 76 ] 

rally returning in ten days or a fortnight after-* 
wards. The difeafe commenced, he faid, in the 
year 1770, when he contracted a clap, for the 
cure of which, his furgeon had purged him 
pretty briildy, and ufed a confiderable quan¬ 
tity of mercurial ointment, until the infec¬ 
tion was fuppofed to be removed ; then, bal- 
famics, aftringents, &c. &c. were adminif- 
tered ; and he afterwards ufed the cold bath 
for feveral weeks fucceffively. All thefe ex¬ 
pedients however proved merely palliative, 
as the complaint conftantly returned foon 
after their difcontinuance. The d'ifcharge 
was copious and of a deep yellow colour; 
I deiired permiffion to examine the urethra 
with a bougie, he readily affented, but ob- 
ferved that bougies would be of no fervice to 
him, having ufed them upwards of eleven 
months without any good effeCt; I informed 
him that 1 did not propofe his wearing them, 
unlefs there Ihould be a very material ob- 
ftruClion in the pafiage; which upon examir 
nation not being the cafe, I recommended 
alteratives and an aftringent injection, the 
former to be continued three weeks or a 
month, and the latter, double that time— 



[ 77 1 

with moderate exercife, and a ftriCt abftinence 
from acids of every kind: and at the fame 
time to keep his body folutive with fulphur 
or magnefia alba. By thefe means he was ra¬ 
dically cured in the fpace of two months, 
and has remained well ever fmce, as he per- 
fonally informed me in the month of January, 


X * , • 

- ■' . 

About two years fince, a gentleman in 
Weftminfter applied to me for the removal 
of a gleet, which had troubled him twelve 
years ; during that time, he h~d at intervals 
taken a great deal of medicine, and of various 
kinds. One remarkable circumftance attend¬ 
ing this cafe, was, that notwithHanding the 
very long continuance of the running, no 
carnofities or obftructions of any fort had 
formed in the urethra, which I afcertained 
by the introduction of a bougie, previous to 
delivering any opinion upon it ; when finding 
the paflage perfectly clear, I told my patient 
that his complaint in all probability might 
fie removed without much difficulty,, pro¬ 

[ 7 * 1 

vided he would live temperately, and adhere 
ftrictly to the rules I fhould preferibe ; 
namely, to avoid acids, flrong liquors, and 
violent exercife; and regularly to ufe every 
night and morning a fyringeful of inject 
tion. Thefe he did; and was perfe&ly cured' 
in the courfe of three months, 


A noble Lord, in the month of May, 1778, 
fent for me, on account of a gleet attended 
with a fmall obftruffion in the urethra: he 
informed me that his diforder was of four 
years Handing, and had refilled every means 
preferibed for its removal; that he had taken 
a variety of medicines, been once falivated, 
and had ufed bougies. The difeharge was 
thin, yellow, and copious, unaccompanied 
with either pain or inflammation. As his 
Lordfhip was of a good habit of body, I 
did not preferibe any internal remedies, but 
trufted wholly to inje&ion, which in the’fpace 
of fix weeks effected a radical cure. 

N. B. The 

[ 79 ] 

N. B. The fame regimen was obferved as 
in the preceding cafe, and the injection was 
ufed three times each day. 


A stationer in Weftminffer, three years 
ago, applied to me, in confequence of a gleet 
with a finall caruncle in the urinary canal, 
which complaint he had laboured under up¬ 
wards of five years, and during that time had 
ufed various medicines, but they had all 
proved ineffectual: he was however, perfectly 
cured in lefs than two months, merely by the 

ufe of injeCtion. 

M 0 

• C _ A S E XXVII. 

, - I *. v 

I was confulted about two years fince by 
a coal-merchant in the county of Middlefex, 
who had then contracted a virulent gonorrhoea, 
in addition to an old gleet with which he had 
been troubled for- fome years. He expreffed 
much concern at this accident, imagining 
that the gleet would be a great impediment 
to the cure of the gonorrhoea; but I foon 



[ So ] 

made him eafy on that head, by obferving ? 
that probably both complaints would be re¬ 
moved at the fame time, as I had very fre¬ 
quently been fortunate enough to cure clap 
and gleet both together: and indeed it fo 
happened in this cafe, at the end of five 
weeks, by means of injedion and an alterative 


About feventeen months ago, an Irhh 
Peer became my patient; his cafe was a ve¬ 
nereal gleet, with which he had been afflided 
many years : bougies as well as internal me¬ 
dicines had been repeatedly ufed without fuc- 
cefs. Upon examination I found a fmall 
carnofity in the urethra, from which iffued a 
moderate quantity of yellow matter. I pro- 
pofed injedion, but he at firfi: objeded to it, 
alledging his having tried it without efted ; 
not confidering (as I obferved to him) that 
the compofition of injedions were as likely to 
vary as that of any other remedy. I likewife 
related to him fome inftances wherein that 
mode of cure had been particularly fuccefsful 
3 after 

[ «■ ] 

after every other had proved the reverfe. Hd 
thereupon agreed to put it once more to the 
teft, but was obliged to defer it for a few weeks 
on account of a long journey he was the next 
day to fet out upon. In the courfe of a month 
his lordfhip returned, and then informed me 
that my attendance was doubly neceffary 
to him j having, on the journey, added a clap 
to the old diforder. The running was plen¬ 
tiful, and accompanied with a heat of urine 

and chordee. 


