Author index
Abe, M. 30
Acton, R.T. 166
Ahrén, B. 333
Akanuma, Y. 44
Albarran, R.de 89
Alberti, K.G.M.M. 392, 420
Albrecht, G. 315
Amorosa, L.F. 355
An, T. 449
Andersen, A.R. 361
Aro, A. 453
Artal, R. 65
Asmal, A.C. 20
Asp, N.-G. 272
Asplin, C.M. 203
Assal, J.-Ph. 255
Baba, S. 379
Bach, F.H. 415
Baird, H.R. 127
Baldissera, F.G.A. 223
Balkau, B. 39
Barbosa, J. 170, 415
Barger, B.O. 166
Barr, D. 266
Barradas, M.A. 89
Barry, P.J. 173
Baynes, J.W. 93
Becker, K. 282
Bennett, 127
Bennion, L.J. 127
Berger, M. 441
Betterle,C. 431
Billaudel, B. 76
Birtwell, A.J. 261
Boberg, M. 272
Bompiani,G.D. 426
Bonde-Petersen, F. 328
Bottazzo,G.F. 241
Boulton, A.J.M. 15
Bretzel, R.G. 169
British Multicentre Study
Group 109
Bruining, G.J. 24
Bruining, H.A. 24
Budowle, B. 166
Burge, C.T.R. 261
Burnstock, G. 81
Businger, J. 278
Byrne, E. 250
Cagliero, E. 218
Campbell, I.W. 437
Capito, K. 375
Cerasi, E. 142, 146
Chavers, B. 415
Chisholm, D.J. 208
Christensen, N.J. 328
Clarke, B.F. 437
Cobelli, C. 314
Colle, E. 310
Collier,G. 50
Cook, D. 420
Corrall, R.J.M. 445
Corrigan, C.B. 333
Creutzfeldt, W. 441
Crockett, M. 81
Cudworth, A.G. 15
Damoiseaux, P. 255
Dandona, P. 89
Davidson, M.B. 473
Davies, C.J. 261
Deckert, T. 361
Deleers, M. 55
Dornan, T.L. 199
Douglas, C.A. 266
Drury, J. 15
Duner, E. 314
Dyrberg, T. 159
Ebert, R. 441
Eichler, H.G. 278
Eisele, S.G. 60
Ejiri, K. 379
Elliott, R.B. 297
Engle, M.J. 60
Enzmann, F. 169
Eriksson, C.J.P. 34
Etzwiler, D. 415
Falt, K. 282
Falkmer, S. 282
Farrell, P.M. 60
Faure, A. 76
Federlin, K. 169
Feingold, K.R. 234
Fischer, U. 315
Flock, E.V. 127
Foster, D.M. 349
Foulis, A.K. 456
Francis, A.J. 420
Franetzki, M. 169
French, R.R. 466
Frenckell, R. von 229
Frokjzr Thomsen, O. 361
Fujii, S. 379
Gagliardino, J.J. 290
Galluzzo, A. 426
Gambhir, K.K. 89
Gasic, S. 278
Gechter, F. 150
Gelsthorpe, K. 266
Genovese, S. 116
Gepts, W. 282
Giordano, C. 426
Girard, J. 103
Go, R.C.P. 166
Goldstein, D.E. 214
Gomez Dumm,C.L. 290
Gragnoli,G. 411
Green, A. 190, 195
Greniman, M. 328
Greten, H. 366
Groop, L. 34
Gustafsson, I.-B. 272
Hadden, D.R. 250
Haring, H.U. 462
Haffner, S.M. 349
Hage, C. 142
Hagura,R. 44
Hahn, C. 255
Hammond, M.G. 20
Hanning, I. 266, 420
Hansen, B. 169
Hansen, J.A. 199
Harano, Y. 343
Hardisty,C.A. 15
Hari, J. 379
Harley, J.M.G. 250
Hashimoto, N. 449
Hasslacher, Ch. 150
Haven, A.J. 81
Hazzard, W.R. 349
Hedeskov, C.J. 375
Heding, L.G. 261
Heine, R.J. 420
Hellerstrém, C. 393
Hellqvist, L.N.B. 370
Henriksen, T. 218
Hernandez, R.E. 290
Heyburn, P. 261
Hidaka, H. 343
Hillson, R.M. 6, 122
Hilsted, J. 328
Hockaday, T.D.R. 6, 122
Hollander, P.M. 203
Holst, J.J. 223
Hougaard, P. 190
Howell, S.L. 319
Hutson, J.C. 155
Hutton, R.A. 89
Huupponen, R. 34
Hyosu, T. 343
Ikeda, Y. 30
Imamura, Y. 379
Ishihara, K. 379
Ito, H. 134
Jarrett, R.J. 99, 401
Joffe, S. 65
Johansen, K. 180, 406
Johnston, C. 1
Jones, 1.R. 261
Jovanovic, L. 214
Jutzi, E. 315
Kadowaki, T. 44
Kahn, C.R. 229
Kajinuma, H. 44
Kanatsuka, A. 449
Karlstrém, B. 272
Kashiwagi, A. 343
Kataoka, K. 30
Kazumi, T. 379