I immediately recommended the ufe of 
injedtion and a few alterative pills, which, 
with a proper regimen, perfedtly cured him 
of both clap and gleet in the fpace of thirty- 
two days. 

From the number of cafes that I have 
feen fimilar to the preceding ones, where a 
frefh infedtion has been engrafted upon an 
old gleet, and the little difficulty generally 
experienced in removing both together, I am 
led to believe, that in many inftances, the fti- 
mulus produced by the venereal virus, has fre¬ 
quently contributed to accelerate the cure of 
the gleet; and particularly fo, when it fixes 

M immediately 

• V 

[ 8 * ] 

immediately upon the old ulcer ; whofe cal¬ 
lous edges may thus be removed more fpeedily 
perhaps than by any other means. 


A very ftriking inftance of this kind will 
be found in the fubfequent cafe: 


Four years fince, a linen-draper in the 
city, after having ineffectually employed fe- 
veral gentlemen of the faculty for the re¬ 
moval of a venereal gleet which had troubled 


him eight years, made application to me for 
the fame purpofe. I examined the urethra 
with a bougie, and found very little obftruc- 
tion therein; I then enquired into the dif¬ 
ferent methods of cure that had been adopted 
by his other furgeons, to which he replied, 
that after going through feveral mercurial 
courfes, taking 4 great quantity of balfamics, 
and ufing a variety of aflringents internally as 
well as topically, bougies were at laft recom¬ 
mended ; and notwithilanding the uninter¬ 
rupted application of them for fome months, 
and the ftrideft regimen at the fame time 



[ 8 3 3 

being ohferved, the difeafe Hill maintained 
its ground. Upon further enquiry, I found 
that my patient was a very temperate man, 
and rather of a cold phlegmatic habit; I 
v therefore judged that an alteration in his mode 
of living might be of life, and accordingly 
prefcribed half a pint of good port wine to 
be taken every day after dinner, and twice or 
thrice that quantity after fupper. I likewife 
ordered an inje&ion to be ufed night and 
morning, and a few internal alteratives. This 
plan was purfued for a fortnight or three 
weeks without producing any very material 
alteration in the difeafe; his fpirits and appe¬ 
tite however were greatly benefitted, infomuch, 
that in the courfe of a week or ten days longer 
perfeverance therein, he was induced once 
more to pay his devoirs at the fhrine of Venus, 
and there again became a burnt- offering, having 
then acquired both clap and chancres. His 
* reward for Healing fire (if it may be deemed 
a theft) differed widely from that which Pro¬ 
metheus experienced: for to his great joy 
and furprife, the old inveterate gleet was ra¬ 
dically cured by the means ufed to remove 
the gonorrhoea and chancres, in the courfe of 

M 2 twenty- 

[ « 4 ] 

twenty-nine days. It may be afkcd, whether 
no fuccedaneum can be invented to anfwer 
the purpofe as well as venereal matter? To 
which I ihould only give this anfwer, let 
future experiments and obfervations afcertain 
that point. It may like wife be fuggefted, that 
the fuppofed advantages accruing from this 
frefh infedtion, do not abfolutely arife there^ 
from, but from the medicines ufed in con- 
fequence of it, which may fo corredt the la¬ 
tent acrimony of the blood and juices, as to 
effedt a cure merely by that circumftance. 
My reply to this will be, that I have admi- 
niftered the fame kind of medicines, and for 
a longer time in fome of thefe cafes, previous 
to the new infedtion. It may then perhaps 
be faid, that they were not continued long 
enough: be it fo; or at this rate we might 
go on ad infinitum , and never put a period to 
our fuppoiitions; we will therefore leave to 
practice inftead of theory, the determination 
of this matter. 


I was confulted a few years ago by the 
captain of a marching regiment, who had 


[ ] 

been afflidted many years with obftru&ions in 
the urethra—they were particularly diftreffing 
to him during the late war, occafioning re¬ 
peated fuppreffions of urine, which at length 
became fo frequent, as to oblige him to carry 
a fmall catheter or a bougie generally in his 
pocket j unluckily, however, he was unpro¬ 
vided in that refpe£l once upon a forced 
march, when being attacked with a total fup- 
preffion of urine, and having no affiftance at 
hand, he was under the neceffity of taking a 
fmall twig from a tree, and after properly 
fhaping, forced it through the obftrudtions 
into the bladder, made a paffage for the urine, 
and thereby faved his life, which had often 
been in the moll imminent danger from the 
fame caufe. 

At the time he applied to me, the urethra 
was fo much obftrudted with caruncles, that 
I found great difficulty in paffing the fmalleft 
bougie, and therefore recommended the im¬ 
mediate application of them: his anfwer was, 
“ That if no other means were ufed, he was 
yery certain no cure would be obtained, hav¬ 
ing worn bougies at times for fomeyears paft 

I replied. 

[ 86 ] 

I replied, “ That internal remedies were like- 
wife indifpenfably neceffary in his cafe, by 
reafon of the very high degree of fcurvy with 
which he was molt evidently infefted; his body 
being almoft covered with puftules, boils and 
fcabs, the ranked: of th£ kind that I had ever 
feen. Very powerful antifcorbutics were 
therefore liberally aaminiftered during the 
whole courfe of bougie, in order to correct 
that acrimony, which would otherwife have 
much impeded, if not entirely prevented the 
formation of a proper cicatrix. The difcharge 
from the urethra was very plentiful for the 
firft three weeks, and from its fharpnefs fome- 
times inflamed the glans penis and praputium, 
as well as the urinary duCt, but was kept 
within bounds by the ufe of emollient and 
cooling injections. Tlius, was the urethra 
entirely cleared of obftruCtions, the body of 
its acrimonious humour, and in lefs than four 
months the patient’s health perfectly re-efta- 
bl iflied. 

— i...s , ‘‘A 

C . A S E XXXI. 

A member of the Houfe of Commons 
about a year ago font for me, on account of 


[ 8 7 ] 

an obflm&ion in the urethra, which had 
troubled him fome years, and of late pro- 
duced a frequent inclination to make urine, 
though it could flow now only in a very 
fmall it ream, and with much difficulty, from 
the encreafed iize of the carnofity. The ob- 
ftru£tion was fo great, that it would not ad¬ 
mit the fmaHeft bougie to pafs it; I therefore 
contented myfelf with introducing one up to 
the caruncle, upon which it made a gentle 
preffure, being properly fixed with a ligature: 
I gave diredions for its being retained in the 
fame pofition as long as poffible, that the 
bougie might gradually either infinuate itfelf 
through this flefhy fubftance, or elfe flip pad 
it. My patient perfevered in the method I 
had propofed for the fpace of near eleven 
hours, when he had the fatisfaftion of per¬ 
ceiving that the obdruclion gave way to the 
bougie. A fmall hccmorrhage enfued, which 
in a few minutes ceafed of itfelf—foon after¬ 
wards he attempted to make urine, but at fird 
found the palfage more obftrucled than ufual; 
however, upon draining, he forced out fome- 
thing, which he imagined was coagulated 
blood, but on examination it proved to be 



> ' </ 


[ 88 ] 

the carnofity itfelf— -in fhape and fize it nearly 
refembled a pea, and was compofed of a 
tough membranous fubftance,—the bafis of 
it was very fmall, as will be readily conceived 
from its being fo eafily feparated. The un- 
ufual frequency of making water immediately 
ceafed upon the removal of the excrefcence, 
which without doubt had fo ftimulated the 
parts as to be the occafion of it; upon the 
fame principle I prefume as any extraneous 
body would have done. Afixingent injeftions 
now became neceffary to procure a firm cica¬ 
trix $ bougies were likewife frequently intro¬ 
duced to preferve the natural diameter of the 
urethra in that particular part; and, in order 
to confirm the cure, thefe applications were 
continued about a week or ten days. 

I . \ * 

CASE xxxir. 

A tradesman in Weflminfter, was for 
feveral weeks incommoded with a frequent 
defire to void urine, which at length encreafed 
to fuch a degree as to prevent his attendance 
on bufinefs: thus circumftanced, he became 
my patient., Upon enquiry, I found that he 



t 89 ] 

had not beeii fiibjeft to either gravel or (tone, 
nor was there any reafon to fufpedl that 
infection had given rife to the complaint. I 
then propofed to examine the urethra with a 
bougie, but was prevented by a wart juft 
Within the orifice; that excrefcence I re¬ 
moved with fcifi'ors, and deftroyed its roots 
with an efcharotic. The patient informed 
me next day that he no longer felt any irri¬ 
tation at the neck of his bladder, nor had any 
inclination to urine oftener than lie ufuaily 
did before the diforder took place. The 


parts foon healed; and he has been free from 
ftrangury ever fince. 

. Here we may obferve, that a difeafe at one 
end of the urethra, will produce a di(agree¬ 
able fenfation at the other. It frequently 
happens that a ftone in the bladder, when it 
prefles in a particular direftion, will create 
fuch an itching at the glans penis and pros- 
putium, that the patient cannot refrain from 
rubbing and pulling thofe,parts. 

Excrescences in the urethra fometimes 
affefl very materially the feminal dufts, as 
will appear in forne of the following cafes. 

N It 

[ 9° ] 

It often occurs, even in claps, that the 
patient thinks his difeafe feated in one part 
of the urethra, when it happens to be in 
another: indeed, we cannot wonder at the 
many inftances of very great fympathy in 
thefe parts, when we confider their exquifite 


A gentleman in the county of Norfolk, 
had many years laboured under a difficulty of 
making urine, occafioned by excrefcences in 
the urethra, the confequence of a long con¬ 
tinued gleet. He had had frequent fuppref- 
fions of urine after violent exercife, hard 
drinking, or exceffes of any kind; this he 
deemed merely a temporary inconvenience, it 
having generally been foon removed by the 
introduction of a catheter ora bougie ; which 
circumftance rendered him negligent as to 
the making of proper application for a radical 
cure. However, he at laft fuffered very fe- 
verely for his inattention, as v/ill appear in 
the fequel. In the month of June, 1777, 
being very much heated with exercife and 


[ 9 * 3 • ' 

high living, he was attacked by his old com¬ 
plaint, (the fuppreffion of urine) and recourfe 
was immediately had to the former expe¬ 
dients, but the inflammation and obftru£fion 
were fo great, that no inftrument could 
be palled into the bladder—-his furgeon 
endeavoured to relieve him by the ufual 
means, fuch as bleeding, warm bathing, 
terebinthinate and other clyfliers, anodynes, 
&c. but they proved ineffectual. After the 
fupprefiion had continued upwards of thirty 
hours, he determined to come up to town, 
though at the diflance of more than one 
hundred miles. The anxiety and pain that 
he experienced during the journey, may be 
better imagined than defcribed. On his 
arrival in town he immediately fent for me, 
but half an hour before I law him, the urine 
had forced its way through the perineum, a 
part of which, and of the adjoining fcrotum* 
I found in a mortified (late.- The mortification 
extended at lead fix inches in circumference. 