Keen, H. 401
Keller, U. 103
Kemmler, W. 462
Kemnitz, J.W. 60
Kennedy, L. 93
475
Kerner, W. 169
Khachadurian, A.K. 355
King, H. 39
Kirsch, D. 462
Kohner, E.M. 173
Korhonen, T. 453
Korn, A. 278
Kosaka, K. 44
Kosugi, K. 343
Kraegen, E.W. 208
Krone, W. 366
Kiihn-Velten, N. 300
Kuntschen, F. 255
Kushwaha, R.S. 349
Kuzuya, N. 44
Lager, 1. 337
Larkins, R.G. 304
Lear, S.R. 234
Lernmark, A. 159
Levy, J. 142
Lewin, 1.G. 445
Lincoln, J. 81
Lindeman, J. 24
Lindsay, K.A. 60
Lithell, H. 272
Lorup, B. 180
Lorenzi, M. 218
Ludvigsson, J. 138
Luzio, S. 261
Mackintosh, D. 401
Makino, H. 449
Malaisse, W.J. 55
Mancini, M. 116
Mari, A. 314
Markey, B. 218
Marliss, E.B. 159
Marner, B. 24
Martin, J.M. 297
Maruyama, T. 30
Massi Benedetti, M. 169
Mastranzo, P. 116
Mathiesen, E.R. 406
Matsuba, I. 30
Matsuki, S.. 30
McAuley, R.R. 250
McClure, G. 250
McCulloch, D.K. 437
McLean, A. 50
Michael, A.F. 415
Miyake, Y. 44
Molenaar, J. 24
Mollo, F. 314
Monciotti, C.M. 431
Morgan, M.H. 445
Morita, I. 134
Moser, A.H. 234
Miintefering, H. 282
Murota,S. 134
Nagulesparan, M. 127
Nakhooda, F. 159
Navalescu, I. 169
Nerurkar, S.G. 89
|
We :
Prat
4
476
Nesher, R. 142, 146
Newton, D.J. 122
Niederau, C. 441
Norgaard, M.-B. 328
Nosadini, R. 314
@rskov, H. 420
O'Brian, I1.A.D. 445
O’Dea, K. 50
Omar, M.A.K. 20
Osegawa, M. 449
Owens, D.R. 261
Oxenboll, B. 406
Pacioni, D. 116
Palmer, J.P. 199, 203
Parving, H.-H. 328
Pedini, B. 431
Pelkonen, R. 34
Penttila, I. 453
Perelman, R.H. 60
Pernet, A. 255, 420
Peterson, C.M. 214
Pfeiffer, E.F. 169
Pirson, W. 278
Ponchner, M. 420
Poussier, P. 159
Prescott, R.J. 437
Presotto, F. 431
Pyke, D.A. 1
Raghu, P.K. 199
Rahier, J. 282
Raper, L.R. 39
Rapp, L.B. 431
Raptis, S. 169
Raskin, P. 214
Re, C.A. 304
Rebolledo, O.R. 290
Reeves, W.G. 266
Reichenbacher, R. 150
Renold, A.E. 255
Rhodes, C.J. 370
Riccardi,G. 116
Rich, S. 170
Rigon, F. 431
Rinninger, F. 462
Rivellese, A. 116
Roberts, A.P. 389
Roseman, J.M. 166
Rubino, G. 426
Ruderman, N.B. 355
Ryall, R.G. 389
Saito, Y. 134
Salzsieder, E. 315
Sampietro, T. 218
Sandahl Christiansen, J. 361
Sandler, S. 386
Sarlund, H. 453
Savage, P.J. 127
Schenck, H. von 337
Schermer, R. 300
Schneider, S.H. 355
Schnell, H. 103
Seemayer, T.A. 310
Semino, M.C. 290
Shamoon, H. 183
Sherwin, R. 183
Shigeta, Y. 343
Shii, K. 379
Siegel, E. 441
Signorini, A.M. 411
Sims, E.A.H. 88
Skene, A. 266
Smith, U. 337
Sodoyez-Goffaux, F. 229
Sodoyez, J.C. 229
Solander, F. 195
Sperling, M.A. 65
Spiro, M.J. 70
Staib, W. 300
Starke, A. 441
Stauffacher, W. 103
Stewart, J.A. 456
Story, C.J. 389
Stremmel, W. 441
Strohmeyer, G. 441
Sutter, B.Ch.J. 76
Suzuki, M. 328, 343
Suzuki, T. 449
Svendsen, P.Aa. 180, 406
Takahashi, R. 134
Takaku, F. 44
Takei, I. 30
Tanganelli, I. 411
Taniguchi, H. 379
Taniyama, M. 30
Tattersall, R.B. 266
Taylor, K.W. 370
Taylor, R. 392
Thams, P. 375
Timpl, R. 150
Treves, S. 229
Trimble, E.R. 255
Trotter, I. 250
Tsuruoka, A. 30
Tuch, B. 142
Tuk, C.W. 24
Tuunainen, A. 453
Uno, S. 343
Uusitupa, M. 453
Vasquez, B. 127
Veroni, M.C. 304
Vessby, B. 272
Viberti,G. 401