i • _ 

From the pale emaciated afpedl of my pa¬ 
tient, I could not expert any great affiftance 
from his conftitution, which by his own ac- 


count had been much impaired by a long 
f . , N 2 fucceffion 

[ 9 3 1 

fucceffion of irregularities. His age did not 
exceed forty years; in the laft ten of which, 
he had been frequently attacked with fevere 
fits of the gout. All thefe circumftances 
confidered, I could not form the moft fa- 
vourable prognofis; hovv r ever, I was parti¬ 
cularly careful, that my opinion fhould not 
be couched in. fuch terms as might deprefs 
his fpirits ? being fully aware of the bad con- 
fequences that frequently enfue from the 
mind’s influence upon the body, efpecially in 
putrid complaints. Having in thefe cafes no 
•time to lofe, I immediately proceeded to fca- 
rify the parts as deeply as the nature of them 
would admit of, or as circumftances required. 
After ftuping the wound extremely well 
with a fpirituous fomentation, I applied warm 
digeftives, and over them (inftead of cata- 
plafm of any kind) foft rags moiftened with 
camphorated fpirjis, and ordered the nurfe 
to dip a fponge in the fame every half hour, 
and fqueeze it over the dreffings and the 
neighbouring parts, in order to prevent as 

much as poffible the mortification from ex- 


tending itfelf any further. The dreffings 
were often renewed, on account of the urine’s 


[ 93 1 

Sowing fo frequently through the wound. 
As internal antifeptics were likewife indift 
penfably neceffary, I prefcribed an ele&ary 
of Peruvian bark and Virginian fhake-root, 
to be taken as often and in as large dofes as 
his ftomach would bear, and that it fhould 
be wafhed down with camphorated julep or 
good Port wine, of both which I allowed 
him to take very freely. His liquors were 
moil of them acidulated with elixir of vi~ 
triol, to which was added the aromatic tinc¬ 
ture, to prevent its offending the ftomach, 
and at the fame time render it more cardiac. 

r , ' • 

There were likewife prepared for him ftrong 
rich foups, and what is called beef-tea, of 
which he drank plentifully. Opiates were 
adminiftered the frft twelve days, and at 

Jr * r 

fuitable intervals, clyfters to keep his bowels 
in a proper ftate. By thefe means the pro- 
grefs of the mortification was foon impeded, 
and in a fhort time entirely flopped. The 
Houghs began to feparate in the courfe of 
twelve days, when I thought it advifeable 
to attempt regaining the natural pafiage for 
the urine, the whole of which conftantfy 
Sowed through the wound ever face it had 

fir ft 

[ 94 3 

firft made an outlet that way. The caruncles 
in the urethra made fo much refiftance, that 
four days elapfed before the final left bougie 
could be palled through them; but as foon 
as that point was gained, a bougie was con- 
ftantly kept in the urethra both night and 
day. The urine by this method foon reco- 
vered the natural channel, and in lefs than a 
fortnight, not'a drop of it pafied through the 
wound, which now digefted well, and in a 
few days incarned, and foon after cicatrifed 
as kindly as could have been expefted. By 
continuing the bougies fix weeks longer, the 
urethra was entirely cleared of all its obftruc- 


lions, and the parts firmly healed. Soon 
afterwards, my patient returned to the coun¬ 
try in high fpirits, and in a much better ftate 
of health than he had been for many precede- 
isg months. 


Having hitherto made little or no men¬ 
tion of the feminal gleet, I will now offer a 
few obfervations upon the origin of that dif- 
cafe, and produce fome particular cafes, both 


[ 95 ] 

to illuftrate the fubjed:, and recommend a 
method of cure that has frequently fucceeded 
after every other had proved ineffe&ual. 
That feminal gleets or weakneffes (call them 
by which name you plealej are of all others, 
the moft difficult to cure, I prefume, will 
not be controverted by any experienced prac¬ 
titioner ; this difficulty will be encreafed in 
proportion to the immediate caufe of the dif- 
eafe, and the contingencies that may attend 
it, the habit of body, mode of living, clb 
mate, profeffion or occupation, &c. of the 
patient. The difeafe may arife from thofe 
excrcfcences in the urpthra, which we term 
caruncles, carnofities, &c. and it is fome- 
times occafioned by the deftrudion of that 
natural caruncle, the caput gallinagitm ure~ 
three. It originates likewife from an acri¬ 
monious date of the blood and juices. Some¬ 
times it is produced by a general relaxation 
of the whole frame, from whatever caufe 
foever that may take its rife, whether from a 
ferics of debaucheries, exceffive venery, feif- 
pollution, &c &c. 

In fome of the foregoing cafes, I have de- 

o o 

monflrated that an excrefcence in the urethra 



■' [ 9 6 i 

will ftimulate the bladder (though at the dif~ 
tance of fome inches) to fuch a degree as to 
bring on a frequent inclination to evacuate 
its contents : and when that ftimulus hap¬ 
pens to fix upon the feminal dufts, the re¬ 
fer voirs, or the tefticles themfelves, fimilar 
effe&s muft naturally be expected. After the 
feminals have been thus ftimulated for a 
length of time, their retentive faculties muft 
indubitably become fo much impaired and 
weakened, as to admit of very frequent and 
involuntary emifiions. The fame confe- 
quences may alfo be expected, when the blood 
is much impregnated with acrimony of any 
kind, and a confiderable fhare of it falls upon 
any particular organ (a gland for inftance, or 
its excretory du£t) the irritation thereby pro¬ 
duced muft excite an unnatural fecretion, as 
well as expuliion of that particular fluid, and 
will at the fame time alter the quality of it. A 
long cotinued repetition of this ftimulus gradu¬ 
ally relaxes the mouths of the excretory ducts, 
together with their valves or fphindters, thofe 
natural obftacles to involuntary evacuations; 
in fine, they entirely lofe their original powers 
of retention, and the fluid is frequently dif- 
3 • • charging 


[ 97 1 

t .5 . ^ 

cliarging itfelf, aimed as foon as fecerned; or 
upon the lead exertion in making urine or 
going to ftool, fuppofing the feminal veffels 
to have been thus vifited by the acrimonious 


An officer in the navy, after having la* 
boiired under a feniinal gleet for fix years and 
upwards, put himfelf under my care about 
two years and a half fince. His fpirits, 
drength, appetite, &c. were greatly reduced, 
infomuch, that he was threatened with a 
total lofs of virility. - After interrogating him 
as to the caufe of his difeafe, I examined the 
urethra with a bougie, and found it perfectly 
free from obdruftion : I then infpected the 
colour and confidence of the difcharge, and 
foon perceived that it had lod its- natural 
texture, and feemed to abound with acri¬ 
mony, which upon further enquiry proved to 
be fcorbutic. He informed me that he had 
been much afflifted with the fcurvy for fome 
years previous to the appearance cjf his prefent 
complaint. Having now invedigated the 

O caufe 

[ 92 ] 

caufe of the difeafe, I had but little difficulty 
to apprehend in performing the cure of it; 
as my patient, from his appearance, as well as 
promifes, perfuaded me, that nothing on his 
part would be wanting for the completion of 
it. I had not formed a wrong conjecture ; for 
with the greateft regularity and attention he 
perfevered in a ccurfe of antifcorbutics, 
which in a few months entirely removed his 
gleet, and at the fame time perfectly re-efla- 
blifhed his health in every other refpeCt. 


A gentleman in the county of Middle- 
fex, applied to me two years ago, on account 
of a ieminal gleet, to,which at times he had 
• been for fome years fubjeCt, though at inter¬ 
vals entirely free from it; his vigour there¬ 
fore was not very much impaired thereby, but 
as the returns of the complaint, had of late 
been more frequent than ufual, he began to 
be very apprehenfive of confequences. Upon 
examination, I found that the cauie of this 
gleet might be truly deemed arthritic; it was 
indeed fufficiently evident from the appear¬ 


[ 99 ] 

anceof the difcharge, and the patient’s own 
account of his cafe. The femen was loaded 
with a cretaceous matter, fimilar to the chalk 
ftones produced by the gout; in proof of 
which, he informed me that he had been 
afflicted with the gout many years, chalk 
ftones had appeared on his feet, but that no 
more of them had formed after the creta¬ 
ceous matter found its way to the fpermatic 
vefiels, and (as he very rationally fuppofed,) 
difcharged itfelf with the femen ever fince 
that period. Being perfectly fenfible that the 
difeafe originated from the gout, I recom¬ 
mended patience, and a refignation to his fate. 
This prefcription not fatisfying him, I pro- 
mifed to confider further upon his cafe, and 
exert my beft abilities to ferve him. After a 
little refleftion, there occurred to my memory 
the cafe of a gentleman, who fome years fmce 
employed me to cure him of the venereal 
difeafe, and as he was greatly afPiidted with 
the gout, requefted very earneftly that I would 
not give him the leaft particle of mercury; 

* I acquiefced therewith, and in the courfe of 
a few weeks removed his complaint, merely 
by the ufe of vegetables. . ; ? 

Q 2 Some- 


/ ' [ 100 ] r 

Sometime afterwards he informed me, that 
thefe medicines had fo purified his blood and 
juices, that the gout had not viiited him fo 
frequently as ufual, and the paroxyfms were 
much milder and of fhorter duration than 
they formerly had been. He has therefore 
taken the medicine fince that time as an anti- 
arthritic. The recolledtion of this circum- 
ftance induced me to adminifter remedies of 
a fimilar kind for the cure of this arthritic 
gleet ; and l had foon the fatisfa&ion of per¬ 
ceiving that the difcharge gradually decreafed, 
and was lefs and lefs impregnated with the 
chalk, hill it entirely difappeared, which 
happened in about two months : I advifed 
neverthelefs a continuance of the medicines 
fometime longer in order to prevent a re- 
lapfe. The medicines ufed upon this occafion 
were, diuretics and diaphoretics, in the com- 
pofition of which, camphor was no inconfi- 
derable ingredient. Before we difmifs the 
fubjedt, it may not be improper to mention 
fome other diforders, to which the organs of 
generation are liable, from this arthritic acri¬ 
mony. I have been informed from very good 
authority, of priapifms originating from the 


r ,, E 101 3 

fame fource; one in particular, of a gentle¬ 
man in the county of Surry, which is laid 
to have continued an incredible length of 
time. Inftances I have myfelf feen, where 
the gout has produced tumefactions of the 
tefticles, to as high a degree as thofe in ve¬ 
nereal cafes, and which, like them, have been 
removed by difcutient fomentations, and emol¬ 
lient cataplafms, affifted with powerful fudo- 
rifics internally. In thefe cafes opiates like- 
wife may repeatedly be adminiftered to very 

great advantage. 