Waldhausl, W. 12, 169
Waldman, L. 146
Ward, J.D. 15
Weinberg, C.R. 199
Wells, L. 266
Werner, I. 272
Werther, G.A. 65
Wiles, P.G. 1
Wilson, R.M. 266
Wiseman, M. 401
Witztum, J.L. 218
Wolf, E. 15
Worth, R.C. 15
Yaso, S. 379
Ylikahri, R. 34
Yokono, K. 379
York, D.A. 466
Young, R.J. 437
Zanette, F. 431
Zimmet, P. 39
HEE
Subject index
Key: c=correspondence, r= review
A cell, pancreatic — glucose regulation 203
Adenine nucleotide metabolism in diabetes
89c
Adenylate cyclase - enhancing factor from
mouse pancreas 375
— regulation in adipocyte membrane — ob/ob
mice 466
Adrenergic innervation — diabetic rat 81
AIDSPIT - workshop report 169
Albumin deposition — in dermal capillary
basement membrane 415
Aldose reductase inhibitor — in symptomatic
diabetic neuropathy 445
a-amylase inhibitor — effect on post-prandial
glucose 278
Androgen binding protein — streptozotocin
diabetes — rat 300
Apolipoprotein B — catabolism in Type 1
diabetes 349
Arachidonic acid — platelet phospholipid —
Type 2 diabetes 134
Artificial insulin delivery systems — workshop
169
Artificial pancreas — see glucose clamp
p-adrenergic blockade — Type 1 diabetes 183
B-cell damage in diabetic insulitis 241 r
— function — insulin antibodies in diabetic
children 138
— function - review 393r
Basement membrane collagen - UDP-ga-
lactose — diabetic rat 70
— glomerular — type IV collagen — rats 150
British multicentre study group — proliferative
retinopathy — Xenon arc 109
Calcium — distribution in B cells 290
Chiorpropamide - it’s role in determining
CPAF 34
Chlorpropamide alcohol flush —- see CPAF
Cholesterol synthesis — Chinese hamsters —
ob/ob mice — db/db mice 234
Cholinergic innervation — diabetic rat 81
Coronary artery disease — Type 2 diabetes 99r
CPAF - a critical reappraisal 6r
— role of chlorpropamide, alcohol and
acetaldehyde 34
— to flush or not to flush? 12r
— the case in favour 1r
CSII - kinetic modelling studies 208
Diet — cereal fibre in Type 2 diabetes 272
Dietary fibre — and carbohydrate — metabolic
control in diabetes 116
— protein — a trigger of insulin-dependent
diabetes in BB rat 297
Dimethyl urea — protection against
hyperglycaemia 386
Epidemiology — diabetes in Tanzania 333
— impaired glucose tolerance in Naura 39
— mortality in insulin-treated diabetes —
Denmark 190
— use of hospital services by insulin-treated
diabetics 195
Erythrocyte 2,3-bisphosphoglycerate in
Type 1 diabetes 389
Exercise - control in Type 2 diabetes 355
Exocrine pancreas -— autopsy findings in
Type 1 diabetes 456
Experimental diabetes — glomerular
vasement membrane - type IV collagen 150
Factors governing the human immune
response to injected insulin 266
Fibre, cereal — Type 2 diabetes 272
Gastrin response — in patients with vagal
neuropathy 445
GIP - effect of fat and carbohydrate ingestion
on response 50
Gliquidone — extrapancreatic actions — rat
462
Glucagon deficiency associated with
hypoglycaemia 473 c
— infusion — in Type 1 diabetes 337
— related peptides in the human
gastrointestinal mucosa 223
Glucose clamp — and manual technique for
assessing insulin sensitivity 420
Glucose tolerance — natural history in Naura
39
- risk factors for worsening to diabetes 44
Glucose utilization — opiates — dog 65
Glycosuria — renal threshold in Type 1
diabetes 180
Glycosylation, non-enzymic — chronic
diabetic complications 93 r
Growth hormone - ketone body kinetics 103
Guar gum - metabolic response in Type 2
diabetes 453
Haemoglobin, glycosylated — evaluation of
assays 214
HLA-A, B, C and D in South African blacks
— Type 1 diabetes 20
— seasonal patterns of diagnosis of Type 1
diabetes 199
How does glucose regulate the human
pancreatic A cell in vivo? 203
Human endothelial cells — interaction with
LDL and glucose 218
Hyperinsuli ia — non-cirrhotic
haemochromatosis 441
Hyperproinsulinaemia in cirrhosis 392
Hypoglycaemia — f-adrenergic blockade in
Type 1 diabetes 183
— insulin induced — haemodynamic changes
in normal man 328
— persistent neonatal — B and D cells 282
Immune response to injected insulin 266
Impotence — natural history in diabetic men
437
Insulin action — opiates modulate in dogs 65
— antibodies -— B cell function in diabetic
children 138
— degradation - impaired in non-cirrhotic
haemochromatosis 441
— internalization in human erythrocytes 89c
477
— receptor - in vivo imaging and quantitative
analysis 229
— regulation of sterol synthesis 366
— release - sulphonylurea binding — artificial
phospholipid layer 55
— -— suppression of arginine effect by
hyperglycaemia 142
— resistance — insulin concentration in Type 1
diabetes 255
— secretion — a review 319r
— — adrenal interference after oestradiol
treatment 76
— - calcium distribution in B cells 290
— — islet-activating protein 304
— sensitivity - and co-ingestion of fat and
carbohydrate 50
Insulin, isophane — studies in normal subjects
261
Insulin, subcutaneous — estimated absorption
using mathematical model 315c¢
— reply from the authors 315¢
Insulinitis — autopsy findings in newly
diagnosed Type 1 diabetes 456
Islet activating protein — insulin secretion —
NZO mouse 304
Islet cell antibody — review 241r
— time course and characteristics — childhood
diabetes 24
Islet cell surface antibody — cell mediated
cytotoxicity to human pancreatic B cell 30
— precede spontaneous diabetes in BB rat 159
Islet transplantation — workshop 169
Ketone bodies — in Type 1 diabetes 343
LDL, native and glycosylated — interaction
with human endothelial cells 219
Lipolysis — ketone body kinetics and growth
hormone 103
Lymphocyte antibody — precede spontaneous
diabetes in BB rat 159
Mechanism of insulin secretion 319r
Menstrual cycie — changes in food intake —
diabetic Rhesus monkey 60
Monoclonal antibody to islet cell surface
antigens 379
Natural history of impotence in diabetic men
437
Nephropathy, diabetic — incipient in Type 1
diabetes 406
— long-term Type 1 diabetes 361
Neuropathy, autonomic
— early hormonal changes - rat 81
— impotence in diabetic men 437
— vagus and gastrin response 445
Neuropathy — genetic and metabolic studies
15