• .. 


About eighteen months fince, I was con- 
fulted by an eminent artift in the vicinity of 
London, who had for many years been trou¬ 
bled with a gleet and obftruCtions in the uri¬ 
nary paffage, occafioned by a clap which was 
contracted eleven years before. There had 
been, ever lince that period, a difcharge of 
yellowifh matter that might be faid to ebb 
and flow, being very copious at one time, and 
quite the reverfe at others; excefs of any 
kind, never failed to encreafe it very confix 


[ 102 ] 

derably. Within the laft three years he per¬ 
ceived the urethra to be materially obftrudted, 
and from that time a new fymptom made its 
appearance, namely, a mixture of femen with 
the old running; in proportion to the en~ 
create of the caruncles, the feminal difcharge 
became more plentiful, infomuch, that dur¬ 
ing the laft four or five months, he very 
feldom made urine or went to ftool, without 
a confiderable quantity of feed being evacu¬ 
ated at the fame time. He informed me of his 
having taken large quantities of the moft bra¬ 
cing and ftrengthening medicines, but with 
no other effe£V,than a temporary palliation of 
the fymptoms. 1 The long continuation of the 
difeafe, added, to a clofe attention to bufinefs, 
made terrible havock with his confiitution, 
reduced him almoft to a jkeleton, and relaxed 
his nerves to fuch a degree, as to render life 
burthenfome in the extreme. The excref- 
cences had fo choaked up the urethra, that 
the fmalleft bougie could not be paffed with¬ 
out great difficulty. I began his cure, by 
attempting to remove thefe obflrudtions, 
being fully convinced that no medicine could 
be of u£b till that was effected. I advifed 


[ ! °3 ] 

•him to wear a bougie both night and day, 
and for as many hours together as the parts 
would admit of, without occafloning pain or 
lofs of reft. His bowels were at the fame 
time kept in proper order by the ufe of gentle 
aperients: to which circumftance it will al¬ 
ways be found indifpenfably neceflary to at¬ 
tend in every complaint of this nature, both 
in order to prevent inflammation, and to ob¬ 
viate any material exertion in the evacuation 
of the feces. His diet was of the moll nu¬ 
tritious kind, but as he at firft had little or 
no appetite, I gave him ftrong deceptions of 
the woods, which loon procured one, and at 
the fame time corrected any latent acrimo¬ 
nious humours : after which, corroborants 
and reftoratives were adminiftered with the 
greateft fuccefs. By thefe means, at the ex¬ 
piration of four months, he was lb far reco¬ 
vered as to imagine himfelf cured ; the medi¬ 
cines however were continued (even or eight 
weeks longer, by which time his health was 
perfectly re-eftablifhed. 


[ 1 °4 ] 


Almost fimilar to the preceding cafe, wa3 
that of a gentleman in the county of Cam¬ 
bridge, who had been afflicted for feveral 
years with a feminal gleet, and had taken a 
great quantity of medicines of different kinds, 
without receiving any material benefit—a cir- 
cumftance not to be wondered at, when we 
confider that the caufe of the difeafe had not 
hitherto been underftood, no attention having 
been paid to a caruncle in the urethra, which 
at laft encreafed fo much, as almoft entirely 
to prevent the paffing of his urine; upon 
this account it was that he made application 
to me, having long before given up all ex¬ 
pectation of removing the feminal gleet, every 
effort for that purpofe having fo repeatedly 
proved abortive. Luckily however, the flop- 
page of urine obliged him to have recourfe 
to the only method that could poflibly remedy 
his old diforder. By ufing bougies, the ure¬ 
thra was cleared of obftruftion in the courfe 
of a few weeks, in confequence of which, 
the feminal difcharge gradually abated, and 


[ ] 

. /. •> A 

with the affiftance of fome internal bracers, 
a radical cure was effected in lefs than five 


A gentleman in the weftern part of Eng¬ 
land, became my patient three years fince, in 
confequence of a feminal weaknefs or gleet, 
which had been his companion for thirteen 
years, and was at length very near putting a 
period to his exiftence, notwithftanding a 
long continued ufe of the moil powerful re- 
ftoratives both in medicine and diet, which, 
had been prefcribed for him by feveral very 
eminent practitioners. 

H e had taken aftringents, balfamics, 
ftrengtheners and bracers of almoft every 
kind, large quantities of bark, fteel, ginfang, 
&c. &c. nor was the cold bath omitted, which 

i A 

in the beginning, he faid, afforded a tempo¬ 
rary relief, but after a few months ufe en¬ 
tirely loft its effeCt. The difeafe had ren¬ 
dered him fo weak, as to be fcarce able to 
walk or ftand upright, and his fpirits were 

P likewife 

[ i° 6 .] 

like wife proper tionably depreffed. He in¬ 
formed me, that his prefent complaints took 
their rife from a clap contracted upwards of 
thirteen years fince, that it was not attended 
with much pain or inflammation, nor were 
any of the fymptoms fuch, as indicated any 
high degree of virulence ; his furgeon, how¬ 
ever, had fupplied him very liberally with 
mercurials and draftic purges, and had con¬ 
tinued them fome weeks, by which means 
his appetite, ftrength, &c. were much im¬ 
paired, and a gleet enfued, which from a 
venereal, degenerated into a feminal one. Fre¬ 
quent noCturnal emiflions of femen inter¬ 
rupted his fieep, and a difeharge of the fame 
kind generally happened whenever he made 
urine pr went to fcool. After having given 
this account, he requefled to have my opinion 
upon his cafe. My anfwer was; that from 
the long continuance of the venereal gleet, I 
fufpected fome excrefcence had formed in the 
urethra, and fhould that be the cafe, I doubted 
not of rendering him very eflential fervice. 
He replied, “ That he did not imagine there 
could be any material obftru&ion in the paf- 
fage, as his urine flowed almofl: as well as 

ever 5 

[ io 7 1 

ever; but that it did not pafs quite fo freely, 
which he attributed wholly to the debility 
of the parts. However, upon examination 
with a bougie, I found a caruncle about four 
inches up the urethra, which, in that place, 
diminifhed its diameter nearly one-third part; 
the reft of the canal was perfectly free from 
either ftrifture or any other obftrudtion: this 
difcovery gave my patient much pleafure, and 
at the fame time great furprife, that fuch a 
fubftance fhould have formed without his 
perceiving it; that was a circumftance, I told 
him, which frequently occurred, and might 
be very eafily accounted for, by only reflecting 
upon the very flow, gradual progrefs of thefe 
carnofities; in the prefent inftance above 
twelve years had elapfed during the forma¬ 
tion of a very fmall one. I then advifed him 
to enter upon the ufe of bougies; and that 
they fhould remain in the urethra as many 
hours as poffible, both night and day, pro¬ 
vided neither pain nor inflammation enfued, 
to prevent which, as well as too great efforts 
in difcharging the feces; his body was kept 
rather in a laxative ftate than otherwife, by 
taking occafionally flos fulphuris, magnefia 

P 2 ajba, 

[ IDS ] 

alba, or ele&arium lenitivum. In the courfb 
of a week he was able to wear the bougies 

i ° 

twelve hours in the twenty-four ; by which 
means a copious difcharge of matter was pro¬ 
duced, and in proportion to that, did the ca¬ 
runcle decreafe, and the feminal evacuation 
abate. In lefs than a month the carnofity 
was removed, and with it the ftimulus which 
had operated fo powerfully upon the fperma- 
tic veflels, &c. At this time I thought cor¬ 
roborative medicines would take the defired 
effect, I accordingly adminiftered them in as 
large dofes, and as repeatedly as his ftomach 
would bear, his diet was likewife of the moft 
nutritious kind, and as fimple as poffible, all 
high feafoned fauces, &c. being ftudioufly 
avoided, together with fpirituous liquors, and 
vegetable acids. By the above method this 
gentleman was reftored to perfect health in 
the fpace of eight months ; he married foot} 
after, and has got an heir to his eftate. 

In thefe cafes I always recommend animal 
food, or a meat diet in preference to any other; 
and when the ftomach is too weak to admit 
of it in fubftance, ftrong foups or broths 
3 muft 

[ I0 9 1 

niuft be extracted from it, and taken very li¬ 
berally. After meals, a glafs or two of good 
old Madeira or Mountain wine may be drank, 
and will generally prove beneficial. Mode¬ 
rate exercife will likewife be ufeful, but 
great care mu ft be had that it never amounts 
to fatigue. The patient fhould be thinly 
clad both night and day; rife early, and go 
to bed the fame. I fine, the fame regimen 
may be obferved in thefe complaints as is ge¬ 
nerally recommended in thofe termed nervous. 

All excrefcences or carnofities in the ure¬ 
thra have not a venereal origin, that, in com¬ 
mon with every other glandulous membrane, 
may certainly produce them from fome other 
caufes ; among which, coarfe gravel and fmall 
rough or (harp flones pafling through this 
tube may fometimes occafion them. An in- 
fiance of this kind I remember to have feen 

RuTk * • 

in a Kentifh farmer, who applied to me on 
account of obftrudiions in the urethra, which 
pould not be fuppofed to arife from any ve¬ 
nereal caufe, as he folemnly declared, that he 
had never been fo infe£ted. He had however 

» _ ■ * i . .1 

frequently voided gravel and ftones with his 


[ no ] 

urine ; which, I make not the leaft doubt, 
gave rife to the excrefcences, from having 
wounded the membrane, which afterwards 
healed, but not without producing thefefungi. 

The glandulous membrane that lines the 
nofe, we know will fometimes fend forth ex¬ 
crefcences named polypi, independent of any 
venereal matter whatever. 

Before we clofe our obfervations upon 
gleets and weakneftes, let us turn our thoughts 

O O 

upon thofe which are peculiar to the fair fex. 