— use of aldose reductase inhibitor 445
— vibration sense and hyperglycaemia 122
Non-enzymic glycosylation and the chronic
complications of diabetes 93r
NPH insulin — studies in normal subjects 261
478
Oestradiol treatment — adrenal interference of
insulin secretion 76
Opiates - modulaticn of insulin action - dogs
65
Organ specific auto-immunity — in Type 1
diabetic families 431
Paediatric immunology 316
Pancreatic B cell — life story of 393r
Pancreatic cellular infiltrates - New Zealand
black mice 310
Photocoagulation — prevention of blindness
173r
— Xenon arc in proliferative retinopathy 109
Pregnancy, diabetic - changes in food intake
— Rhesus monkey 60
Prevention of blindness in diabetic
retinopathy 173r
Proteinuria — sustained reduction in Type 2
diabetes 127
Renal threshold — for glucose in Type 1
diabetes 180
Retinopathy, proliferative —
photocoagulation using Xenon arc 109
— prevention of blindness 173r
Sertoli cells — altered response under
similated diabetic condition 155
Sorbibil — use in diabetic neuropathy 445
Subcutaneous insulin infusion — kinetic
modelling studies 208
Sugar nucleotides — effect of diabetes — rat 70
— binding to an artificial phospholipid layer
55
Sulphonylurea — extrapancreatic actions of
Gliquidone 462
T lymphocyte subset — in newly diagnosed
Type 1 diabetes 426
Time-dependent inhibition of insulin release
142, 146
Trestatin — a-amylase inhibitor 278
Type 1 diabetes — apolipoprotein catabolism
349
— arterial pressure and micro-albuminuria 401
— auto-immunity in probands and relatives
431
— autopsy results on newly diagnosed
children 456
— P-adrenergic blockade 183
— cell-mediated cytotoxic islet cell surface
antibody 30
complement component C4 in black
Americans 166
deposition of albumin in dermis 415
erythrocyte 2,3-biphosphoglycerate 389
genetic heterogeneity 170c
glucagon infusion 337
glycosylation of urinary proteins 411
health of children of diabetic mothers 250
HLA heterogeneity and season 199
HLA in South African blacks 20
incipient nephropathy 406
insulin resistance and plasma insulin
concentration 255
insulitis 241r
Subject index
— ketone bodies as markers 343
- monoclonal antibody probe - mouse 379
— nephropathy 361
— newly diagnosed, and T subset lymphocyte
deficiency 426
— renal threshold for glucose 180
Type 2 diabetes —- arachidonic acid and
platelet phospholipid 134
— coronary artery disease — chicken or egg!
99r
- effect of a-amylase inhibitor 278
— exercise and control 355
— hyperglycaemia and vibration sense 122
— metabolic response to breakfast and guar
gum 453
— progression from glucose intolerance 44
- proteinuria reduction and hyperglycaemia
127
— UK therapy study 88¢
Type IV collagen — and glomerular basement
membrane - rats 150
UDP-galactose — diabetes — rat 70
Urinary albumin excretion — Type 1 diabetes
401
Urinary protein glycosylation — Type 1
diabetes 411
Viruses — diabetes and encephalomyocarditis
virus 370
Workshop report — artificial insulin delivery
systems 169
— pancreas and islet transplantation 169
4
a