The leucorrhssa, fluor albus, or the difeafe 
vulgarly termed the whites, though often 
with very great impropriety, the difcharge 
being at times as high coloured as that pro¬ 
duced by the venereal virus itfelf. This 
gleet is the caufe of many diforders, and as 
frequently the confequence of others. It 
fometimes arifes merely from a cacochymia, 
at others from a profluvium mcnjium , bad la¬ 
bours, mifcarriages, a general relaxation, im¬ 
moderate venery, acrimonious humours, &c. 
When this difcharge is very copious and of 

[ III ] 

long duration, it produces many very difa- 
greeable (if not fatal) effects: it may give 
rife to the whole tribe of what are called 
nervous complaints, hyfterics, &c. and may 
fometimes occafion an atrophy or confump- 
tion. It is to be lamented, that they are 
moft fubjedt to this diforder, who apparently 
are the lead: able to fuftain it, namely, thofe 
of the moft delicate frames and conftitutions. 
A fedentary mode of living, improper diet, too 
much cloathing, bed-warming and tea drink* 
ing, contribute greatly to encreafe, if not to 
produce this difeafe : the ufe of ftrong liquors 
(lam afraid) may fometimes be added to the 
catalogue of caufes. From a defire of becoming 
more delicate, many good conftitutions have 
been greatly injured, (if not entirely ruined) 
by the too frequent repetition of phlebotomy 
and ftrong cathartics. The pudenda of each 

fex being generally very much benefitted by 


cold bathing, why, in the name of common 
fenfe, is it not more frequently pradlifed ? 
Women, in particular, would derive infinite 
advantage from wafhing thefe parts regularly 
night and morning with cold water, except 
at the time of menftruation ; as I believe that 


t 1X2 ] 

few things would tend more to prevent the 
difeafe in queftion than thefe ablutions, if 
properly purfued. An immerfion of the whole 
body would certainly be preferable to a partial 
bath, but as the former is not always practi¬ 
cable, and is generally attended with great 
trouble and inconvenience, we muft content 
ourfelves with the latter, provided it be dili¬ 
gently perfifted in. Certain feds are ftriCtly 
enjoined to make frequent ablutions, as a ce¬ 
remony or duty incumbent on the profeffors 
of fuch religions: a cuftom, howxver, of this 
kind, (if viewed only in a temporal light) 
mu ft be highly beneficial to fociety. Can 
any good reafon be affigned, why the external- 
parts of generation fhould not be as often 
walhed as our faces, they mu ft certainly re¬ 
quire it as frequently, although feldom expofed 
to view? Courtefans (for more reafons than 
one) are the ftrifteft obfervers of this falutary 
cuftom. The great difficulty attending the 
cure of the fluor albus, may in fome degree 
be afcribed to the very lax texture and de¬ 
pending fituation of the parts fubjeCt to this 

C 1 *3 3 

In the cure of female gleets, we muft ad- 
minifter fuch alteratives as will remove any 
latent acrimony, and at the fame time recom¬ 
mend the moft nutritious diet, together with 
a proper regulation of the other non-naturals. 
After the blood and juices fhall have been 
fufficiently purified by the means abovemen- 
tioned ; then may balfamics and aftrigents be 
ufed to great advantage. Be it remembered 
alfo, that we muft not rely folely upon inter- 
nals, for it will generally be found neceftary 
to ufe topical applications at the farne time, 
viz. lotions and injections, which muft be 
compofed of the moft powerful aftringents. 
The cold bath will like wife be of fervice, 
where unfound vifcera or very great teqder- 
nefs of lungs do not prohibit the ufe of it. 
The alteratives recommended in the former 
part of this Eflay, will, upon trial, be allowed ' 
the moft efficacious ones in the prefent com¬ 
plaint. Opiates, in many ftages of the dif- 
eafe, may likewife be adminiftered to very 
great advantage, provided they be fo cor¬ 
rected, as to obviate any material conftipation 
of body. Of all the non-naturals, a due 
regulation of the paffions muft be very ftrictly 

Q attended 

[ ”4 ] 

attended to; nay, it will be found indifpen- 
fably neceffary, as without it no cure will ever 
be obtained; indeed, it will generally prove 
one grand effential in the cure of many female 
complaints. That the vagina uteri, and its 
vicinities are very liable to great defluxions, 
is fufficiently evident from the difeafe juft 
now mentioned, which in general does not 
make its appearance before the age of puberty: 
fome females however, even in the infant 
ftate, experience fo great a flow of humours, 
as to produce a difcharge, in colour, not un¬ 
like the gonorrhoeal one; and frequently acri¬ 
monious enough, to occafion much inflam¬ 
mation, pain, and tumefaction in thefe parts. 
Several inftances of this kind have fallen un¬ 
der my infpeCtion, and upon enquiry, I have 
generally found that the complaint arofe from 
either a fcorbutic or a ferophuious humour. 
Emollient fomentations and cataplafms, af- 
fifted with gentle purgatives, and mild alte¬ 
rants, will foon abate the fymptoms, which 
generally difappear in the courfe of a few 
days; efpecially if the difcharge has been ra¬ 
ther copious in the beginning. 


[ ”5 ] 

To prevent a relapfe, it will be neceflary 
to keep the inteftines in a laxative ftate, which 
may be eafily effected by the ufe of lac ful- 
phuris, or magnefia alba; the preference 
however muft be given to the former, as it 
will at the fame time prove no insignificant 
alterative. The moft obftinate cafes are fuch 
as derive their origin from a leprous humour, 
one of thefe I remember to have feen ; it was 
attended with a very high degree of inflam¬ 
mation, and required vensefeCtion, opiates and 
cathartics, together with the moft powerful 
internal alteratives, and external emollients. 
A composition of camphor, antimony and 
fulphur, was in this cafe extremely ufeful; 
the cure indeed might with juftice be wholly 
afcribed to it; every other medicine having 
proved ineffectual. 

The cure of gleets and weakneffes in either 
fex, will generally require a considerable time, 
but if the methods I have recommended be 
put in practice, and properly purfued, I am 
firmly perfuaded that they will very feidom 
fail of fuccefs. 

F I N I 3